Results 71 to 80 of about 29,165 (264)

Chatter control by spindle speed variation in high-speed milling

open access: yes, 2009
High-speed milling operations are often limited by regenerative vibrations. The aim of this paper is to analyze the effect of spindle speed variation on machine tool chatter in high-speed milling. The stability analysis of triangular and sinusoidal shape variations is made numerically with the semi-discretization method.
Seguy, Sébastien   +3 more
openaire   +2 more sources

Spatially Configurable Conformal Sensor Integration on an Ultra‐Fine Metallic Needle for Minimally Invasive Deep‐Tissue Oxygen Monitoring

open access: yesAdvanced Materials Technologies, EarlyView.
A multi‐point oxygen‐sensing ultra‐fine needle (MO‐UFN) is developed by conformally integrating a lithographically patterned flexible electrochemical sensor array onto a clinical acupuncture needle. The platform preserves an approximately 0.3 mm diameter while enabling spatially resolved oxygen profiling along the insertion pathway.
Yeju Seo   +9 more
wiley   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

open access: yesAdvanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao   +27 more
wiley   +1 more source

Development of methods to improve spindle rotation accuracy while maintaining the precision of spindle unit components [PDF]

open access: yesE3S Web of Conferences
Spindle rotation accuracy is a critical factor in ensuring the precision and reliability of CNC machining systems. Even minor deviations in spindle rotation can lead to significant dimensional inaccuracies, surface defects, and increased tool wear ...
Juraev Musurmon   +4 more
doaj   +1 more source

Thermal Modelling of a High Speed Motor Spindle

open access: yesProcedia CIRP, 2012
AbstractThis paper presents a 3D FEM model to predict the thermal behaviour of a high speed motor spindle. This model allows a transient simulation which considers complex boundary conditions like heat sources as well as contact and convective heat transfer between spindle parts. Verification experiments are implemented on a test spindle. Compared with
Uhlmann, E., Hu, J.
openaire   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

open access: yesAdvanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun   +10 more
wiley   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

Dynamic behavior of the horizontal milling and drilling machine spindle assembly with Dynrot software

open access: yesMATEC Web of Conferences, 2017
This article presents research conducted to study the dynamic behavior of the assembly of a horizontal milling CNC machine spindle at the speed of 10 000 rpm and 50 000 rpm.
Căruţaşu Nicoleta Luminiţa   +2 more
doaj   +1 more source

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