Results 51 to 60 of about 356,161 (284)

The envenomation of general physiology throughout the last century. [PDF]

, 2017
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
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Composition and toxicity of venom produced by araneophagous white-tailed spiders (Lamponidae: Lampona sp.)

Scientific Reports, 2022
Prey-specialised spiders are adapted to capture specific prey items, including dangerous prey. The venoms of specialists are often prey-specific and less complex than those of generalists, but their venom composition has not been studied in detail. Here,
Ondřej Michálek, Andrew A. Walker, Ondrej Šedo, Zbyněk Zdráhal, Glenn F. King, Stano Pekár   +5 more
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A Novel Insecticidal Spider Peptide that Affects the Mammalian Voltage-Gated Ion Channel hKv1.5

Frontiers in Pharmacology, 2021
Spider venoms include various peptide toxins that modify the ion currents, mainly of excitable insect cells. Consequently, scientific research on spider venoms has revealed a broad range of peptide toxins with different pharmacological properties, even ...
Diana Alvarado, Samuel Cardoso-Arenas, Ligia-Luz Corrales-García, Ligia-Luz Corrales-García, Herlinda Clement, Iván Arenas, Pavel Andrei Montero-Dominguez, Timoteo Olamendi-Portugal, Fernando Zamudio, Agota Csoti, Jesús Borrego, Gyorgy Panyi, Ferenc Papp, Gerardo Corzo   +13 more
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Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels [PDF]

, 2018
Drugs do not act solely by canonical ligand–receptor binding interactions. Amphiphilic drugs partition into membranes, thereby perturbing bulk lipid bilayer properties and possibly altering the function of membrane proteins.
Aldrich, Richard W., Andersen, Olaf S., Dockendorff, Chris, Dodge, Matthew W., Eum, Kenneth S., Gandhi, Disha M., Ingolfsson, Helgi I., Kapoor, Ruchi, Kimball, Ian H., Martin, Stephen F., Peyear, Thasin, Rusinova, Radda, Sack, Jon T.   +12 more
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The Molecular Composition of Peptide Toxins in the Venom of Spider Lycosa coelestis as Revealed by cDNA Library and Transcriptomic Sequencing

Toxins, 2023
In the so-called “struggle for existence” competition, the venomous animals developed a smart and effective strategy, envenomation, for predation and defense.
Xiangyue Wu, Yan Chen, Hao Liu, Xiangjin Kong, Xinyao Liang, Yu Zhang, Cheng Tang, Zhonghua Liu   +7 more
doaj   +1 more source

ATP Released by Injured Neurons Activates Schwann Cells [PDF]

, 2016
Injured nerve terminals of neuromuscular junctions (NMJs) can regenerate. This remarkable and complex response is governed by molecular signals that are exchanged among the cellular components of this synapse: motor axon nerve terminal (MAT ...
Cesare eMontecucco, Cesare eMontecucco, Elisa eDuregotti, Elisanna eBergamin, Kees eJalink, Michela eRigoni, Michele eScorzeto, Samuele eNegro, Umberto eRodella   +8 more
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Reply to the Letter “Create Guidelines for Characterization of Venom Peptides” from Dr. Volker Herzig

Toxins, 2016
Regarding our paper “PhTx3-4, a Spider Toxin Calcium Channel Blocker, Reduces NMDA-Induced Injury of the Retina”, published in Toxins 2016, 8, doi:10.3390/toxins8030070 [1].[...]
Marcus Vinicius Gomez
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Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis. [PDF]

PLoS ONE, 2016
Envenomation by Loxosceles spider is characterized by the development of dermonecrosis. In previous studies, we have demonstrated that increased expression/secretion of matrix metalloproteinases 2 and 9, induced by Loxosceles intermedia venom Class 2 ...
Mara A Corrêa, Cinthya K Okamoto, Rute M Gonçalves-de-Andrade, Carmen W van den Berg, Denise V Tambourgi   +4 more
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Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix [PDF]

, 2016
© 2016 Elsevier Ltd Sheep flystrike is caused by parasitic flies laying eggs on soiled wool or open wounds, after which the hatched maggots feed on the sheep flesh and often cause large lesions.
Alewood, PF, Bosmans, F, Durek, T, Dziemborowicz, S, Er, SY, Gilchrist, J, Herzig, V, Ikonomopoulou, MP, King, GF, Nicholson, GM, Pineda, SS, Smith, JJ   +11 more
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Chemical Synthesis, Proper Folding, Na_v Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1

Toxins, 2019
Phlotoxin-1 (PhlTx1) is a peptide previously identified in tarantula venom (Phlogius species) that belongs to the inhibitory cysteine-knot (ICK) toxin family.
Sébastien Nicolas, Claude Zoukimian, Frank Bosmans, Jérôme Montnach, Sylvie Diochot, Eva Cuypers, Stephan De Waard, Rémy Béroud, Dietrich Mebs, David Craik, Didier Boturyn, Michel Lazdunski, Jan Tytgat, Michel De Waard   +13 more
doaj   +1 more source