Results 61 to 70 of about 506,543 (349)

Анализ отечественного и зарубежного опыта в разработке инновационной стратегии [PDF]

, 2005
The purpose of this study was to investigate if functional activity with spinal cord somatosensory stimulation can be visualized using BOLD fMRI. We investigated nine healthy volunteers using a somatosensory stimulus generator.
Krings, T., Möller-Hartmann, W., Pettersson, L. G., Schoth, F., Stracke, C. P.   +4 more
core   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Triple leads with longitudinal guarded cathodes in spinal cord stimulation-effect of transversal lead separation [PDF]

, 2009
In spinal cord stimulation (SCS) clinical practice, longitudinal guarded cathode stimulation by a single lead, placed on the spinal cord midline provides the broadest parasthesia coverage.
Buitenweg, J.R., Holsheimer, J., Sankarasubramanian, V   +2 more
core   +1 more source

Perception threshold and electrode position for spinal cord stimulation [PDF]

, 1994
The perception threshold for epidural spinal cord stimulation in chronic pain management was analyzed on 3923 testing data obtained from 136 implanted patients.
Barolat, Giancarlo, He, Jiping, Holsheimer, Jan, Struijk, Johannes J.   +3 more
core   +3 more sources

A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds

Advanced Healthcare Materials, EarlyView.
Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico, Irene Chiesa, Angela Toffano, Alessio Esposito, Piera Mancini, Chiara Magliaro, Angeliki Louvi, Carmelo De Maria, Marco Onorati   +8 more
wiley   +1 more source

Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]

, 1983
Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor, Bennett, Cervero, Cervero, Cervero, Cervero, Coggeshall, Coggeshall, Dhanjal, Dhanjal, Dubuisson, Fry, Hentall, Hunt, Hökfelt, Kumazawa, Kumazawa, Light, Miletic, Murase, Price, Ruda, Sumal, W. Zieglgänsberger, Wall, Wall, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +29 more
core   +1 more source

Battery‐Free Dual‐Channel Wireless Neurostimulator Using Passive Circuitry for Neuropathic Pain Modulation

Advanced Healthcare Materials, EarlyView.
A compact, wireless neural stimulator featuring a novel tapping inductor enables selective and independent stimulation of the motor cortex in rats via a single receiver coil. This minimally invasive system effectively reduces neuropathic pain through targeted cortical activation, offering a new avenue for bioelectronic pain therapies and advancing ...
Jeongju Moon, Kyungmo Seong, Hyeon Gyu Kim, Wonki Mun, Seung Hyun Min, Sung‐Yun Park, Joonsoo Jeong, Chin Su Koh, Hyun Ho Jung, Kyungsik Eom   +9 more
wiley   +1 more source

Impaired transmission in the corticospinal tract and gait disability in spinal cord injured persons [PDF]

, 2010
Rehabilitation following spinal cord injury is likely to depend on recovery of corticospinal systems. Here we investigate whether transmission in the corticospinal tract may explain foot drop (inability to dorsiflex ankle) in persons with spinal cord ...
Barthélemy, Dorothy, Barthélemy, Dorothy, Biering-Sørensen, Fin, Biering-Sørensen, Fin, Conway, Bernard A, Conway, Bernard A., Holm-Nielsen, Jens Bo, Knudsen, Hanne, Knudsen, Hanne, Lundell, Hans Magnus Henrik, Lundell, Henrik, Nielsen, Jens Bo, Willerslev-Olsen, Maria, Willerslev-Olsen, Maria   +13 more
core   +1 more source

Mechanisms of spinal cord stimulation for the treatment of pain: Still in the dark after 50 years

European Journal of Pain, 2018
Despite the value of spinal cord stimulation (SCS) in treating some patients with focal neuropathic pain, technological advances in stimulator design and treatment protocols have not correlated with significant improvements in clinical outcomes. This may
M. Jensen, R. Brownstone
semanticscholar   +1 more source