Results 121 to 130 of about 12,660 (287)

Poly(amino acid) Synthesis from 2,5‐Diketopiperazines for Acid‐Actuated Drug Release

Macromolecular Materials and Engineering, EarlyView.
The ring‐opening polymerization (ROP) of 2,5‐diketopiperazines (2,5‐DKPs) to yield poly(amino acids) is reported. This route to poly(amino acids) has circularity, and permits the straightforward production of nanoparticles for controlled release applications.
Patrick A. Wall, Charlie O. H. Sajid, Karen Mitchinson, Paul D. Thornton   +3 more
wiley   +1 more source

The role of disulfide bond replacements in analogues of the Tarantula toxin ProTx-II and their effects on inhibition of the voltage-gated sodium ion channel Nav1.7 [PDF]

, 2017
Spider venom toxins, such as Protoxin-II (ProTx-II), have recently received much attention as selective Nav1.7 channel blockers, with potential to be developed as leads for the treatment of chronic nocioceptive pain.
Cryar, Adam, Dickman, R., Gonen, T., Hall, A., Kilford, I., McCarthy, S., Reyes, F.E., Sanchez-Martinez, S., Tabor, A.B., Takle, A.K., Thalassinos, Konstantinos, Topf, Maya, Wright, Z.V.F.   +12 more
core   +2 more sources

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

Mass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Molecular Surface of JZTX-V (β-Theraphotoxin-Cj2a) Interacting with Voltage-Gated Sodium Channel Subtype NaV1.4

Toxins, 2014
Voltage-gated sodium channels (VGSCs; NaV1.1–NaV1.9) have been proven to be critical in controlling the function of excitable cells, and human genetic evidence shows that aberrant function of these channels causes channelopathies, including epilepsy ...
Ji Luo, Yiya Zhang, Mengting Gong, Shanshan Lu, Yifeng Ma, Xiongzhi Zeng, Songping Liang   +6 more
doaj   +1 more source

Concanavalin a blocks black widow spider toxin stimulation of transmitter release from synaptosomes [PDF]

, 1978
A. Grasso, Stefano Rufini, I. Senni
openalex   +1 more source

ESTIMATING THE VALUE OF BT CORN: A MULTI-STATE COMPARISON [PDF]

Bt corn offers a powerful tool to control European corn borers and some other pests. Because pest infestations and farming practices differ across the Corn Belt, economic benefits also differ.
Dobbins, Craig L., Edwards, C. Richard, Hyde, Jeffrey, Martin, Marshall A., Preckel, Paul V.   +4 more
core   +1 more source

Friends or Foes? Emerging Impacts of Biological Toxins [PDF]

, 2019
Toxins are substances produced from biological sources (e.g., animal, plants, microorganisms) that have deleterious effects on a living organism. Despite the obvious health concerns of being exposed to toxins, they are having substantial positive impacts
Casewell, N.R., Clark, G.C., Elliott, C.T., Harvey, A.L., Jamieson, A.G., Strong, Peter, Turner, A.D.   +6 more
core   +4 more sources

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

PM&R, EarlyView.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae, James M. Shultz, J. Marshall Shepherd, Zelde Espinel, Lauren T. Shapiro   +4 more
wiley   +1 more source

First generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin. [PDF]

Front Microbiol, 2022
de Moraes LFRN, Silva PSE, Pereira TCPL, Almeida Rodrigues TA, Farias Frihling BE, da Costa RA, Torquato HFV, Lima CS, Paredes-Gamero EJ, Migliolo L.   +9 more
europepmc   +1 more source

Key Mechanisms to Mechanically Improve Polyacrylamide‐Based Hydrogels

Journal of Polymer Science, EarlyView.
ABSTRACT Hydrogels usually have weak mechanical properties (e.g., very low elastic modulus and strength of the polyacrylamide hydrogel). To improve the mechanical properties for broader applications, double‐network hydrogels have been developed, such as the polyacrylamide‐alginate hydrogels with the additional alginate network cross‐linked by metal ...
Jing Liu, Xue Chen, Chengguan Zhang, Habibou Maitournam, Yongjun He   +4 more
wiley   +1 more source