Results 61 to 70 of about 1,861,377 (295)

Oral Spindle Cell Sarcoma: A Rare Case Report and Review of Literature [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Spindle cell lesions of the head and neck region are diverse in nature by means of clinical and biological heterogeneity. Though few lesions are found to be malignant, several others are benign or merely reactive in nature.
Sujatha S Reddy   +4 more
doaj   +1 more source

Structural Design of a Special Machine Tool for Internal Cylindrical Ultrasonic-Assisted Electrochemical Grinding

open access: yesMicromachines, 2023
During the process of internal cylindrical ultrasonic-assisted electrochemical grinding (ICUAECG), both the workpiece and the conductive grinding wheel are rotating, the machining space is closed and narrow, the electrolyte is difficult to spray into the
Xiaosan Ma   +6 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

高速高性能电主轴热态性能分析

open access: yesJixie chuandong, 2011
Based on the power flow model of high speed motorized spindle,by using tribology and electromagnetics theory,the heat rate of bearing and the electromagnetic loss of built-in motor are respectively calculated.Utilizing the heat transfer theory,the ...
毕江涛, 陈小安, 李云松
doaj  

State-of-the-art and key technologies of water lubricated ceramic spindle

open access: yesJournal of Hebei University of Science and Technology, 2018
The concept and characteristics of water-lubricated ceramic spindle are introduced. The development trend and industrial application of water-lubricated ceramic spindle at home and abroad are summarized.
Shuai YAN, Bin LIN, Xiaofeng ZHANG
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Strength Analysis and Optimization of Impact Crusher Spindle

open access: yesJixie chuandong, 2015
The mechanical model of impact crusher spindle under operating condition is established and static strength of spindle dangerous section is checked by the method of mechanics of materials.The spindle deflection and torsional rigidity are calculated to ...
Wang Shunkai   +3 more
doaj  

The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function [PDF]

open access: yes, 2005
During mitosis, the spindle assembly checkpoint (SAC) responds to faulty attachments between kinetochores and the mitotic spindle by imposing a metaphase arrest until the defect is corrected, thereby preventing chromosome missegregation. A genetic screen
Vanoosthuyse, V.   +6 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Investigation into how mitotic spindle checkpoint function is compromised by Sv40 large T antigen. [PDF]

open access: yes, 2005
The viral oncoprotein Simian virus 40 large T antigen (LT) efficiently immortalises primary rodent cells and occasionally transforms them to tumourigenicity.
Lock, Rowena Lesley, Lock, R.L.
core  

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