Results 191 to 200 of about 7,075,307 (355)

Sensitive and Spatially‐Resolved Electrochemiluminescence via Micropatterning

Advanced Materials Interfaces, EarlyView.
The use of a simple silica nanoparticle surface coating and patterning process can transform ordinary gold electrodes into multiplexed ECL sensing electrodes. Through spatially confined droplet formation and local ECL emission, it is possible to perform multiple analyses simultaneously from individual locations as well as intensify the ECL signal by as
Yuliang Shao, Tatiana Starikova, Mengzhen Xi, Maria Vittoria Balli, Emanuele Luigi Sciuto, Gabriele Giagu, Vincenzo Paratore, Carmelo Corsaro, Enza Fazio, Sabrina Conoci, Luca Prodi, Giovanni Valenti, Pavel A. Levkin   +12 more
wiley   +1 more source

Identification of new pharmacophore against SARS-CoV-2 spike protein by multi-fold computational and biochemical techniques

Scientific Reports
COVID-19 appeared as a highly contagious disease after its outbreak in December 2019 by the virus, named SARS-CoV-2. The threat, which originated in Wuhan, China, swiftly became an international emergency.
Atta Ullah, Saeed Ullah, Sobia Ahsan Halim, Muhammad Waqas, Basharat Ali, Farid S. Ataya, Nasser M. El-Sabbagh, Gaber El-Saber Batiha, Satya Kumar Avula, Rene Csuk, Ajmal Khan, Ahmed Al-Harrasi   +11 more
doaj   +1 more source

Femtosecond‐Laser Mould Texturing Enables Tunable Biointerfaces in COC Microfluidics

Advanced Materials Interfaces, EarlyView.
Femtosecond‐laser texturing of injection‐mould inserts enables scalable engineering of biointerfaces in cyclic olefin copolymer microfluidics. Replicated micro‐ and nano‐topographies modulate surface roughness and wettability, leading to texture‐dependent protein adsorption and cell adhesion without chemical post‐processing.
Irene Varela‐Leniz, Nora Larreategi, Laura Gemini, Taieb Bakouche, Florent Husson, Leire Gartzia‐Rivero, Eider Bilbao Castellanos, Ane Miren Zaldua, José Luis Vilas‐Vilela, Leire Etxeberria   +9 more
wiley   +1 more source

Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

Nature Medicine, 2022
P. R. Wratil, Marcel Stern, Alina Priller, A. Willmann, G. Almanzar, E. Vogel, M. Feuerherd, Cho-Chin Cheng, Sarah Yazici, C. Christa, S. Jeske, G. Lupoli, Tim Vogt, M. Albanese, E. Mejías-Pérez, Stefan Bauernfried, N. Graf, H. Mijočević, Martin Vu, Kathrin Tinnefeld, J. Wettengel, D. Hoffmann, M. Muenchhoff, Christopher Dächert, H. Mairhofer, S. Krebs, V. Fingerle, A. Graf, P. Steininger, H. Blum, V. Hornung, B. Liebl, K. Überla, M. Prelog, P. Knolle, O. Keppler, U. Protzer   +36 more
semanticscholar   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Transducers Across Scales and Frequencies: A System‐Level Framework for Multiphysics Integration and Co‐Design

Advanced Materials Technologies, EarlyView.
Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu, Mengyao Xiao, Zhouli Sui, Yinpeng Wang, Daoye Zheng, Yuxin Liu, Luwei Wang, Huajun Liu, Chengkuo Lee   +8 more
wiley   +1 more source

3D Printing of Stretchable, Compressible and Conductive Porous Polyurethane for Soft Robotics

Advanced Materials Technologies, EarlyView.
A 3D‐printable porous dopamine‐polyurethane acrylate elastomer results in conductive, stretchable, and compressible structures that can be metallized in situ through catechol‐mediated silver reduction. The resulting material function as both compliant soft robot with a and strain sensors without complex assemblies, enabling fully 3D‐printed soft ...
Ouriel Bliah, Konstantin Sakharov, Pooi See Lee, Shlomo Magdassi   +3 more
wiley   +1 more source

The disappearing COVID-Naïve Population and comparative Roche vs. Abbott Test sensitivity: evidence from antibody seroprevalence in Milwaukee County, Wisconsin

Scientific Reports
We study the prevalence of SARS-CoV-2 antibodies in a diverse population in Milwaukee County, Wisconsin from May 2021 to June 2022. We find that 99.4% (523/526) of the participants had positive results for antibodies to the SARS CoV2 spike protein over ...
Lorenzo Franchi, Vladimir Atanasov, Mark Stake, Garrett Bates, Kristen Osinski, John R Meurer, Bernard Black   +6 more
doaj   +1 more source

Production and cryo-electron microscopy structure of an internally tagged SARS-CoV-2 spike ecto-domain construct

Journal of Structural Biology: X
The SARS-CoV-2 spike protein is synthesized in the endoplasmic reticulum of host cells, from where it undergoes export to the Golgi and the plasma membrane or retrieval from the Golgi to the endoplasmic reticulum.
Suruchi Singh, Yi Liu, Meghan Burke, Vamseedhar Rayaprolu, Stephen E. Stein, S. Saif Hasan   +5 more
doaj   +1 more source

Graphene‐Interfaced Stretchable Sweat Patch for Multiplexed Electrochemical Monitoring of IL‐6, Glucose, and Calcium Ions

Advanced Materials Technologies, EarlyView.
Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
Roomia Memon, Ali Tufani, Süleyman Çelik, Javed H. Niazi, Anjum Qureshi   +4 more
wiley   +1 more source