Results 51 to 60 of about 125,751 (335)

Modernization of a Large Spinal Cord Injuries and Disorders Registry: The Veterans Administration Experience

open access: yesArchives of Rehabilitation Research and Clinical Translation, 2022
Since the 1990s, Veterans Health Administration (VHA) has maintained a registry of Veterans with Spinal Cord Injuries and Disorders (SCI/Ds) to guide clinical care, policy, and research. Historically, methods for collecting and recording data for the VHA
Jennifer L. Sippel, PhD   +11 more
doaj  

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

High-resolution investigation of spinal cord and spine [PDF]

open access: yesarXiv, 2017
High-resolution non-invasive 3D study of intact spine and spinal cord morphology on the level of complex vascular and neuronal organization is a crucial issue for the development of treatments for the injuries and pathologies of central nervous system (CNS). X-ray phase contrast tomography enables high quality 3D visualization in ex-vivo mouse model of
arxiv  

Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening

open access: yesAdvanced Materials Technologies, EarlyView.
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló   +5 more
wiley   +1 more source

Characterization of traumatic spinal cord injuries: an integrative review of the literature

open access: yesScientific Electronic Archives, 2020
The objective of this study was to know the profile of traumatic spinal cord injuries in Brazil. Thus, was used the integrative review, whose searches were conducted in October 2018, with health descriptors: spinal cord injuries, injuries and injuries ...
F. Maas   +5 more
doaj   +1 more source

Machine Learning Enhanced Multimodal Bioelectronics: Advancement Toward Intelligent Healthcare Systems

open access: yesAdvanced Sensor Research, EarlyView.
This review examines recent advancements in multimodal bioelectronics, emphasizing machine learning integration to enhance functionality. The application of machine learning methodologies improving biosignal processing, device adaptability, and diagnostic accuracy is discussed to introduce Machine Learning enhanced bioelectronics as a pathway toward ...
Myoungjae Oh   +11 more
wiley   +1 more source

Quantifying Performance of Bipedal Standing with Multi-channel EMG [PDF]

open access: yesIROS 2017, 2017
Spinal cord stimulation has enabled humans with motor complete spinal cord injury (SCI) to independently stand and recover some lost autonomic function. Quantifying the quality of bipedal standing under spinal stimulation is important for spinal rehabilitation therapies and for new strategies that seek to combine spinal stimulation and rehabilitative ...
arxiv  

Bridging spinal cord injuries [PDF]

open access: yesJournal of Biology, 2008
One strategy for spinal cord injury repair is to make cellular bridges that support axon regeneration. However, the bridging cells often fail to integrate with host tissue and may lead to increased pain sensitivity. Recent work has tested bridging with two forms of progenitor-derived astrocyte.
openaire   +4 more sources

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

open access: yesAdvanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou   +7 more
wiley   +1 more source

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