Results 71 to 80 of about 412,161 (357)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells. [PDF]

open access: yes, 1990
To investigate the mechanisms of spindle elongation and chromosome separation in the fission yeast Schizosaccharomyces pombe, we have developed an in vitro assay using a temperature-sensitive mutant strain, nuc2.
Cande, WZ   +3 more
core  

Illuminating spindle convex bodies and minimizing the volume of spherical sets of constant width

open access: yes, 2011
A subset of the d-dimensional Euclidean space having nonempty interior is called a spindle convex body if it is the intersection of (finitely or infinitely many) congruent d-dimensional closed balls.
B.V. Dekster   +25 more
core   +2 more sources

Chatter Control by Spindle Speed Variation in High-Speed Milling [PDF]

open access: yes, 2009
High-speed milling operations are often limited by regenerative vibrations. The aim of this paper is to analyze the effect of spindle speed variation on machine tool chatter in high-speed milling. The stability analysis of triangular and sinusoidal shape
Arnaud, Lionel   +3 more
core   +2 more sources

The Phage Nucleus and Tubulin Spindle Are Conserved among Large Pseudomonas Phages

open access: yesCell Reports, 2017
We recently demonstrated that the large Pseudomonas chlororaphis bacteriophage 201φ2-1 assembles a nucleus-like structure that encloses phage DNA and segregates proteins according to function, with DNA processing proteins inside and metabolic enzymes and
Vorrapon Chaikeeratisak   +5 more
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence [PDF]

open access: yes, 1977
Rabbit antibodies against actin and tubulin were used in an indirect immunofluorescence study of the structure of the mitotic spindle of PtK1 cells after lysis under conditions that preserve anaphase chromosome movement. During early prophase there is no
Cande, W. Zacheus   +2 more
core   +5 more sources

Force and the spindle: Mechanical cues in mitotic spindle orientation

open access: yesSeminars in Cell & Developmental Biology, 2014
The mechanical environment of a cell has a profound effect on its behaviour, from dictating cell shape to driving the transcription of specific genes. Recent studies have demonstrated that mechanical forces play a key role in orienting the mitotic spindle, and therefore cell division, in both single cells and tissues.
Nestor-Bergmann, Alexander   +2 more
openaire   +3 more sources

Recent advances in plant kinetochore research

open access: yesFrontiers in Cell and Developmental Biology
Faithful chromosome segregation is crucial for cell division in eukaryotes, facilitated by the kinetochore, a multi-subunit protein complex that connects chromosomes to the spindle microtubules.
Elena Kozgunova, Elena Kozgunova
doaj   +1 more source

Development in intensive orchard systems of cherries in Hungary

open access: yesInternational Journal of Horticultural Science, 2007
High density central leader systems, the so called "spindle trees" are spreading in intensive stone fruit orchards established for hand picking in Hungary.
K. Hrotkó   +3 more
doaj   +1 more source

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