Results 31 to 40 of about 732,175 (355)

Neurotropin exerts neuroprotective effects after spinal cord injury by inhibiting apoptosis and modulating cytokines

open access: yesJournal of Orthopaedic Translation, 2021
Background/objective: Spinal cord injury (SCI) severely and irreversibly damages the central nervous system. Neurotropin (NTP), a nonprotein extract obtained from inflamed rabbit skin inoculated with vaccinia virus, is a drug that has been used for more ...
Xue Yao   +13 more
doaj   +1 more source

Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury [PDF]

open access: yes, 2017
Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal
Birenbaum, Nathan K   +2 more
core   +3 more sources

Preserved gait kinematics during controlled body unloading

open access: yesJournal of NeuroEngineering and Rehabilitation, 2017
Background Body weight supported locomotor training was shown to improve walking function in neurological patients and is often performed on a treadmill.
L. Awai   +5 more
doaj   +1 more source

Origins of Neural Progenitor Cell-Derived Axons Projecting Caudally after Spinal Cord Injury. [PDF]

open access: yes, 2019
Neural progenitor cells (NPCs) transplanted into sites of spinal cord injury (SCI) extend large numbers of axons into the caudal host spinal cord. We determined the precise locations of neurons in the graft that extend axons into the caudal host spinal ...
Anil, Selin   +7 more
core   +1 more source

Investigation of perfusion impairment in degenerative cervical myelopathy beyond the site of cord compression

open access: yesScientific Reports, 2023
The aim of this study was to determine tissue-specific blood perfusion impairment of the cervical cord above the compression site in patients with degenerative cervical myelopathy (DCM) using intravoxel incoherent motion (IVIM) imaging.
Anna Lebret   +8 more
doaj   +1 more source

Limited Functional Effects of Subacute Syngeneic Bone Marrow Stromal Cell Transplantation after Rat Spinal Cord Contusion Injury

open access: yesCell Transplantation, 2016
Cell transplantation might be one means to improve motor, sensory, or autonomic recovery after traumatic spinal cord injury (SCI). Among the different cell types evaluated to date, bone marrow stromal cells (BMSCs) have received considerable interest due
Beatrice Sandner   +5 more
doaj   +1 more source

The localization of molecularly distinct microglia populations to Alzheimer's disease pathologies using QUIVER

open access: yesActa Neuropathologica Communications, 2023
New histological techniques are needed to examine protein distribution in human tissues, which can reveal cell shape and disease pathology connections.
Ryan K. Shahidehpour   +5 more
doaj   +1 more source

Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury. [PDF]

open access: yes, 2019
AimThe activation of the TNFR2 receptor is beneficial in several pathologies of the central nervous system, and this study examines whether it can ameliorate the recovery process following spinal cord injury.MethodsEHD2-sc-mTNFR2 , an agonist specific ...
Bethea, John R   +10 more
core   +2 more sources

Ulnar nerve integrity predicts 1-year outcome in cervical spinal cord injury

open access: yesNeurological Research and Practice, 2019
Background Accurate predictors of neurological recovery after cervical spinal cord injury are needed. Particularly, to tailor adequate rehabilitation plans. However, objective and quantifiable predictors are sparse.
Andreas Hug   +6 more
doaj   +1 more source

Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2

open access: yesNature Neuroscience, 2020
Tissue repair after spinal cord injury requires the mobilization of immune and glial cells to form a protective barrier that seals the wound and facilitates debris clearing, inflammatory containment and matrix compaction. This process involves corralling,
Xiang Zhou   +11 more
semanticscholar   +1 more source

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