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Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation. [PDF]
Nat CommunSoto-Moreno EJ +13 more
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Mechanics of the spindle apparatus.
Seminars in Cell & Developmental Biology, 2020During mitosis microtubules self-organize to form a bipolar mitotic spindle structure, which positions the sister chromatids on the spindle mid-plane and separates them afterwards. Previous studies have identified many spindle associated proteins.
E. Nazockdast, S. Redemann
semanticscholar +3 more sources
Simultaneous staining of the spindle apparatus and constitutive heterochromatin.
Stain Technology, 1974In nonhypotonically treated mitoses from tissue cultures grown on cover glasses, the constitutive heterochromatin as well as the spindle apparatus can be stained by a Giemsa technique for demonstrating repetitive DNA. Cells were treated with 0.015 M sodium chloride and 0.0015 M sodium citrate at 92 C for about 3 min, then with 03 M sodium chloride and ...
F. Pera
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A gene required for the separation of chromosomes on the spindle apparatus in yeast
Cell, 1986We describe the phenotypes caused by a cold-sensitive lethal mutation (ndc1-1) that defines the NDC1 gene of yeast. Incubation of ndc1-1 at a nonpermissive temperature causes failure of chromosome separation in mitosis but does not block the cell cycle.
James H. Thomas, D. Botstein
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THE MITOTIC SPINDLE APPARATUS OF NEUROSPORA CRASSA
Canadian Journal of Genetics and Cytology, 1971Electron microscopic studies of the sl-327 mutant of Neurospora crassa reveal that somatic nuclear division in hyphlet somatic cells involves a definite spindle apparatus consisting of spindle microtubules terminating at specific loci on the external surface of the nuclear envelope. These loci, termed spindle plaques, have been observed in a variety of
W. V. Winkle, J. Biesele, R. P. Wagner
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Protoplasma, 2005
Microtubules (MTs) are the most prominent structural elements of the spindle apparatus. Consequently they are generally thought to a play a role in the processes of spindle elongation and the autonomous chromosome movements towards the spindle poles in anaphase.
H. Fuge
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Microtubules (MTs) are the most prominent structural elements of the spindle apparatus. Consequently they are generally thought to a play a role in the processes of spindle elongation and the autonomous chromosome movements towards the spindle poles in anaphase.
H. Fuge
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Evaluation of the spindle apparatus of in-vitro matured human oocytes following cryopreservation.
Human Reproduction, 1995The present study was conducted to determine if the cryopreservation of immature human oocytes has a deleterious effect on the meiotic spindle following maturation in vitro. Oocytes were obtained in excess from in-vitro fertilization patients and divided into four groups.
S. Baka +5 more
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Evaluation of the meiotic spindle apparatus in oocytes undergoing intracytoplasmic sperm injection.
Fertility and Sterility, 1995To determine whether intracytoplasmic sperm injection has an adverse effect on the meiotic spindle of oocytes after injection of a sperm into the ooplasm.Hamster oocytes were injected with human sperm (Test group) and evaluated for meiotic spindle and chromosome morphology using immunofluorescent staining.
Y. Asada +3 more
semanticscholar +3 more sources
Biochemical and Biophysical Research Communications, 2023
We previously identified a cell cycle-dependent periodic subcellular distribution of cancer metastasis-associated antigen 1 (MTA1) and unraveled a novel role of MTA1 in inhibiting spindle damage-induced spindle assembly checkpoint (SAC) activation in cancer cells.
Jian Liu +6 more
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We previously identified a cell cycle-dependent periodic subcellular distribution of cancer metastasis-associated antigen 1 (MTA1) and unraveled a novel role of MTA1 in inhibiting spindle damage-induced spindle assembly checkpoint (SAC) activation in cancer cells.
Jian Liu +6 more
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A unique antinuclear antibody staining only the mitotic-spindle apparatus.
New England Journal of Medicine, 1981McCarty Ga +3 more
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