Results 51 to 60 of about 47,685 (161)

Unexpected one-pot formation of the 1H-6a,8a-epiminotricyclopenta[a,c,e][8]annulene system from cyclopentanone, ammonia and dimethyl fumarate. Synthesis of highly strained polycyclic nitroxide and EPR study

Beilstein Journal of Organic Chemistry, 2019
The unexpected formation of a highly strained polycyclic amine was observed in a one-pot synthesis from cyclopentanone, dimethyl fumarate and ammonium acetate.
Sergey A. Dobrynin, Igor A. Kirilyuk, Yuri V. Gatilov, Andrey A. Kuzhelev, Olesya A. Krumkacheva, Matvey V. Fedin, Michael K. Bowman, Elena G. Bagryanskaya   +7 more
doaj   +1 more source

Retinal guanylyl cyclase activating protein 1 forms a functional dimer. [PDF]

PLoS ONE, 2018
Retinal guanylyl cyclases (RetGCs) in vertebrate photoreceptors are regulated by the guanylyl cyclase activator proteins (GCAP1 and GCAP2). Here, we report EPR double electron-electron resonance (DEER) studies on the most ubiquitous GCAP isoform, GCAP1 ...
Sunghyuk Lim, Graham Roseman, Igor Peshenko, Grace Manchala, Diana Cudia, Alexander M Dizhoor, Glenn Millhauser, James B Ames   +7 more
doaj   +1 more source

Identifying the Elusive Dimerization Product Interfering with Methylsulfonato‐Group Labeling of Cysteines in Proteins

ChemistryOpen
Many biomolecular studies start with labeling a protein with a fluorescent label, spin label, or chemical label. The methanethiosulfonate (mts)‐linking group suffers from a hitherto not‐understood side reaction that leads to label‐dimerization instead of
Leonardo Passerini, René Dekkers, Karthick Babu Sai Sankar Gupta, Mark Overhand, Martina Huber   +4 more
doaj   +1 more source

Incorporation of Spin Labels and Paramagnetic Tags for Magnetic Resonance Studies Using Cycloaddition Reactions as a Tool

Reactions
The cycloaddition reaction is one of the most common reactions in organic chemistry. It has been applied in various fields. Herein, we focus on the application of cycloaddition reactions in investigating biological molecules and materials using magnetic ...
Amarendra Nath Maity, Amiya Kumar Medda, Shyue-Chu Ke   +2 more
doaj   +1 more source

Simulation vs. reality: a comparison of in silico distance predictions with DEER and FRET measurements. [PDF]

PLoS ONE, 2012
Site specific incorporation of molecular probes such as fluorescent- and nitroxide spin-labels into biomolecules, and subsequent analysis by Förster resonance energy transfer (FRET) and double electron-electron resonance (DEER) can elucidate the distance
Daniel Klose, Johann P Klare, Dina Grohmann, Christopher W M Kay, Finn Werner, Heinz-Jürgen Steinhoff   +5 more
doaj   +1 more source

Arterial spin labeling in neuroimaging

World Journal of Radiology, 2010
Arterial spin labeling (ASL) is a magnetic resonance imaging technique for measuring tissue perfusion using a freely diffusible intrinsic tracer. As compared with other perfusion techniques, ASL offers several advantages and is now available for routine clinical practice in many institutions. Its noninvasive nature and ability to quantitatively measure
Sasitorn, Petcharunpaisan, Joana, Ramalho, Mauricio, Castillo   +2 more
openaire   +2 more sources

Glass-forming property of hydroxyectoine is the cause of its superior function as a desiccation protectant

Frontiers in Microbiology, 2014
We were able to demonstrate that hydroxyectoine, in contrast to ectoine, is a good glass-forming compound. Fourier transform infrared (FTIR) and spin label electron spin resonance (ESR) studies of dry ectoine and hydroxyectoine have shown that the ...
Erwin Arno Galinski, Christoph eTanne, Andrea eMeffert, Elena A. Golovina, Folkert A. Hoekstra   +4 more
doaj   +1 more source

The Influence of Blood and Serum Microenvironment on Spin-Labeled Magnetic Nanoparticles

Magnetism
The investigation and clarification of the properties of surface-functionalized superparamagnetic nanoparticles in a biological environment are key challenges prior to their medical applications.
Tomasz Kubiak
doaj   +1 more source

Structural basis for functional interactions in dimers of SLC26 transporters

Nature Communications, 2019
The SLC26 family of transporters maintains anion equilibria in all kingdoms of life. Here, the authors resolve the structure of an SLC26 dimer embedded in a lipid membrane and characterize it by PELDOR/DEER distance measurements, biochemical studies with
Yung-Ning Chang, Eva A. Jaumann, Katrin Reichel, Julia Hartmann, Dominik Oliver, Gerhard Hummer, Benesh Joseph, Eric R. Geertsma   +7 more
doaj   +1 more source

Décliner pour progresser : 25 stratégies multimédiatiques dans l’édition pour la jeunesse

Strenae, 2011
In order to make progress, children's publishers rely on three key elements: target audiences, brand development, and expanding the label through spin offs/audiovisuals.
Bertrand Ferrier
doaj   +1 more source