Results 41 to 50 of about 12,660 (287)

The envenomation of general physiology throughout the last century. [PDF]

, 2017
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core   +1 more source

ArachnoServer: a database of protein toxins from spiders [PDF]

BMC Genomics, 2009
Venomous animals incapacitate their prey using complex venoms that can contain hundreds of unique protein toxins. The realisation that many of these toxins may have pharmaceutical and insecticidal potential due to their remarkable potency and selectivity against target receptors has led to an explosion in the number of new toxins being discovered and ...
Wood, D L A, Miljenović, T, Cai, S, Raven, R J, Kaas, Q, Escoubas, P, Herzig, Volker, Wilson, D, King, G F   +8 more
openaire   +5 more sources

Effects of transgenic Cry1Ac + CpTI cotton on non-target mealybug pest Ferrisia virgata and its predator Cryptolaemus montrouzieri [PDF]

, 2014
Recently, several invasive mealybugs (Hemiptera: Pseudococcidae) have rapidly spread to Asia and have become a serious threat to the production of cotton including transgenic cotton.
De Clercq, Patrick, Deng, Congshuang, He, Yunyu, Liu, Ping, Pang, Hong, Wu, Hongsheng, Xie, Jiaqin, Zang, Yuhong   +7 more
core   +8 more sources

ATP Released by Injured Neurons Activates Schwann Cells [PDF]

, 2016
Injured nerve terminals of neuromuscular junctions (NMJs) can regenerate. This remarkable and complex response is governed by molecular signals that are exchanged among the cellular components of this synapse: motor axon nerve terminal (MAT ...
Cesare eMontecucco, Cesare eMontecucco, Elisa eDuregotti, Elisanna eBergamin, Kees eJalink, Michela eRigoni, Michele eScorzeto, Samuele eNegro, Umberto eRodella   +8 more
core   +2 more sources

A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

Frontiers in Pharmacology, 2021
Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, even ...
Diana Alvarado, Samuel Cardoso-Arenas, Ligia-Luz Corrales-García, Ligia-Luz Corrales-García, Herlinda Clement, Iván Arenas, Pavel Andrei Montero-Dominguez, Timoteo Olamendi-Portugal, Fernando Zamudio, Agota Csoti, Jesús Borrego, Gyorgy Panyi, Ferenc Papp, Gerardo Corzo   +13 more
doaj   +1 more source

Reply to the Letter “Create Guidelines for Characterization of Venom Peptides” from Dr. Volker Herzig

Toxins, 2016
Regarding our paper “PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina”, published in Toxins 2016, 8, doi:10.3390/toxins8030070 [1].[...]
Marcus Vinicius Gomez
doaj   +1 more source

Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of E.coli [PDF]

, 2014
Background: Animal neurotoxin peptides are valuable probes for investigating ion channel structure/function relationships and represent lead compounds for novel therapeutics and insecticides.
A. Lampert, A.O. O'Reilly, A.R. Cole, B.A. Wallace, Berkmen, Bryksin, Cao, Cestèle, Cestèle, Cohen, Collet, Dutertre, Emsley, Estrada, Froy, Georgiou, Gurevitz, J.L.S. Lopes, Kabsch, Karbat, Klose, Lampert, Lees, Lees, McCoy, Meng, Merdanovic, Mergulhão, Mouhat, Olivera, Oren, Pang, Petersen, Provencher, Schlapschy, Schlapschy, Schwartz, Smart, Whitmore, Winn, Xu, Zhang, Zhang   +42 more
core   +1 more source

Modulation of P2X3 receptors by spider toxins

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012
Recently, the novel peptide named purotoxin-1 (PT1) has been identified in the venom of the spider Geolycosa sp. and shown to exert marked modulatory effects on P2X3 receptors in rat sensory neurons. Here we studied another polypeptide from the same spider venom, purotoxin-2 (PT2), and demonstrated that it also affected activity of mammalian P2X3 ...
Pluzhnikov Ka, Roman A. Romanov, M. F. Bystrova, Yuliya V. Korolkova, Eugene V. Grishin, Stanislav S. Kolesnikov, Olga A. Rogachevskaja, N. V. Kabanova, Alexander A. Vassilevski   +8 more
openaire   +3 more sources

The Molecular Composition of Peptide Toxins in the Venom of Spider Lycosa coelestis as Revealed by cDNA Library and Transcriptomic Sequencing

Toxins, 2023
In the so-called “struggle for existence” competition, the venomous animals developed a smart and effective strategy, envenomation, for predation and defense.
Xiangyue Wu, Yan Chen, Hao Liu, Xiangjin Kong, Xinyao Liang, Yu Zhang, Cheng Tang, Zhonghua Liu   +7 more
doaj   +1 more source

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders [PDF]

, 2014
Background: Spiders have evolved pharmacologically complex venoms that serve to rapidly subdue prey and deter predators. The major toxic factors in most spider venoms are small, disulfide-rich peptides.
Antunes, A, Darling, A, Fry, BG, Kely, L, King, GF, Pineda, SS, Sollod, BL, Sunagar, K, Undheim, EAB, Wilson, D   +9 more
core   +2 more sources