Successful refolding and NMR structure of rMagi3: A disulfide-rich insecticidal spider toxin. [PDF]
Protein Sci, 2018 Titaux-Delgado G +8 more
europepmc +2 more sources
PnPP‐19, a spider toxin peptide, induces peripheral antinociception through opioid and cannabinoid receptors and inhibition of neutral endopeptidase [PDF]
British Journal of Pharmacology, 2016 Ana Cristina Nogueira Freitas +5 more
openalex +2 more sources
Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV (μ-TRTX-Hh2a) [PDF]
Journal of Biological Chemistry, 2013 Background: The molecular basis for sodium channel inhibition by spider venom peptides is poorly understood. Results: Key toxin residues and structural features important for activity of huwentoxin-IV are identified. Conclusion: Toxin activity involves a
Natali A. Minassian +13 more
openalex +2 more sources
ANTIAPOPTOTIC POTENTIAL OF SPIDER TOXINS [PDF]
Ulyanovsk Medico-biological Journal, 2021 Arthropod peptide toxins rich in disulfide bonds are one of the potential sources of bioactive substances. Due to their structure, toxins have increased stability and are able to bind to ion channels, blocking them or changing the gating mechanism. Some spider toxins bind to different types of calcium channels.
Elena Valer'evna Yurova +4 more
openalex +2 more sources
Modulatory features of the novel spider toxin μ-TRTX-Df1a isolated from the venom of the spider Davus fasciatus. [PDF]
Br J Pharmacol, 2017 Cardoso FC +8 more
europepmc +2 more sources
Efficacy of new and existing chemical biopreparations in controlling apple red spider mite (Panonychus ulmi Koch) [PDF]
E3S Web of Conferences, 2023 This article provides information on the damage caused by the apple red spider mite (Panonychus ulmi Koch) in apple orchards and methods of combating it.
Raxmanov Ahliddin, Sulaymonova Gulasal
doaj +1 more source
The deep-rooted origin of disulfide-rich spider venom toxins
eLife, 2023 Spider venoms are a complex concoction of enzymes, polyamines, inorganic salts, and disulfide-rich peptides (DRPs). Although DRPs are widely distributed and abundant, their bevolutionary origin has remained elusive.
Naeem Yusuf Shaikh, Kartik Sunagar
doaj +1 more source
Toxin diversity revealed by a transcriptomic study of Ornithoctonus huwena. [PDF]
PLoS ONE, 2014 Spider venom comprises a mixture of compounds with diverse biological activities, which are used to capture prey and defend against predators. The peptide components bind a broad range of cellular targets with high affinity and selectivity, and appear to
Yiya Zhang +10 more
doaj +1 more source
The lethal toxin from Australian funnel-web spiders is encoded by an intronless gene. [PDF]
PLoS ONE, 2012 Australian funnel-web spiders are generally considered the most dangerous spiders in the world, with envenomations from the Sydney funnel-web spider Atrax robustus resulting in at least 14 human fatalities prior to the introduction of an effective anti ...
Sandy Steffany Pineda +3 more
doaj +1 more source
Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction [PDF]
, 2015 Botulinum neurotoxins (BoNTs) and some animal neurotoxins (-Bungarotoxin, -Btx, from elapid snakes and -Latrotoxin, -Ltx, from black widow spiders) are pre-synaptic neurotoxins that paralyse motor axon terminals with similar clinical outcomes in patients.
Duregotti, Elisa +6 more
core +6 more sources