Results 31 to 40 of about 240,345 (205)

Epidemic Preventive Management during the Coronavirus Disease 2019 Pandemic Is a Risk Factor for Delirium after Spinal Cord Injury Surgery

Spine Surgery and Related Research, 2023
Introduction: Epidemic preventive management during the coronavirus disease 2019 (COVID-19) pandemic may have negatively impacted perioperative outcomes in patients with traumatic spinal cord injury (SCI).
Hiroki Ushirozako, Kota Suda, Satoko Matsumoto Harmon, Miki Komatsu, Masahiro Ota, Tomoaki Shimizu, Akio Minami, Masahiko Takahata, Norimasa Iwasaki, Yukihiro Matsuyama   +9 more
doaj   +1 more source

Targeting bladder function with network-specific epidural stimulation after chronic spinal cord injury

Scientific Reports, 2022
Profound dysfunctional reorganization of spinal networks and extensive loss of functional continuity after spinal cord injury (SCI) has not precluded individuals from achieving coordinated voluntary activity and gaining multi-systemic autonomic control ...
April N. Herrity, Sevda C. Aslan, Samineh Mesbah, Ricardo Siu, Karthik Kalvakuri, Beatrice Ugiliweneza, Ahmad Mohamed, Charles H. Hubscher, Susan J. Harkema   +8 more
doaj   +1 more source

Spinal Cord Epidural Stimulation Improves Lower Spine Sitting Posture Following Severe Cervical Spinal Cord Injury

Bioengineering, 2023
Cervical spinal cord injury (SCI) leads to impaired trunk motor control, negatively impacting the performance of activities of daily living in the affected individuals.
Kundan Joshi, Enrico Rejc, Beatrice Ugiliweneza, Susan J. Harkema, Claudia A. Angeli   +4 more
doaj   +1 more source

Delayed administration of nafamostat mesylate inhibits thrombin-mediated blood–spinal cord barrier breakdown during acute spinal cord injury in rats

Journal of Neuroinflammation, 2022
Background Nafamostat mesylate (nafamostat, NM) is an FDA-approved serine protease inhibitor that exerts anti-neuroinflammation and neuroprotective effects following rat spinal cord injury (SCI).
Chenxi Zhao, Tiangang Zhou, Xiaoqing Zhao, Yilin Pang, Wenxiang Li, Baoyou Fan, Ming Li, Xinjie Liu, Lei Ma, Jiawei Zhang, Chao Sun, Wenyuan Shen, Xiaohong Kong, Xue Yao, Shiqing Feng   +14 more
doaj   +1 more source

LRP1 Deficiency Promotes Mitostasis in Response to Oxidative Stress: Implications for Mitochondrial Targeting after Traumatic Brain Injury

Cells, 2023
The brain undergoes oxidative stress and mitochondrial dysfunction following physiological insults such as Traumatic brain injury (TBI), ischemia-reperfusion, and stroke.
Gopal V. Velmurugan, W. Brad Hubbard, Paresh Prajapati, Hemendra J. Vekaria, Samir P. Patel, Alexander G. Rabchevsky, Patrick G. Sullivan   +6 more
doaj   +1 more source

Correlation Analysis Between Magnetic Resonance Imaging-Based Anatomical Assessment and Behavioral Outcome in a Rat Contusion Model of Chronic Thoracic Spinal Cord Injury

Frontiers in Neuroscience, 2022
Although plenty of evidences from preclinical studies have led to potential treatments for patients with spinal cord injury (SCI), the failure to translate promising preclinical findings into clinical advances has long puzzled researchers.
Cong Xing, Cong Xing, Cong Xing, Zeyu Jia, Zeyu Jia, Zeyu Jia, Haodong Qu, Haodong Qu, Haodong Qu, Song Liu, Song Liu, Song Liu, Wang Jiang, Hao Zhong, Hao Zhong, Hao Zhong, Mi Zhou, Mi Zhou, Mi Zhou, Shibo Zhu, Shibo Zhu, Shibo Zhu, Guangzhi Ning, Guangzhi Ning, Guangzhi Ning, Shiqing Feng, Shiqing Feng, Shiqing Feng   +27 more
doaj   +1 more source

Mapping reticulospinal drive across various muscles of the upper and lower extremities

Experimental Physiology
The reticulospinal (RS) system is a fundamental descending pathway involved in human movement control. However, the relative strength of RS projections across different muscles and its specific contributions to distinct movements are poorly understood ...
Antonia Maria Eilfort, Lennart Carlson Neumann, Linard Filli   +2 more
doaj   +1 more source

Progression in translational research on spinal cord injury based on microenvironment imbalance

Bone Research, 2022
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level and imposes a considerable burden on patients, families, and society. Repair of the injured spinal cord has been recognized as a global medical challenge for many
Baoyou Fan, Zhijian Wei, Shiqing Feng
doaj   +1 more source

International surveillance study in acute spinal cord injury confirms viability of multinational clinical trials

BMC Medicine, 2022
Background The epidemiological international landscape of traumatic spinal cord injury (SCI) has evolved over the last decades along with given inherent differences in acute care and rehabilitation across countries and jurisdictions.
Lucie Bourguignon, Bobo Tong, Fred Geisler, Martin Schubert, Frank Röhrich, Marion Saur, Norbert Weidner, Rüdiger Rupp, Yorck-Bernhard B. Kalke, Rainer Abel, Doris Maier, Lukas Grassner, Harvinder S. Chhabra, Thomas Liebscher, Jacquelyn J. Cragg, EMSCI study group, John Kramer, Armin Curt, Catherine R. Jutzeler   +18 more
doaj   +1 more source

Inhibit inflammation and apoptosis of pyrroloquinoline on spinal cord injury in rat [PDF]

, 2021
Qiao Zhou, Hui Jin, Naiqi Shi, Shumei Gao, Xiaoyu Wang, Shunxing Zhu, Meijuan Yan   +6 more
openalex   +1 more source