Results 131 to 140 of about 356,161 (284)

The Spider Toxin GsMTx-4 Blocks TRPV4 Cation Channels Expressed in HEK-293 Cells [PDF]

, 2015
Christian S.J. Kesselring, Mirjam Krautwald, Yaxin Zhang, Heinrich Brinkmeier   +3 more
openalex   +1 more source

Discovery of broadly-neutralizing antibodies against brown recluse spider and Gadim scorpion sphingomyelinases using consensus toxins as antigens [PDF]

, 2023
Esperanza Rivera‐de‐Torre, Stefanos Lamparidou, Markus‐Frederik Bohn, Seyed Mahdi Kazemi, Andreas H. Laustsen   +4 more
openalex   +1 more source

Acute Toxicity of the Recombinant and Native Phα1β Toxin: New Analgesic from Phoneutria nigriventer Spider Venom

Toxins, 2018
Phα1β, a purified peptide from the venom of the spider Phoneutria nigriventer, and its recombinant form CTK 01512-2 are voltage-dependent calcium channel (CaV) blockers of types N, R, P/Q, and L with a preference for type N. These peptides show analgesic
E. Dallegrave, Eliane Taschetto, Mirna Bainy Leal, Flavia Tasmim Techera Antunes, M. Gomez, Alessandra Hubner de Souza   +5 more
semanticscholar   +1 more source

Molecular Surface of JZTX-V (β-Theraphotoxin-Cj2a) Interacting with Voltage-Gated Sodium Channel Subtype NaV1.4

Toxins, 2014
Voltage-gated sodium channels (VGSCs; NaV1.1–NaV1.9) have been proven to be critical in controlling the function of excitable cells, and human genetic evidence shows that aberrant function of these channels causes channelopathies, including epilepsy ...
Ji Luo, Yiya Zhang, Mengting Gong, Shanshan Lu, Yifeng Ma, Xiongzhi Zeng, Songping Liang   +6 more
doaj   +1 more source

Synthesis and pharmacology of alkanediguanidinium compounds that block the neuronal nicotinic acetylcholine receptor [PDF]

, 1996
Taking as models the polyamine toxin fraction FTX from the funnel-web spider venom, and the guanidinium moiety of guanethidine, a series of azaalkane-1,omega-diguanidinium salts were obtained.
Cueto, Sénida, Gandía, Luis, García Navío, José Luis, García, Antonio G., López, Manuela G., Villarroya, Mercedes, Álvarez-Builla Gómez, Julio   +6 more
core   +3 more sources

A novel tool for the investigation of glutamate release from rat cerebrocortical synaptosomes: the toxin Tx3-3 from the venom of the spider Phoneutria nigriventer [PDF]

, 1996
Marco A. M. Prado, Cristina Guatimosim, Marcus V. Gomez, Carlos R. Diniz, Marta N. Cordeiro, Marco Aurélio Romano‐Silva   +5 more
openalex   +1 more source

Binary architecture of the Nav1.2-β2 signaling complex

eLife, 2016
To investigate the mechanisms by which β-subunits influence Nav channel function, we solved the crystal structure of the β2 extracellular domain at 1.35Å.
Samir Das, John Gilchrist, Frank Bosmans, Filip Van Petegem   +3 more
doaj   +1 more source

Spider Toxin SNX-482 Gating Modifier Spontaneously Partitions in the Membrane Guided by Electrostatic Interactions. [PDF]

Membranes (Basel), 2022
Mellado G, Espinoza N, Espinoza N, Garate JA, Neely A.   +4 more
europepmc   +1 more source

Verified and potential pathogens of predatory mites (Acari: Phytoseiidae) [PDF]

, 2008
Several species of phytoseiid mites (Acari: Phytoseiidae), including species of the genera Amblyseius, Galendromus, Metaseiulus, Neoseiulus, Phytoseiulus and Typhlodromus, are currently reared for biological control of various crop pests and/or as model ...
A Janssen, A Jeyaprakash, AR Weeks, AR Weeks, AR Weeks, AR Weeks, B Lighthart, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, D Skirvin, D Skirvin, DA Raworth, DC Margolies, DG Boucias, DL Johanowicz, DL Johanowicz, DL Johanowicz, DL Johanowicz, DR Horton, DS Yao, E Zchori-Fein, E Zchori-Fein, EAM Beerling, EAM Beerling, EAM Beerling, ES Arutunyan, G Poinar, G Šut’áková, G Šut’áková, G Šut’áková, G Šut’áková, G Šut’áková, G Šut’áková, GJ Moraes De, H Evans, IP Furtado, JA McMurtry, JAJ Breeuwer, JC Lenteren van, JC Lenteren van, JJ Becnel, LA Corpuz-Raros, LE Olsen, LK Tanigoshi, LK Tanigoshi, LPS Geest van der, M Dicke, M Dicke, M Dicke, M Enigl, M Enigl, M Vrie van de, MA Hoy, ME Courcy Williams De, ME Huigens, MS Hunter, MW Sabelis, MW Sabelis, MY Steiner, MY Steiner, MY Steiner, P Schausberger, PP Sikorowski, R Gols, R Pukall, R Stouthamer, R Stouthamer, R Zemek, RT Hess, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Blümel, S Keller, T Maeda, T Maeda, TG Andreadis, TVM Groot, Y Tanada   +89 more
core   +2 more sources

Toxin Fused with SUMO Tag: A New Expression Vector Strategy to Obtain Recombinant Venom Toxins with Easy Tag Removal inside the Bacteria

Toxins, 2017
Many animal toxins may target the same molecules that need to be controlled in certain pathologies; therefore, some toxins have led to the formulation of drugs that are presently used, and many other drugs are still under development.
Lhiri H. A. L. Shimokawa-Falcão, Maria C. Caporrino, Katia C. Barbaro, Maisa S. Della-Casa, Geraldo S. Magalhães   +4 more
doaj   +1 more source