Results 51 to 60 of about 1,059,853 (352)

Treewidth via Spined Categories (extended abstract) [PDF]

, 2021
Zoltan A. Kocsis, Benjamin Merlin Bumpus
openalex   +1 more source

Book inequalities

, 2014
Information theoretical inequalities have strong ties with polymatroids and their representability. A polymatroid is entropic if its rank function is given by the Shannon entropy of the subsets of some discrete random variables.
Csirmaz, Laszlo
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Current Strategies in Prevention of Postoperative Infections in Spine Surgery. [PDF]

, 2020
Study Design: Narrative review. Objectives: Postoperative surgical site infections (SSIs) are among the most common acute complications in spine surgery and have a devastating impact on outcomes. They can lead to increased morbidity and mortality as well
Atesok, Kivanc, Gokaslan, Ziya L, Heffernan, Michael J, Papavassiliou, Efstathios, Pittman, Jason, Rajaram, Sakthivel, Sitnikov, Irina, Tanaka, Nobuhiro, Theiss, Steven, Tunmire, Danny, Vaccaro, Alexander   +10 more
core   +1 more source

Activation of tyrosine kinases by mutation of the gatekeeper threonine. [PDF]

, 2008
Protein kinases targeted by small-molecule inhibitors develop resistance through mutation of the gatekeeper threonine residue of the active site. Here we show that the gatekeeper mutation in the cellular forms of c-ABL, c-SRC, platelet-derived growth ...
Azam, Mohammad, Daley, George, Gray, Nathanael, KURIYAN, John, Seeliger, Markus   +4 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Two Episodes of Magnetic Reconnections During a Confined Circular-ribbon Flare

, 2018
We analyze a unique event with an M1.8 confined circular-ribbon flare on 2016 February 13, with successive formations of two circular ribbons at the same location. The flare had two distinct phases of UV and EUV emissions with an interval of about 270 s,
Hou, Yijun, Li, Ting, Yang, Shuhong, Zhang, Jun, Zhang, Qingmin   +4 more
core   +1 more source

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1 [PDF]

, 2016
Brief periods of sleep loss have long-lasting consequences such as impaired memory consolidation. Structural changes in synaptic connectivity have been proposed as a substrate of memory storage.
Abel, Ted, Aton, Sara J., Baillie, George S., Bruinenberg, Vibeke M., Day, Jonathan P., Ferri, Sarah L., Hansen, Rolf T., Havekes, Robbert, Houslay, Miles D., Luczak, Vincent G., Meerlo, Peter, Park, Alan J., Poplawski, Shane G., Radwanska, Kasia, Tudor, Jennifer C.   +14 more
core   +6 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Acoustic Power Absorption and its Relation with Vector Magnetic Field of a Sunspot

, 2010
The distribution of acoustic power over sunspots shows an enhanced absorption near the umbra--penumbra boundary. Earlier studies revealed that the region of enhanced absorption coincides with the region of strongest transverse potential field. The aim of
A. Lagg, B. Pontieu De, B. Pontieu De, B.W. Hindman, B.W. Hindman, B.W. Lites, B.W. Lites, B.W. Lites, D. Berghmans, D. Wang, D.C. Braun, D.C. Braun, D.N. Rachkovsky, D.S. Bloomfield, E.N. Parker, G.B. Scharmer, H. Schunker, H. Zirin, I. Moortel De, J.A. Ionson, J.M. Davila, J.V. Hollweg, K. Ichimoto, K. Langhans, M. Landolfi, M.L. Demidov, P. Venkatakrishnan, P. Venkatakrishnan, P. Venkatakrishnan, P.H. Scherrer, P.S. Cally, R.B. Leighton, R.K. Ulrich, S. Chandrasekhar, S. Gosain, S. K. Mathew, S. Tsuneta, S.K. Mathew, T. Kosugi, T. Tran, W. Unno   +40 more
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