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An insecticidal toxin from Nephila clavata spider venom
Amino Acids, 2017Spiders are the most successful insect predators given that they use their venom containing insecticidal peptides as biochemical weapons for preying. Due to the high specificity and potency of peptidic toxins, discoveries of insecticidal toxins from spider venom have provided an opportunity to obtain natural compounds for agricultural applications ...
Rose Ombati +12 more
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Purification of AMPA type glutamate receptor by a spider toxin
Molecular Brain Research, 1992A glutamate receptor was purified from Triton X-100-solubilized bovine cerebellum membranes. The purification was carried out in two steps: affinity chromatography using a spider toxin (Joro spider toxin; JSTX) immobilized on a lysine-agarose column, and a Mono Q anion exchange column. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE)
Kuniko Shimazaki +4 more
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ChemInform Abstract: Synthesis of Polyamine Analoga of Spider Toxins.
ChemInform, 1994AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
H. Benz, M. Hesse
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Venomics to decrypt the biomedical potential of spider toxins
2016Toxins from venomous animals are extremely potent and selective towards defined targets involved in numerous physiological processes, such as ion channels and receptors. This work aims to develop innovative approaches to elucidate and characterize molecules issued from venoms, potentially exploitable for pharmacological, cosmetics and medical ...
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An Overview of The Three Dimensional Structure of Short Spider Toxins
Toxin Reviews, 2005Arthropods are one of the most diverse animal groups on the Earth. Spiders belong to this phylum and they are ancient animals with a history going back some three hundred million years. They are abundant, widespread, and natural controllers of insect populations. They use their venom to capture prey or to fight against predators.
G. Ferrat, H. Darbon
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Determining the Structures of the Snake and Spider Toxins by X-Rays
2019Snake and spider venom is a complex mixture that contains proteins, peptides, and small organic and inorganic compounds. In contrast to spider venom, snake venom proteins are well known both functionally and structurally. This work describes methods for purification and crystallization of snake and spider venom toxins and their three-dimensional ...
Anwar Ullah +3 more
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A Note on the Evolution of Spider Toxins Containing the Ick-Motif
Toxin Reviews, 2005Most spider neurotoxins comprise a large group of structurally related polypeptides adopting the inhibitor cystine knot motif (ICK). The plethora of interesting biological functions they perform makes them worthy to study the evolutionary patterns that have been shaping their functional diversification.
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Modulation of insect Cav channels by peptidic spider toxins
Toxicon, 2007Insects have a much smaller repertoire of voltage-gated calcium (Ca(V)) channels than vertebrates. Drosophila melanogaster harbors only a single ortholog of each of the vertebrate Ca(V)1, Ca(V)2, and Ca(V)3 subtypes, although its basal inventory is expanded by alternative splicing and editing of Ca(V) channel transcripts. Nevertheless, there appears to
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Side Effects of Bacillus thuringiensis Toxins on Spiders
2012While insecticidal crystal (Cry) proteins produced by Bacillus thuringiensis (Bt) have been used for pest control for almost a century, genetically engineered (GE) plants producing Cry proteins are commercially grown since 1996. For toxicity, Cry proteins need to be ingested, gut environment needs to be suitable, and specific receptors need to be ...
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Spider Toxins: Recent Applications in Neurobiology
Annual Review of Neuroscience, 1989Hunter Jackson, Thomas N. Parks
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