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Electron Microscopy of Spindle Pole Bodies in Pathogenic Fungi
Nippon Ishinkin Gakkai Zasshi, 2010Morphology and dynamics of the spindle pole bodies (SPBs) in Exophiala dermatitidis and Cryptococcus neoformans were examined by freeze-substitution and serial ultrathin sectioning electron microscopy. The SPBs showed double forms and were located on the nuclear envelope in G1 phase, entered the nuclear membrane or the periphery of nucleus in M phase ...
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Genetic analysis of yeast spindle pole bodies
2001Publisher Summary This chapter discusses the genetic analysis of yeast spindle pole bodies. The chapter explains the concepts and methods for three powerful genetic screens that have been fruitful in yielding spindle pole body (SPB) components: a dosage-dependent suppressor screen, an extragenic suppressor screen, and a synthetic lethal screen.
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Exploring the pole: an EMBO conference on centrosomes and spindle pole bodies
Nature Cell Biology, 2008The centrosome and spindle pole body community gathered for its triennial meeting from 12-16 September, 2008 at EMBL in Heidelberg (Germany).
Sue L. Jaspersen, Tim Stearns
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Yeast spindle pole body proteins
1999Abstract Spindle pole body proteins are a diverse set of low abundance proteins. A large fraction including two of the main structural components, Spc11 Op and Spc42p, have coiled coil regions, Kart p has a transmembrane domain, and Cdc31 p is a calcium-binding calmodulin-like protein.
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Spindle pole body duplication: a model for centrosome duplication?
Trends in Cell Biology, 2000The yeast spindle pole body (SPB) is the functional equivalent of the centrosome and forms the two poles of the mitotic spindle. Before mitosis, both SPBs and centrosomes are present as single copies and must be duplicated to form the bipolar spindle. SPB components have been identified using a combination of biochemistry and genetics, and their role ...
I R, Adams, J V, Kilmartin
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Mini review: Mitosis and the spindle pole body inSaccharomyces cerevisiae
The Journal of Experimental Zoology, 1997Cell duplication is characteristic of life. The coordination of cell growth with cell duplication and, specifically, the ordered steps necessary for this process are termed the cell cycle. Central to this process is the faithful replication and segregation of the chromosomes.
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Microtubule and spindle pole body regulation in the budding yeast mitotic spindle
2023The microtubule organizing center (MTOC) is a specialized structure with a main function in microtubule (MT) nucleation and organization. In higher eukaryotes, the main MTOC is known as the centrosome, and its functional equivalent in yeast is the spindle pole body (SPB).
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