Results 151 to 160 of about 25,078 (240)

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 6, June 2026.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo   +7 more
wiley   +1 more source

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

open access: yesBiological Reviews, Volume 101, Issue 3, Page 1491-1510, June 2026.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman   +4 more
wiley   +1 more source

P2X7 receptors promote atrial remodeling and atrial fibrillation susceptibility via reactive oxygen species‐mediated mitogen‐activated protein kinase signaling activation

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract Atrial fibrillation (AF), the most common clinical arrhythmia, is driven by inflammatory activation and oxidative stress, though precise molecular links remain unclear. This study identifies the P2X7 receptor as a key upstream regulator orchestrating proarrhythmic atrial remodeling through reactive oxygen species (ROS)‐mediated mitogen ...
Lingnan Zhang, Yeran Zhu, Xinshun Gu
wiley   +1 more source

Research On the Load‐Bearing Characteristics of Porous Air Bearings Applied to Ultra‐Precision Spindles

open access: yesEngineering Reports, Volume 8, Issue 6, June 2026.
This study analyzes the load‐bearing characteristics of large‐scale porous graphite air bearings for ultra‐precision spindles using CFD simulations. The results elucidate the effects of key design parameters on static performance, offering a theoretical foundation for optimizing wafer thinning machine components.
Peng Zhang, Yuhang Jia, Hao Liu
wiley   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

open access: yesAdvanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

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