Results 181 to 190 of about 7,075,307 (355)

Targeting SARS-CoV-2 Spike Protein of COVID-19 with Naturally Occurring Phytochemicals: An in Silco Study for Drug Development

, 2020
Spike glycoprotein found on the surface of SARS-CoV-2 (SARS-CoV-2S) is a class I fusion protein which helps the virus in its initial attachment with human Angiotensin converting enzyme 2 (ACE2) receptor and its consecutive fusion with the host cells. The
Shashikant Ray (8682525), Abhijeet Kumar (8682533), Jitendra Subhash Rane (8682530), Abhijeet, Kumar, Jitendra Subhash, Rane, Aroni, Chatterjee, Shashikant, Ray, Aroni Chatterjee (8682531)   +7 more
core   +1 more source

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Kien, F., Nicholls, JM, Bruzzone, R, Chan, C. M., Tsao, SW, Kien, F, Siu, Y. L., Escriou, N, Altmeyer, R., Nal, B., Nicholls, J. M., Chan, CM, Siu, YL, Lo, J, Peiris, J. S. M., Tsao, S. W., Teoh, KT, Nal, B, Teoh, K. T., Peiris, JSM, Altmeyer, R, Lo, J., Escriou, N., Bruzzone, R.   +23 more
core   +1 more source

Designable van der Waals Crystal for Artificial Neuronal Cell Mimicking

Advanced Materials, EarlyView.
Designable van der Waals crystal has been demonstrated for device‐scale neuronal cell mimicking. The structural similarity between ion‐channel in biological membranes and layered vdW lattices is realized with nano‐crystallization via Ar + H2S plasma sulfurization.
Jinhyoung Lee, Gunhyoung Kim, Dongho Lee, Seowoo Son, Hyunho Seok, Sihoon Son, Hyunbin Choi, Geonwook Kim, Geumji Back, Hyunkyu Kim, Chaerin Park, Junmin Ahn, Seongyun Je, Chaeyoung Im, Junil Cho, Magdalena Grzeszczyk, Seongho Kim, Eunseo Go, Hyunwoo Shim, Donghwan Choi, Muyoung Kim, Hyoeng‐U. Kim, Won‐Jun Jang, Taesung Kim   +23 more
wiley   +1 more source

The effect of beta-globin intron and WPRE on transient expression of SARS-CoV-2 spike and generation of pseudotyped lentiviruses

Acta Virologica
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an enveloped, single-stranded RNA virus, is causative of coronavirus disease 2019 (COVID-19).
Hyeop Jin, Ye Rae Cho, Yong Tae Jung
doaj   +1 more source

Programmable Etherified‐Starch Networks Enable Tunable Humidity‐Responsive Soft Actuators for Smart Textiles

Advanced Materials Interfaces, EarlyView.
Programmable etherified‐starch networks enable humidity‐responsive soft actuators with tunable and reversible deformation. By tailoring crosslinking density and structural design, rapid response, controllable actuation, and long‐term stability are achieved.
Dan Zhou, Jieqiong Yao, Kai Kang, Lingfeng Zhu, Zhenfang Zhang, Xin Wei, Yitong Li, Yiwen Zhong, Yingying Zhou, Miao Wang, Ruijun Wu, Yijun Yao, Caijuan Xia, Yang Fu   +13 more
wiley   +1 more source

Identification of a Potent Inhibitor Targeting the Spike Protein of Pandemic Human Coronavirus, SARS-CoV-2 by Computational Methods

, 2020
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is an emerging new viral pathogen that causes severe respiratory disease. SARS-CoV-2 is responsible for an outbreak of COVID-19 pandemic worldwide.
SRUTHI, UNNI, Snehal, Aouti, Padmanabhan, Balasundaram   +2 more
core   +1 more source

Discovery of thiadiazole-based small-molecule inhibitors of SARS-CoV-2 spike-ACE2 interaction through integrated computational prediction and experimental validation

Scientific Reports
The SARS-CoV-2 spike protein enables viral entry by binding to the human ACE2 receptor, making it a critical target for antiviral intervention. In this study, five small molecules derived from 1,3,4-thiadiazole scaffolds were identified as potential ...
Zakkia Gul, Syed Ahsan Shahid, Obaid-ur-Rahman Abid, Muhammad Waqas, Shazia Rafique, Ahmed E. Al-Sabri, Asma Sardar, Afrah F. Alkhuriji, Nawal M. Al-Malahi, Muhammad Irfan, Amjad Ali   +10 more
doaj   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Subcellular location and protein interactions of the infectious bronchitis virus gene 3 and 5 accessory proteins [PDF]

The avian coronavirus infectious bronchitis virus (IBV) expresses four nonstructural, non-gene 1 proteins (3a, 3b, 5a and 5b) which have been shown to be dispensable for virus replication in cell culture.
Davies, Marc Tudor
core  

Type VI secretion system : secretion by a contractile nanomachine [PDF]

, 2015
The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative bacteria. Several key components of T6SS are evolutionarily related to components of contractile nanomachines such as phages and R-type pyocins. The T6SS assembly is
Basler, Marek
core   +1 more source