Results 51 to 60 of about 670,877 (408)

Targeting bladder function with network-specific epidural stimulation after chronic spinal cord injury

Scientific Reports, 2022
Profound dysfunctional reorganization of spinal networks and extensive loss of functional continuity after spinal cord injury (SCI) has not precluded individuals from achieving coordinated voluntary activity and gaining multi-systemic autonomic control ...
April N. Herrity, Sevda C. Aslan, Samineh Mesbah, Ricardo Siu, Karthik Kalvakuri, Beatrice Ugiliweneza, Ahmad Mohamed, Charles H. Hubscher, Susan J. Harkema   +8 more
doaj   +1 more source

LRP1 Deficiency Promotes Mitostasis in Response to Oxidative Stress: Implications for Mitochondrial Targeting after Traumatic Brain Injury

Cells, 2023
The brain undergoes oxidative stress and mitochondrial dysfunction following physiological insults such as Traumatic brain injury (TBI), ischemia-reperfusion, and stroke.
Gopal V. Velmurugan, W. Brad Hubbard, Paresh Prajapati, Hemendra J. Vekaria, Samir P. Patel, Alexander G. Rabchevsky, Patrick G. Sullivan   +6 more
doaj   +1 more source

Traumatic Spinal Cord Injury—Repair and Regeneration

Neurosurgery, 2017
BACKGROUND Traumatic spinal cord injuries (SCI) have devastating consequences for the physical, financial, and psychosocial well-being of patients and their caregivers.
Christopher S Ahuja, Satoshi Nori, Lindsay A. Tetreault, Jefferson R. Wilson, B. Kwon, J. Harrop, D. Choi, M. Fehlings   +7 more
semanticscholar   +1 more source

Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury

Brain : a journal of neurology, 2020
In spinal cord injury, the initial mechanical insult may be followed by progressive cord atrophy and neurodegeneration. Zrzavy et al. characterize innate and adaptive inflammatory responses in human spinal cord injury, and show that oxidative injury is a
T. Zrzavy, C. Schwaiger, I. Wimmer, T. Berger, J. Bauer, O. Butovsky, J. Schwab, H. Lassmann, R. Höftberger   +8 more
semanticscholar   +1 more source

Iatrogenic Spinal Cord Injury Resulting From Cervical Spine Surgery. [PDF]

, 2017
STUDY DESIGN: Retrospective cohort study of prospectively collected data. OBJECTIVE: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery.
Arnold, Paul M., Buser, Zorica, Currier, Bradford L., Daniels, Alan H., Fehlings, Michael G., Fish, David E., Hart, Robert A., Hilibrand, Alan S., Lord, Elizabeth L., Mroz, Thomas E., Nassr, Ahmad, Riew, K. Daniel, Sebastian, Arjun S., Stroh, D. Alex, Tortolani, P. Justin, Wang, Jeffrey C.   +15 more
core   +2 more sources

Feasibility of visual instrumented movement feedback therapy in individuals with motor incomplete spinal cord injury walking on a treadmill

Frontiers in Human Neuroscience, 2014
Background: Incomplete spinal cord injury (iSCI) leads to motor and sensory deficits. Even in ambulatory persons with good motor function an impaired proprioception may result in an insecure gait.
Daniel eSchließmann, Christian eSchuld, Matthias eSchneiders, Steffen eDerlien, Maria eGlöckner, Till eGladow, Norbert eWeidner, Rüdiger eRupp   +7 more
doaj   +1 more source

Correlation Analysis Between Magnetic Resonance Imaging-Based Anatomical Assessment and Behavioral Outcome in a Rat Contusion Model of Chronic Thoracic Spinal Cord Injury

Frontiers in Neuroscience, 2022
Although plenty of evidences from preclinical studies have led to potential treatments for patients with spinal cord injury (SCI), the failure to translate promising preclinical findings into clinical advances has long puzzled researchers.
Cong Xing, Cong Xing, Cong Xing, Zeyu Jia, Zeyu Jia, Zeyu Jia, Haodong Qu, Haodong Qu, Haodong Qu, Song Liu, Song Liu, Song Liu, Wang Jiang, Hao Zhong, Hao Zhong, Hao Zhong, Mi Zhou, Mi Zhou, Mi Zhou, Shibo Zhu, Shibo Zhu, Shibo Zhu, Guangzhi Ning, Guangzhi Ning, Guangzhi Ning, Shiqing Feng, Shiqing Feng, Shiqing Feng   +27 more
doaj   +1 more source

Recovery of Over‐Ground Walking after Chronic Motor Complete Spinal Cord Injury

New England Journal of Medicine, 2018
Persons with motor complete spinal cord injury, signifying no voluntary movement or sphincter function below the level of injury but including retention of some sensation, do not recover independent walking. We tested intense locomotor treadmill training
C. Angeli, M. Boakye, Rebekah A Morton, Justin Vogt, Kristin Benton, Yangsheng Chen, Christie K. Ferreira, S. Harkema   +7 more
semanticscholar   +1 more source

Fecal transplant prevents gut dysbiosis and anxiety-like behaviour after spinal cord injury in rats

PLoS ONE, 2020
Secondary manifestations of spinal cord injury beyond motor and sensory dysfunction can negatively affect a person’s quality of life. Spinal cord injury is associated with an increased incidence of depression and anxiety; however, the mechanisms of this ...
Emma K A Schmidt, Abel Torres-Espín, Pamela J F Raposo, K. Madsen, Kristina A. Kigerl, P. Popovich, Keith K Fenrich, K. Fouad   +7 more
semanticscholar   +1 more source

Minimum toe clearance: probing the neural control of locomotion

Scientific Reports, 2017
Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance
Tim Killeen, Christopher S. Easthope, László Demkó, Linard Filli, Lilla Lőrincz, Michael Linnebank, Armin Curt, Björn Zörner, Marc Bolliger   +8 more
doaj   +1 more source