Results 41 to 50 of about 356,161 (284)

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage‐gated sodium channels via a large β‐hairpin loop [PDF]

The FEBS Journal, 2015
Niraj S. Bende, Sławomir Dziemborowicz, Volker Herzig, Venkatraman Ramanujam, Geoffrey W. Brown, Frank Bosmans, Graham M. Nicholson, Glenn F. King, Mehdi Mobli   +8 more
openalex   +2 more sources

LCTX-F2, a Novel Potentiator of Coagulation Factors From the Spider Venom of Lycosa singoriensis

Frontiers in Pharmacology, 2020
Spider venoms contain many functional proteins/peptides such as proteinases, serine/cysteine proteinase inhibitors, insecticidal toxins, and ion channel toxins.
Pengpeng Li, Zhongzhe Zhang, Qiong Liao, Er Meng, James Mwangi, Ren Lai, Mingqiang Rong   +6 more
doaj   +1 more source

Effects of transgenic Cry1Ac + CpTI cotton on non-target mealybug pest Ferrisia virgata and its predator Cryptolaemus montrouzieri [PDF]

, 2014
Recently, several invasive mealybugs (Hemiptera: Pseudococcidae) have rapidly spread to Asia and have become a serious threat to the production of cotton including transgenic cotton.
De Clercq, Patrick, Deng, Congshuang, He, Yunyu, Liu, Ping, Pang, Hong, Wu, Hongsheng, Xie, Jiaqin, Zang, Yuhong   +7 more
core   +8 more sources

De Novo Transcriptome Analysis of the Venom of Latrodectus geometricus with the Discovery of an Insect-Selective Na Channel Modulator

Molecules, 2021
The brown widow spider, Latrodectus geometricus, is a predator of a variety of agricultural insects and is also hazardous for humans. Its venom is a true pharmacopeia representing neurotoxic peptides targeting the ion channels and/or receptors of both ...
Pornsawan Khamtorn, Steve Peigneur, Fernanda Gobbi Amorim, Loïc Quinton, Jan Tytgat, Sakda Daduang   +5 more
doaj   +1 more source

Recombinant Production, NMR Solution Structure, and Membrane Interaction of the Phα1β Toxin, a TRPA1 Modulator from the Brazilian Armed Spider Phoneutria nigriventer

Toxins, 2023
Phα1β (PnTx3–6) is a neurotoxin from the spider Phoneutria nigriventer venom, originally identified as an antagonist of two ion channels involved in nociception: N-type voltage-gated calcium channel (CaV2.2) and TRPA1.
E. Lyukmanova, P. Mironov, D. Kulbatskii, M. Shulepko, A. Paramonov, Elizaveta M. Chernaya, Y. A. Logashina, Y. Andreev, M. Kirpichnikov, Z. Shenkarev   +9 more
semanticscholar   +1 more source

The venom gland transcriptome of Latrodectus tredecimguttatus revealed by deep sequencing and cDNA library analysis. [PDF]

PLoS ONE, 2013
Latrodectus tredecimguttatus, commonly known as black widow spider, is well known for its dangerous bite. Although its venom has been characterized extensively, some fundamental questions about its molecular composition remain unanswered.
Quanze He, Zhigui Duan, Ying Yu, Zhen Liu, Zhonghua Liu, Songping Liang   +5 more
doaj   +1 more source

Native pyroglutamation of huwentoxin-IV: a post-translational modification that increases the trapping ability to the sodium channel. [PDF]

PLoS ONE, 2013
Huwentoxin-IV (HWTX-IV), a tetrodotoxin-sensitive (TTX-s) sodium channel antagonist, is found in the venom of the Chinese spider Ornithoctonus huwena.
Mingqiang Rong, Zhigui Duan, Juliang Chen, Jianglin Li, Yuchen Xiao, Songping Liang   +5 more
doaj   +1 more source

Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics. [PDF]

, 2014
BackgroundAnimal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries.
Ayoub, Nadia A, Clarke, Thomas H, Garb, Jessica E, Haney, Robert A, Hayashi, Cheryl Y   +4 more
core   +2 more sources

VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms

Metabolites, 2020
Spider venoms are highly complex mixtures. Numerous spider venom metabolites are uniquely found in spider venoms and are of interest concerning their potential use in pharmacology, agriculture, and cosmetics.
Yvonne M. Forster, Silvan Reusser, Florian Forster, Stefan Bienz, Laurent Bigler   +4 more
doaj   +1 more source

Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider

Scientific Data, 2023
The Tibellus oblongus spider is an active hunter that does not spin webs and remains highly underinvestigated in terms of the venom composition. Here, we describe venom glands transcriptome and venom proteome analysis for unveiling the polypeptide ...
Yuliya Korolkova, Alexander Mikov, Anna Lobas, Elizaveta Solovyeva, Alexey Surin, Yaroslav Andreev, Mikhail Gorshkov, Sergey Kozlov   +7 more
doaj   +1 more source