Results 71 to 80 of about 2,873 (206)

Beyond Manoeuvre Theory for European Defence

Global Policy, EarlyView.
ABSTRACT This article contributes to the debate about European defence in the light of the Russo‐Ukraine war and growing doubts about US commitment to Europe. It argues that Europeans need to fundamentally relearn the ability to imagine military strategy from a European viewpoint.
Lukas Mengelkamp, Sam Vincent
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Red-back spider (Latrodectus hasselti) antivenom prevents the toxicity of widow spider venoms

, 2001
Study objectives: Widow spiders of the genus Latrodectus are found worldwide and produce similar clinical envenomation syndromes. In Australia, red-back spider antivenom (RBS-AV) is effective therapy for Latrodectus hasselti envenomation and it has been ...
Andis Graudins, Kevin Broady, Padula, M, Nicholson, GM, Graudins, A, Matthew Padula, Graham M. Nicholson, Broady, K   +7 more
core   +1 more source

‘We Are Only Playing’: Reflections on the Pandemic's Effects on Immigrant Preschoolers' Mentalisation and Play During the Sand Play Workshops

Children &Society, EarlyView.
ABSTRACT Mentalisation and symbolisation are important processes to support children in understanding their lived experience. By expressing what is most salient to them through pretend play, children can normally develop their capacity to mentalise and symbolise, which helps them cope with adversity.
Caroline Beauregard
wiley   +1 more source

Structure–Function and Therapeutic Potential of Spider Venom-Derived Cysteine Knot Peptides Targeting Sodium Channels

Frontiers in Pharmacology, 2019
Spider venom-derived cysteine knot peptides are a mega-diverse class of molecules that exhibit unique pharmacological properties to modulate key membrane protein targets.
Fernanda C. Cardoso, Richard J. Lewis
doaj   +1 more source

Patient and physician satisfaction with video consultations in dermatology: An exploratory cross‐sectional study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Teledermatology has become an essential part of dermatological care, although challenges in its implementation remain. We conducted a real‐life survey on video consultations over a one‐year period to assess satisfaction and identify barriers.
Felix von Krogh, Julia Zarnowski, Regina Treudler, Jan‐Christoph Simon, Anna‐Theresa Seitz   +4 more
wiley   +1 more source

Functional Profiling of the A-Family of Venom Peptides from the Wolf Spider Lycosa shansia

, 2023
The venoms of spiders from the RTA (retro-lateral tibia apophysis) clade contain diverse short linear peptides (SLPs) that offer a rich source of therapeutic candidates. Many of these peptides have insecticidal, antimicrobial and/or cytolytic activities,
Johanna Eichberg, Hardes, Kornelia, Paas, Anne-Kathrin, Lennart Schulte, Dersch, Ludwig, Sabine Hurka, Andreas Vilcinskas, Tim Lüddecke, Anne Paas, Kornelia Hardes, Oberpaul, Markus, Lüddecke, Tim, Eichberg, Johanna, Vilcinskas, Andreas, Markus Oberpaul, Schulte, Lennart, Ludwig Dersch, Sven Klimpel, Klimpel, Sven, Hurka, Sabine   +19 more
core   +1 more source

She Doesn't Whisper: Female‐Prominent Stridulation Shaped by Morphology in a Buthid Scorpion and Insights on Its Function

Ethology, EarlyView.
Sexual dimorphism and stress‐induced stridulatory responses in Jaguajir rochae (Borelli, 1910). Females exhibited greater absolute pectinal size and higher sound pressure levels, whereas males showed higher pectinal allometric ratios relative to body size, lower sound frequencies, and shorter delta times.
Welton Dionisio‐da‐Silva, Natália Maria Câmara Luna, Patrício Adriano da Rocha, Rodrigo Hirata Willemart, Marcio Bernardino daSilva   +4 more
wiley   +1 more source

Cross-reactivity of Sydney funnel-web spider antivenom: neutralization of the in vitro toxicity of other Australian funnel-web (Atrax and Hadronyche) spider venoms

, 2002
Australian funnel-web spiders are recognized as one of the most venomous spiders to humans world-wide. Funnel-web spider antivenom (FWS AV) reverses clinical effects of envenomation from the bite of Atrax robustus and a small number of related Hadronyche
P.F Alewood, Broady, K. W., G.M Nicholson, Nicholson, G.M., Wilson, D., Broady, K.W., Wilson, D. T. R., Alewood, P.F., Alewood, P. F., Graudins, A., D Wilson, K.W Broady, Nicholson, G. M., A Graudins   +13 more
core   +1 more source

The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

Toxins, 2017
Spider venoms constitute incredibly diverse libraries of compounds, many of which are involved in prey capture and defence. Polyamines are often prevalent in the venom and target ionotropic glutamate receptors. Here we show that a novel spider polyamine,
David Wilson, Glen M. Boyle, Lachlan McIntyre, Matthew J. Nolan, Peter G. Parsons, Jennifer J. Smith, Leon Tribolet, Alex Loukas, Michael J. Liddell, Lachlan D. Rash, Norelle L. Daly   +10 more
doaj   +1 more source