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Spinal Cord injury (SCI) is one of the most devastating and demoralizing ailment for both the patient and the medical practitioner. However, with the better understanding of the pathophysiology, better imaging modalities and emphasis on immobilization and rehabilitation has provided a ray of hope to such patients.
SM Sudambrekar, M Malhotra, HS Bhatoe
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Traumatic spinal cord injury [PDF]
Traumatic spinal cord injury (SCI) has devastating consequences for the physical, social and vocational well-being of patients. The demographic of SCIs is shifting such that an increasing proportion of older individuals are being affected. Pathophysiologically, the initial mechanical trauma (the primary injury) permeabilizes neurons and glia and ...
Jefferson R. Wilson+7 more
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Pyroptosis in spinal cord injury
Spinal cord injury (SCI) often brings devastating consequences to patients and their families. Pathophysiologically, the primary insult causes irreversible damage to neurons and glial cells and initiates the secondary damage cascade, further leading to inflammation, ischemia, and cells death.
Jian Yin+4 more
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Biomarkers in spinal cord injury [PDF]
Literature review.In traumatic spinal cord injury (SCI), much effort has been put into the evaluation of SCI severity and the prediction of recovery potential. An accurate prediction of the initial damage of the spinal cord that differentiates between the severities of SCI however, may help physicians in choosing a particular neuroprotective treatment ...
Pouw, Martin+5 more
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Bridging spinal cord injuries [PDF]
One strategy for spinal cord injury repair is to make cellular bridges that support axon regeneration. However, the bridging cells often fail to integrate with host tissue and may lead to increased pain sensitivity. Recent work has tested bridging with two forms of progenitor-derived astrocyte.
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Rehabilitation of spinal cord injuries
Spinal cord injury (SCI) is the injury of the spinal cord from the foramen magnum to the cauda equina which occurs as a result of compulsion, incision or contusion. The most common causes of SCI in the world are traffic accidents, gunshot injuries, knife injuries, falls and sports injuries.
Nas, Kemal+4 more
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Spinal Cord Stimulation for Spinal Cord Injury
Spinal cord injury is a medically complex and life-disrupting condition, associated with very high mortality rates (early death rates after admission range from 4 to 20%). In addition, it’s complicated subsequent severe disability due to the development of early or late complications.
Emil, Isagulyan,+2 more
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OLD INJURIES OF THE SPINAL CORD [PDF]
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Unlike those in the periphery, nerve fibers in the central nervous system (brain and spinal cord) do not recover from traumatic injury. This makes disabilities from spinal cord damage permanent, with the severity depending on the location of the cord injury.
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