Results 111 to 120 of about 97,509 (188)

Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]

, 1985
We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Franke, Christine A., Hruby, Dennis E., Rice, Charles M., Strauss, James H.   +3 more
core  

Transmissible gastroenteritis virus: Identification of M protein-binding peptide ligands with antiviral and diagnostic potential [PDF]

, 2013
The membrane (M) protein is one of the major structural proteins of coronavirus particles. In this study, the M protein of transmissible gastroenteritis virus (TGEV) was used to biopan a 12-mer phage display random peptide library.
Ren, Xiaofeng, Sestak, Karol, Suo, Siqingaowa, Zarlenga, Dante S., Zou, Hao   +4 more
core   +1 more source

Understanding the Molecular Actions of Spike Glycoprotein in SARS-CoV-2 and Issues of a Novel Therapeutic Strategy for the COVID-19 Vaccine

BioMedInformatics
In vaccine development, many use the spike protein (S protein), which has multiple “spike-like” structures protruding from the spherical structure of the coronavirus, as an antigen. However, there are concerns about its effectiveness and toxicity. When S
Yasunari Matsuzaka, Ryu Yashiro
doaj   +1 more source

Cetacean coronavirus spikes highlight S glycoprotein structural plasticity

AbstractCoronaviruses (CoVs) exhibit a remarkable ability for spill-over infections into naive host populations. While much research has focused on the spike (S) glycoproteins of zoonotic alpha- and betacoronaviruses, the S proteins of gamma- and deltacoronaviruses, which predominantly infect avian hosts, remain poorly understood. Here, we present high-
Ruben J.G. Hulswit, Tatiana M. Shamorkina, Joline van der Lee, Floor Rosman, Lisanne S. Wetzels, Frank J.M. van Kuppeveld, Joost Snijder, Berend Jan Bosch, Daniel L. Hurdiss   +8 more
openaire   +1 more source

The Omicron XBB.1 Variant and Its Descendants: Genomic Mutations, Rapid Dissemination and Notable Characteristics

Biology
The SARS-CoV-2 virus, which is a major threat to human health, has undergone many mutations during the replication process due to errors in the replication steps and modifications in the structure of viral proteins. The XBB variant was identified for the
Raffaele Giancotti, Ugo Lomoio, Barbara Puccio, Giuseppe Tradigo, Patrizia Vizza, Carlo Torti, Pierangelo Veltri, Pietro Hiram Guzzi   +7 more
doaj   +1 more source

A Computational Workflow to Predict Biological Target Mutations: The Spike Glycoprotein Case Study. [PDF]

Molecules, 2023
Cozzini P, Agosta F, Dolcetti G, Dal Palù A.   +3 more
europepmc   +1 more source

Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein. [PDF]

Nat Commun, 2023
Calvaresi V, Wrobel AG, Toporowska J, Hammerschmid D, Doores KJ, Bradshaw RT, Parsons RB, Benton DJ, Roustan C, Reading E, Malim MH, Gamblin SJ, Politis A.   +12 more
europepmc   +1 more source

Cytotoxic T Cells Targeting Spike Glycoprotein Are Associated with Hybrid Immunity to SARS-CoV-2. [PDF]

J Immunol, 2023
Phan JM, Layton ED, Yu KKQ, Aguilar MS, Golez I, Franko NM, Logue JK, Rodda LB, Howard CA, Pepper M, Gale M, Chu HY, Seshadri C.   +12 more
europepmc   +1 more source

Insights from the molecular docking analysis of gambogic acid with the Chikungunya spike glycoprotein E2. [PDF]

Bioinformation, 2023
Qamar S, Syeda A, Amjad Beg M, Irfan Qureshi M.   +3 more
europepmc   +1 more source

Insertion in the N-Terminal Domain of the SARS-CoV-2 Spike Glycoprotein Affects Antibody Recognition and Phenotypic Properties. [PDF]

Viruses
Ermolaeva EA, Zyrina AN, Sirazova DI, Lunin AS, Motov AS, Chernavtseva AD, Gancharova OS, Kozlovskaya LI, Shishova AA, Siniugina AA, Ishmukhametov AA.   +10 more
europepmc   +1 more source