Results 51 to 60 of about 12,660 (287)

Chemical characterization of spider toxin, JSTX and NSTX.

Proceedings of the Japan Academy, Series B, 1986
Yoshio Aramaki, Tadashi Yasuhara, Tsutomu Higashijima, Masanori Yoshioka, Akiko Miwa, Nobufumi Kawai, Terumi Nakajima   +6 more
openalex   +4 more sources

Pharmacology of spider venom toxins

Toxin Reviews, 2014
AbstractSpider venom is an intricate combination of target specific enzymatic and non-enzymatic toxins. In addition, the venom also contains polyamine neurotoxins, ATP, AMP, ADP, guanosine, 2,4,6-trihydroxy purine, γ-aminobutyric acid, glutamic acid, aspartic acid, taurine, histamine, serotonin, tyramine, octomine, nor-adrenaline and inorganic salts ...
Sannaningaiah, D., Subbaiah, G. K., Kempaiah, K.   +2 more
openaire   +3 more sources

Chemical Synthesis, Proper Folding, Na_v Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1

Toxins, 2019
Phlotoxin-1 (PhlTx1) is a peptide previously identified in tarantula venom (Phlogius species) that belongs to the inhibitory cysteine-knot (ICK) toxin family.
Sébastien Nicolas, Claude Zoukimian, Frank Bosmans, Jérôme Montnach, Sylvie Diochot, Eva Cuypers, Stephan De Waard, Rémy Béroud, Dietrich Mebs, David Craik, Didier Boturyn, Michel Lazdunski, Jan Tytgat, Michel De Waard   +13 more
doaj   +1 more source

Recent Advances in Research on Widow Spider Venoms and Toxins [PDF]

Toxins, 2015
Widow spiders have received much attention due to the frequently reported human and animal injures caused by them. Elucidation of the molecular composition and action mechanism of the venoms and toxins has vast implications in the treatment of latrodectism and in the neurobiology and pharmaceutical research.
Shuai Yan, Xianchun Wang
openaire   +4 more sources

Tissue-specific expression of calcium channels [PDF]

, 1993
The high-voltage-activated calcium channel is a multimeric protein complex containing 1, 2/δ, β, and γ subunits. The 1 subunit is the ion conduction channel and contains the binding sites for calcium channel blockers and toxins.
Biel, Biel, Bosse, Bosse, Catterall, Cavalié, Dascal, De Jongh, De Jongh, De Jongh, Diebold, Dubel, Ellis, Fleckenstein, Flockerzi, Glossmann, Guy, Hartzell, Heinemann, Hofmann, Hofmann, Hullin, Hymel, Jay, Jay, Kim, Kim, Klöckner, Lacerda, Mikami, Mintz, Mori, Mundiña-Weilenmann, Nakayama, Norman, Nunoki, Osterrieder, Perez-Reyes, Perez-Reyes, Pragnell, Regulla, Rotman, Ruth, Röhrkasten, Scino, Singer, Snutch, Striessnig, Striessnig, Tanabe, Tanabe, Tanabe, Tsien, Varadi, Wei, Welling, Welling, Williams, Williams, Yatani   +59 more
core   +1 more source

Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels [PDF]

, 2018
Drugs do not act solely by canonical ligand–receptor binding interactions. Amphiphilic drugs partition into membranes, thereby perturbing bulk lipid bilayer properties and possibly altering the function of membrane proteins.
Aldrich, Richard W., Andersen, Olaf S., Dockendorff, Chris, Dodge, Matthew W., Eum, Kenneth S., Gandhi, Disha M., Ingolfsson, Helgi I., Kapoor, Ruchi, Kimball, Ian H., Martin, Stephen F., Peyear, Thasin, Rusinova, Radda, Sack, Jon T.   +12 more
core   +2 more sources

Predictive analysis of B-cell antigenic epitopes in phospholipase D toxins from <i>Loxosceles</i> spiders. [PDF]

Toxicon X
Catalán A, García C, Sambra V, Cadena N, Rojas J, Arán-Sekul T, San Francisco J, Vásquez-Saez V, Muñoz C, Vásquez A, Araya JE.   +10 more
europepmc   +2 more sources

Insect-selective spider toxins targeting voltage-gated sodium channels [PDF]

, 2007
The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate Nav channel gating.
Nicholson, GM
core   +1 more source

Spider neurotoxins targeting voltage-gated sodium channels [PDF]

, 2005
The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides, and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate sodium channel gating and/or kinetics.
Little, MJ, Nicholson, GM
core   +1 more source

Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix [PDF]

, 2016
© 2016 Elsevier Ltd Sheep flystrike is caused by parasitic flies laying eggs on soiled wool or open wounds, after which the hatched maggots feed on the sheep flesh and often cause large lesions.
Alewood, PF, Bosmans, F, Durek, T, Dziemborowicz, S, Er, SY, Gilchrist, J, Herzig, V, Ikonomopoulou, MP, King, GF, Nicholson, GM, Pineda, SS, Smith, JJ   +11 more
core   +1 more source