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Genetic analysis of yeast spindle pole bodies

2001
Publisher Summary This chapter discusses the genetic analysis of yeast spindle pole bodies. The chapter explains the concepts and methods for three powerful genetic screens that have been fruitful in yielding spindle pole body (SPB) components: a dosage-dependent suppressor screen, an extragenic suppressor screen, and a synthetic lethal screen.
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THE BUDDING YEAST SPINDLE POLE BODY: Structure, Duplication, and Function

Annual Review of Cell and Developmental Biology, 2004
▪ Abstract  Nucleation of microtubules by eukaryotic microtubule organizing centers (MTOCs) is required for a variety of functions, including chromosome segregation during mitosis and meiosis, cytokinesis, fertilization, cellular morphogenesis, cell motility, and intracellular trafficking.
Mark Winey, Sue L. Jaspersen
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Mini review: Mitosis and the spindle pole body inSaccharomyces cerevisiae

The Journal of Experimental Zoology, 1997
Cell duplication is characteristic of life. The coordination of cell growth with cell duplication and, specifically, the ordered steps necessary for this process are termed the cell cycle. Central to this process is the faithful replication and segregation of the chromosomes.
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Spindle positioning and its impact on vertebrate tissue architecture and cell fate

Nature Reviews Molecular Cell Biology, 2021
Marina Mapelli   +2 more
exaly  

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

Nature Reviews Molecular Cell Biology, 2013
Emily A Foley
exaly  

Mitotic spindle assembly in animal cells: a fine balancing act

Nature Reviews Molecular Cell Biology, 2017
Suzanna L Prosser, Laurence Pelletier
exaly  

The spindle-assembly checkpoint in space and time

Nature Reviews Molecular Cell Biology, 2007
Andrea Musacchio, Maria Giordano
exaly  

The 3Ms of central spindle assembly: microtubules, motors and MAPs

Nature Reviews Molecular Cell Biology, 2009
Michael Glotzer
exaly  

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