Results 41 to 50 of about 325,167 (345)

Prevalence and breed predisposition for thoracolumbar intervertebral disc disease in cats [PDF]

, 2016
Objectives The objective was to evaluate the prevalence and possible breed predilections for thoracolumbar intervertebral disc disease (IVDD) in cats. Methods Medical records and imaging studies of cats diagnosed with thoracolumbar IVDD between January ...
De Decker, S, Volk, H A, Warner, A-S
core   +2 more sources

Targeting the SYVN1-EGFR axis: a breakthrough strategy for TKI-resistant NSCLC

Cell Death and Disease
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death. Currently, molecular targeted therapy remains a crucial approach to the treatment of NSCLC. However, the development of acquired drug resistance poses significant challenges
Xinsheng Xie, Weilai Tong, Yue Xie, Haoxin Jiang, Alan Jiang, Junming Huang, Zhili Liu, Jingjing Yu   +7 more
doaj   +1 more source

Integrated cryopreservation-thawing-transplantation platform for neural stem cell-based spinal cord injury repair

Bioactive Materials
Spinal cord injury (SCI) repair lacks clinically validated restorative therapies. Transplantation of exogenous neural stem cells (NSCs) offers significant potential for therapeutic applications; however, challenges remain, including substantial cell loss,
Jie Ren, Junjin Li, Hongda Wang, Haiwen Feng, Huaying Hao, Junyu Chen, Yuanquan Li, Zhengyu Xu, Chuanhao Li, Wang Jiang, Yan Wang, Xiaoyang Zhang, Xiaomeng Song, Guangzhi Ning, Jun Liang, Shiqing Feng   +15 more
doaj   +1 more source

Leptomeningitis in a person with radiologically isolated syndrome and latent tuberculosis. A case report with implications for clinical research [PDF]

, 2018
A 39-year-old man, followed with serial MRI of CNS for a radiologically isolate syndrome (RIS, a recently described condition considered a subclinical form of MS), was hospitalized for the occurrence of a leptomeningitis. Routine blood tests and contrast
Bozzao, Alessandro, Chiara Buscarinu, Maria, Ferraldeschi, Michela, Fornasiero, Arianna, Ristori, Giovanni, Romano, Andrea, Romano, Silvia, Salvetti, Marco, Teggi, Antonella   +8 more
core   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Phillygenin inhibits neuroinflammation and promotes functional recovery after spinal cord injury via TLR4 inhibition of the NF-κB signaling pathway

Journal of Orthopaedic Translation
Background: Spinal cord injuries (SCIs) trigger a cascade of detrimental processes, encompassing neuroinflammation and oxidative stress (OS), ultimately leading to neuronal damage.
Yu Zhang, Shining Xiao, Fan Dan, Geliang Yao, Shu'e Hong, Jiaming Liu, Zhili Liu   +6 more
doaj   +1 more source

Generalised boundary shift integral for longitudinal assessment of spinal cord atrophy

NeuroImage, 2020
Spinal cord atrophy measurements obtained from structural magnetic resonance imaging (MRI) are associated with disability in many neurological diseases and serve as in vivo biomarkers of neurodegeneration.
Ferran Prados, Marcello Moccia, Aubrey Johnson, Marios Yiannakas, Francesco Grussu, Manuel Jorge Cardoso, Olga Ciccarelli, Sebastien Ourselin, Frederik Barkhof, Claudia Wheeler-Kingshott   +9 more
doaj   +1 more source

Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. [PDF]

, 2006
BackgroundSomatic afferent input to the spinal cord from a peripheral inflammatory site can modulate the peripheral response. However, the intracellular signaling mechanisms in the spinal cord that regulate this linkage have not been defined.
Albani, Salvatore, Boyle, David L, Firestein, Gary S, Hammaker, Deepa, Jones, Toni L, Rosengren, Sanna, Sorkin, Linda, Svensson, Camille I   +7 more
core   +3 more sources

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

FractalSpiNet: Fractal-Based U-Net for Automatic Segmentation of Cervical Spinal Cord and MS Lesions in MRI

IEEE Access
The spinal cord is an important part of the central nervous system, responsible for transmitting nerve signals throughout the body. The cervical spinal cord contains eight nerve bundles located in the neck region of the spinal cord that transmit to the ...
Rukiye Polattimur, Emre Dandil, Mehmet Suleyman Yildirim, Suleyman Ulucay, Utku Senol   +4 more
doaj   +1 more source