Results 71 to 80 of about 534,301 (305)

Spindles are highly heritable as identified by different spindle detectors [PDF]

Sleep, 2020
AbstractStudy ObjectivesSleep spindles, a defining feature of stage N2 sleep, are maximal at central electrodes and are found in the frequency range of the electroencephalogram (EEG) (sigma 11–16 Hz) that is known to be heritable. However, relatively little is known about the heritability of spindles.
Jennifer R. Goldschmied, Philip R. Gehrman, Samuel T. Kuna, Samuel T. Kuna, Karine Lacourse, Allan I. Pack, Greg Maislin, Jacques Delfrate, Magdy Younes, Simon C. Warby, Frances M. Pack, Bethany Staley   +11 more
openaire   +2 more sources

Anaphase B. [PDF]

, 2016
Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid, Civelekoglu-Scholey, Gul, Scholey, Jonathan M   +2 more
core   +2 more sources

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint

Journal of Cell Biology, 2003
The proper segregation of sister chromatids in mitosis depends on bipolar attachment of all chromosomes to the mitotic spindle. We have identified the small molecule Hesperadin as an inhibitor of chromosome alignment and segregation.
Silke Hauf, R. Cole, S. LaTerra, C. Zimmer, G. Schnapp, Rainer Walter, A. Heckel, Jacques van Meel, C. Rieder, J. Peters   +9 more
semanticscholar   +1 more source

Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeast

Nature Communications, 2017
Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein.
Sergio A. Rincon, Adam R. Lamson, R. Blackwell, Viktoriya Syrovatkina, V. Fraisier, A. Paoletti, M. Betterton, P. Tran   +7 more
semanticscholar   +1 more source

`Spindles' in symmetric spaces [PDF]

Journal of the Mathematical Society of Japan, 2006
We study families of submanifolds in symmetric spaces of compact type arising as exponential images of s-orbits of variable radii. Special attention is given to the cases where the s-orbits are symmetric.
openaire   +5 more sources

Monitoring spindle orientation: Spindle position checkpoint in charge [PDF]

Cell Division, 2010
AbstractEvery cell division in budding yeast is inherently asymmetric and counts on the correct positioning of the mitotic spindle along the mother-daughter polarity axis for faithful chromosome segregation. A surveillance mechanism named the spindle position checkpoint (SPOC), monitors the orientation of the mitotic spindle and prevents cells from ...
Ayse Koca Caydasi, Gislene Pereira, Bashar Ibrahim   +2 more
openaire   +4 more sources

Spindle configurations of skew lines

, 2004
We prove a conjecture of Crapo and Penne which characterizes isotopy classes of skew configurations with spindle-structure. We use this result in order to define an invariant, spindle-genus, for spindle-configurations.
Borobia, David Garber, Drobotukhina, Khashin, Khashin, Mazurovskiĭ, Mazurovskiĭ, Roland Bacher, Seidel, Viro, Viro, Zaslavsky   +11 more
core   +2 more sources

Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts [PDF]

, 2001
Oncoprotein 18 (Op18) is a microtubule-destabilizing protein that is negatively regulated by phosphorylation. To evaluate the role of the three Op18 phosphorylation sites in Xenopus (Ser 16, 25, and 39), we added wild-type Op18, a nonphosphorylatable ...
Andersen, Andersen, Arnaud, Bahler, Belmont, Brattsand, Carmena, Cassimeris, Charles, Curmi, Curmi, Desai, Desai, Descombes, Di Paolo, Felix, Gard, Gavet, Gigant, Glover, Golsteyn, Gruss, Hamanaka, Heald, Heald, Heald, Heald, Hirano, Horwitz, Howell, Howell, Hyman, Jourdain, Karaiskou, Kotani, Kumagai, Kumagai, Lane, Larsson, Lawler, Llamazares, Logarinho, Luo, Marklund, Maucuer, McKim, Moutinho-Santos, Murray, Nachury, Nigg, Ohkura, Qian, Qian, Sandaltzopoulos, Sawin, Schubart, Shirayama, Steinmetz, Sunkel, Taagepera, Tournebize, Vernos, Walczak, Wallon, Wianny, Wiese, Wray, Zhang   +67 more
core   +4 more sources

Study on the 2D Equivalent Simulation Model of Bearing and Spindle for Precision Machine Tools

Machines, 2023
Precision spindle and bearings are the key components in precision machine tools. These structures greatly affect the machining accuracy and service life of the machine tools.
Shijun Xiu, Jibo Li, Xiangjun Chen, Yifan Xia, Pei Wang   +4 more
doaj   +1 more source

Afadin orients cell division to position the tubule lumen in developing renal tubules [PDF]

, 2017
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found the F-actin binding protein Afadin is required for lumen continuity in developing renal ...
Brakeman, Paul R., Bryant, David M., Gao, Lei, Hiremath, Chitkale, Long, Blake, Luby-Phelps, Katherine, Marciano, Denise K., Mostov, Keith E., Yang, Zhufeng, Zimmerman, Susan E.   +9 more
core   +2 more sources