Results 31 to 40 of about 670,877 (408)

Robotic body weight support enables safe stair negotiation in compliance with basic locomotor principles

Journal of NeuroEngineering and Rehabilitation, 2019
Background After a neurological injury, mobility focused rehabilitation programs intensively train walking on treadmills or overground. However, after discharge, quite a few patients are not able to independently negotiate stairs, a real-world task with ...
M. Bannwart, E. Rohland, C. A. Easthope, G. Rauter, M. Bolliger   +4 more
doaj   +1 more source

The localization of molecularly distinct microglia populations to Alzheimer's disease pathologies using QUIVER

Acta Neuropathologica Communications, 2023
New histological techniques are needed to examine protein distribution in human tissues, which can reveal cell shape and disease pathology connections.
Ryan K. Shahidehpour, Abraham S. Nelson, Lydia G. Sanders, Chloe R. Embry, Peter T. Nelson, Adam D. Bachstetter   +5 more
doaj   +1 more source

Treatment of spinal cord injury with mesenchymal stem cells

Cell & Bioscience, 2020
Background Spinal cord injury (SCI) is the damage to the spinal cord that can lead to temporary or permanent loss of function due to injury to the nerve. The SCI patients are often associated with poor quality of life.
L. L. Liau, Q. H. Looi, Wui Chuen Chia, Thayaalini Subramaniam, M. Ng, J. Law   +5 more
semanticscholar   +1 more source

Microdialysis to optimize cord perfusion and drug delivery in spinal cord injury. [PDF]

, 2016
OBJECTIVE: There is lack of monitoring from the injury site to guide management of patients with acute traumatic spinal cord injury. Here we describe a bedside microdialysis monitoring technique for optimizing spinal cord perfusion and drug delivery at ...
Abrahamsson, Abrahamsson, Balis, Bernards, Bracken, Bracken, Carpenter, Casha, Dahyot-Fizelier, Fehlings, Fehlings, Frasca, Hutchinson, Hutchinson, Inoue, Kitagawa, Kobayakawa, Lee, Okon, Papadopoulos, Phang, Phang, Phang, Phang, Plock, Quan, Saadoun, Saadoun, Shannon, Timofeev, Vandenabeele, Varsos, Walters, Werndle, Werndle, Werndle   +35 more
core   +1 more source

Preserved gait kinematics during controlled body unloading

Journal of NeuroEngineering and Rehabilitation, 2017
Background Body weight supported locomotor training was shown to improve walking function in neurological patients and is often performed on a treadmill.
L. Awai, M. Franz, C. S. Easthope, H. Vallery, A. Curt, M. Bolliger   +5 more
doaj   +1 more source

Investigation of perfusion impairment in degenerative cervical myelopathy beyond the site of cord compression

Scientific Reports, 2023
The aim of this study was to determine tissue-specific blood perfusion impairment of the cervical cord above the compression site in patients with degenerative cervical myelopathy (DCM) using intravoxel incoherent motion (IVIM) imaging.
Anna Lebret, Simon Lévy, Nikolai Pfender, Mazda Farshad, Franziska C. S. Altorfer, Virginie Callot, Armin Curt, Patrick Freund, Maryam Seif   +8 more
doaj   +1 more source

Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury. [PDF]

, 2019
AimThe activation of the TNFR2 receptor is beneficial in several pathologies of the central nervous system, and this study examines whether it can ameliorate the recovery process following spinal cord injury.MethodsEHD2-sc-mTNFR2 , an agonist specific ...
Bethea, John R, Blumenthal, Gary H, Bracchi-Ricard, Valerie, Fischer, Roman, Gerald, Marcus J, Kontermann, Roland E, Moxon, Karen A, Nandakumar, Bharadwaj, Pfizenmaier, Klaus, Ricard, Jerome, Williams, Raushaun   +10 more
core   +2 more sources

Neural stem cells in the spinal cord : identity, function and potential [PDF]

, 2021
A large body of work has been dedicated to understanding and remedying the pathological processes that take place after spinal cord injury. Despite these efforts, treatment options are limited and patients with spinal cord injury are left with life-long ...
Stenudd, Moa
core   +1 more source

Limited Functional Effects of Subacute Syngeneic Bone Marrow Stromal Cell Transplantation after Rat Spinal Cord Contusion Injury

Cell Transplantation, 2016
Cell transplantation might be one means to improve motor, sensory, or autonomic recovery after traumatic spinal cord injury (SCI). Among the different cell types evaluated to date, bone marrow stromal cells (BMSCs) have received considerable interest due
Beatrice Sandner, Mareva Ciatipis, Melanie Motsch, Irina Soljanik, Norbert Weidner, Armin Blesch Ph.D.   +5 more
doaj   +1 more source

Alternating current stimulation promotes neurite outgrowth and plasticity in neurons through activation of the PI3K/AKT signaling pathway

Acta Biochimica et Biophysica Sinica, 2023
As a commonly used physical intervention, electrical stimulation (ES) has been demonstrated to be effective in the treatment of central nervous system disorders.
Zhong Hao, Xing Cong, Zhou Mi, Jia Zeyu, Liu Song, Zhu Shibo, Li Bo, Yang Hongjiang, Ma Hongpeng, Wang Liyue, Zhu Rusen, Qu Zhigang, Ning Guangzhi   +12 more
doaj   +1 more source