Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. [PDF]
Br J Pharmacol, 2017 Cardoso FC +8 more
europepmc +3 more sources
A novel spider toxin as a selective antagonist of the Kv1 subfamily of voltage-gated potassium channels through gating modulation. [PDF]
J Biol ChemXiao Z +10 more
europepmc +2 more sources
Identification and Evolutionary Analysis of the Widely Distributed CAP Superfamily in Spider Venom [PDF]
ToxinsVenom plays a crucial role in the defense and predation of venomous animals. Spiders (Araneae) are among the most successful predators and have a fascinating venom composition. Their venom mainly contains disulfide-rich peptides and large proteins. Here,
Hongcen Jiang +5 more
doaj +2 more sources
Efficacy of new and existing chemical biopreparations in controlling apple red spider mite (Panonychus ulmi Koch) [PDF]
E3S Web of Conferences, 2023 This article provides information on the damage caused by the apple red spider mite (Panonychus ulmi Koch) in apple orchards and methods of combating it.
Raxmanov Ahliddin, Sulaymonova Gulasal
doaj +1 more source
Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model. [PDF]
J Venom Anim Toxins Incl Trop Dis, 2018 Silva FRD +8 more
europepmc +3 more sources
The deep-rooted origin of disulfide-rich spider venom toxins
eLife, 2023 Spider venoms are a complex concoction of enzymes, polyamines, inorganic salts, and disulfide-rich peptides (DRPs). Although DRPs are widely distributed and abundant, their bevolutionary origin has remained elusive.
Naeem Yusuf Shaikh, Kartik Sunagar
doaj +1 more source
Toxin diversity revealed by a transcriptomic study of Ornithoctonus huwena. [PDF]
PLoS ONE, 2014 Spider venom comprises a mixture of compounds with diverse biological activities, which are used to capture prey and defend against predators. The peptide components bind a broad range of cellular targets with high affinity and selectivity, and appear to
Yiya Zhang +10 more
doaj +1 more source
ANTIAPOPTOTIC POTENTIAL OF SPIDER TOXINS
Ulyanovsk Medico-biological Journal, 2021 Arthropod peptide toxins rich in disulfide bonds are one of the potential sources of bioactive substances. Due to their structure, toxins have increased stability and are able to bind to ion channels, blocking them or changing the gating mechanism. Some spider toxins bind to different types of calcium channels.
E.V. Yurova +4 more
openaire +1 more source
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]
, 2015 Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa +6 more
core +6 more sources
The lethal toxin from Australian funnel-web spiders is encoded by an intronless gene. [PDF]
PLoS ONE, 2012 Australian funnel-web spiders are generally considered the most dangerous spiders in the world, with envenomations from the Sydney funnel-web spider Atrax robustus resulting in at least 14 human fatalities prior to the introduction of an effective anti ...
Sandy Steffany Pineda +3 more
doaj +1 more source