Results 1 to 10 of about 260,916 (317)

Comparative intra- and inter-observer reliability of two methods for evaluating intraoperative ultrasonography-based spinal cord hyperechogenicity intensity in degenerative cervical myelopathy

open access: yesBMC Musculoskeletal Disorders, 2022
Objectives During French-door laminoplasty, a linear array transducer of IOUS was used to observe and record the spinal cord decompression. To acquire a higher-reliability method, and compare the in-observer and inter-observer reliability of two methods ...
Huachuan Wu   +6 more
doaj   +1 more source

Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Activation of mitophagy was considered to be a potential therapeutic strategy for intervertebral disc degeneration (IDD). There was evidence suggesting that hyaluronic acid (HA) can protect mitochondria from oxidative stress in chondrocytes, but its ...
Fu Zhang   +11 more
doaj   +1 more source

Characterization of Hemangioblastomas of Spinal Nerves [PDF]

open access: yesNeurosurgery, 2005
Hemangioblastoma is classified as a benign tumor of the central nervous system. Peripheral nervous system hemangioblastomas to date have been described only in a few case reports. Experience in treating patients with these rare lesions, which harbor diagnostic and therapeutic pitfalls, is limited.To characterize these lesions better, we reviewed our ...
Gläsker, Sven   +4 more
openaire   +3 more sources

Effect of mechanical stimulation on tissue heterotopic ossification: an in vivo experimental study

open access: yesFrontiers in Physiology, 2023
Background: Heterotopic ossification of tendons and ligaments (HOTL) is a common clinical condition characterized by the absence of discernible features and a lack of effective treatment. In vitro experiments have demonstrated that mechanical stimulation
Zhengya Zhu   +18 more
doaj   +1 more source

Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis

open access: yesFrontiers in Molecular Biosciences, 2023
Background: Intervertebral disc degeneration (IDD) is the leading cause of lower back pain, and an overall understanding of the molecular mechanisms related to IDD is still lacking. The purpose of this study was to explore gene signatures and immune cell
Tao Tang   +17 more
doaj   +1 more source

Identification of hub genes related to the innate immune response activated during spinal cord injury

open access: yesFEBS Open Bio, 2022
Spinal cord injury (SCI) often leads to sensory and motor dysfunction. Two major factors that hinder spinal cord repair are local inflammation and glial scar formation after SCI, and thus appropriate immunotherapy may alleviate damage.
Jianfeng Li   +10 more
doaj   +1 more source

DLX5 regulates the osteogenic differentiation of spinal ligaments cells derived from ossification of the posterior longitudinal ligament patients via NOTCH signaling

open access: yesJOR Spine, 2023
Background Ossification of the posterior longitudinal ligaments (OPLL) is common disorder characterized by heterotopic ossification of the spinal ligaments. Mechanical stimulation (MS) plays an important role in OPLL.
Tao Tang   +13 more
doaj   +1 more source

Identification of immunodiagnostic blood biomarkers associated with spinal cord injury severity

open access: yesFrontiers in Immunology, 2023
Blood always shows some immune changes after spinal cord injury (SCI), and detection of such changes in blood may be helpful for diagnosis and treatment of SCI.
Jianfeng Li   +18 more
doaj   +1 more source

Intradiscal injection for the management of low back pain

open access: yesJOR Spine, 2022
Low back pain (LBP) is a common clinical problem and a major cause of physical disability, imposing a prominent socioeconomic burden. Intervertebral disc degeneration (IDD) has been considered the main cause of LBP.
Fu Zhang   +5 more
doaj   +1 more source

Effect of cyclic mechanical loading on immunoinflammatory microenvironment in biofabricating hydroxyapatite scaffold for bone regeneration

open access: yesBioactive Materials, 2021
It has been proven that the mechanical microenvironment can impact the differentiation of mesenchymal stem cells (MSCs). However, the effect of mechanical stimuli in biofabricating hydroxyapatite scaffolds on the inflammatory response of MSCs remains ...
Penghui Zhang   +12 more
doaj   +1 more source

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