Results 231 to 240 of about 6,046 (276)

Spider Venomics: Implications for Drug Discovery

Future Medicinal Chemistry, 2014
Over a period of more than 300 million years, spiders have evolved complex venoms containing an extraordinary array of toxins for prey capture and defense against predators. The major components of most spider venoms are small disulfide-bridged peptides that are highly stable and resistant to proteolytic degradation.
Pineda, Sandy S., Undheim, Eivind A. B., Rupasinghe, Darshani B., Ikonomopoulou, Maria P., King, Glenn F.   +4 more
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Collagenolytic activity of snake and spider venoms

Toxicon, 1967
Abstract The venoms of the snakes B. atrox , B. Jararaca , C. durissus , A. piscivorus , and the spiders P. fera , L. erythrognatha possess proteolytic activity which attacks gelatine, casein and azocoll. Denatured (heat, urea) collagen is digested too. However, native collagen is not attacked by the enzymes present in the venoms investigated.
E, Kaiser, W, Raab
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[Venomous spiders and their venoms].

Tierarztliche Praxis, 1985
The history of araneidism is long and confusing. The superstition seems to be inexterminatable that tropical mygalomorphs and mediterranean tarantulas are dangerous for humans. It can be looked up even in the most recent edition of the widespread clinical dictionary of Pschyrembel.
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Venomous snake bites, scorpions, and spiders

2014
Neurologic dysfunction due to natural neurotoxins is an important, but neglected, public health hazard in many parts of the world, particularly in the tropics. These toxins are produced by or found among a variety of live forms that include venomous snakes, arthropods such as scorpions, spiders, centipedes, stinging insects (Hymenoptera), ticks ...
S A M, Kularatne, Nimal, Senanayake
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Proteome and peptidome profiling of spider venoms

Expert Review of Proteomics, 2008
Spider venoms are an important source of novel molecules with different pharmacological properties. Recent technological developments of proteomics, especially mass spectrometry, have greatly promoted the systematic analysis of spider venom. The enormous diversity of venom components between spider species and the lack of complete genome sequence, and ...
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The Venom of Australian Spiders

2015
Australia is home to an estimated 10,000 species of spider, including species from the Latrodectus genera and Atracinae family, two of the four widely recognized medically significant spider groups. It is predicted in excess of 5,000 spider bite cases occurring annually in Australia, predominantly by spiders that have not shown any medical relevance ...
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Toxic and Allergic Reaction to Spider Venom

Journal of Asthma Research, 1976
(1976). Toxic and Allergic Reaction to Spider Venom. Journal of Asthma Research: Vol. 13, No. 4, pp. 185-185.
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Spider Venoms and Their Effect

1987
In principle, with the exception of some groups of spiders which have no venom glands at all (e.g. Uloboridae and Holarchaea) all spiders with any kind of venom apparatus must be considered as venomous, if not always for man, then perhaps for other animals, or at least for insects, their usual prey.
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Polypeptide neurotoxins from spider venoms

European Journal of Biochemistry, 1999
Spider venoms contain a variety of toxic components. The polypeptide toxins are divided into low and high molecular mass types. Small polypeptide toxins interacting with cation channels display spatial structure homology. They can affect the functioning of calcium, sodium, or potassium channels.
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Protocols for Peptidomic Analysis of Spider Venoms

2009
Spider venom contains a complex mixture of components with a large range of molecular masses (0.1-60 kDa) exhibiting a diverse array of actions. Most of these components are proteinaceous molecules - biologically active proteins and peptides. Proteomics profiling of spider venoms (the components with MW >10 kDa) could be achieved through conventional 2-
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