Results 81 to 90 of about 356,161 (284)
Painful toxins acting at TRPV1 [PDF]
, 2008 Many plant and animal toxins cause aversive behaviors in animals due to their pungent or unpleasant taste or because they cause other unpleasant senstations like pain.
Cromer, B, McIntyre, P
core +1 more source
Modulation of P2X3 receptors by spider toxins
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012 Recently, the novel peptide named purotoxin-1 (PT1) has been identified in the venom of the spider Geolycosa sp. and shown to exert marked modulatory effects on P2X3 receptors in rat sensory neurons. Here we studied another polypeptide from the same spider venom, purotoxin-2 (PT2), and demonstrated that it also affected activity of mammalian P2X3 ...
Kabanova, Natalia V. +8 more
openaire +2 more sources
Advanced Materials Interfaces, EarlyView.Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton +2 more
wiley +1 more source
Frontiers in Chemistry, 2020 Peptide toxins that adopt the inhibitory cystine knot (ICK) scaffold have very stable three-dimensional structures as a result of the conformational constraints imposed by the configuration of the three disulfide bonds that are the hallmark of this fold.
Stephen McCarthy +4 more
doaj +1 more source
Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells. [PDF]
, 2012 Chemokines have a central role in regulating processes essential to the immune function of T cells, such as their migration within lymphoid tissues and targeting of pathogens in sites of inflammation.
Banigan, Edward J +11 more
core +2 more sources
Advanced Materials Technologies, EarlyView.The patch mimics the dual physicochemical adhesion mechanisms of gecko toe micropillars and spider silk proteins, enabling strong interfacial bonding via partially cured micropillars. Its facile fabrication allows customization for precision medicine, while its motion responsiveness offers potential for real‐time wound monitoring.
Chengxin Luan +4 more
wiley +1 more source
Phase coupling of a circadian neuropeptide with rest/activity rhythms detected using a membrane-tethered spider toxin. [PDF]
PLoS Biology, 2008 Drosophila clock neurons are self-sustaining cellular oscillators that rely on negative transcriptional feedback to keep circadian time. Proper regulation of organismal rhythms of physiology and behavior requires coordination of the oscillations of ...
Ying Wu +4 more
doaj +1 more source
The teneurin C-terminal domain possesses nuclease activity and is apoptogenic. [PDF]
, 2018 Teneurins are type 2 transmembrane proteins expressed by developing neurons during periods of synaptogenesis and apoptosis. Neurons expressing teneurin-1 synapse with other teneurin-1-expressing neurons, and neurons expressing teneurin-2 synapse with ...
Chiquet-Ehrismann, Ruth +2 more
core +3 more sources
Advanced Materials Technologies, EarlyView.Soft multimaterial optical fibers integrate multiple functionalities—such as waveguiding, side emission, sensing, drug delivery or actuation—into a single filament for wearable, implantable, and tissue‐integrated devices for diagnostics and phototherapy.
Zahra Kafrashian +2 more
wiley +1 more source
Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration
Advanced Materials Technologies, EarlyView.This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley +1 more source