Results 21 to 30 of about 34,560 (199)

The combination of three-dimensional and rotary cell culture system promotes the proliferation and maintains the differentiation potential of rat BMSCs

Scientific Reports, 2017
Bone marrow mesenchymal stem cells (BMSCs) are a good candidate for tissue engineering and clinical application. One of the challenges in its cell therapy is how to quickly obtain an adequate number of seed cells and meanwhile maintain suitable ...
Yilong Tang, Yan Xu, Zhifeng Xiao, Yannan Zhao, Jing Li, Sufang Han, Lei Chen, Bin Dai, Ling Wang, Bing Chen, Hong Wang   +10 more
doaj   +1 more source

Update to the dataset of cerebral ischemia in juvenile pigs with evoked potentials

Scientific Data, 2021
Measurement(s) Abnormal auditory evoked potentials • Abnormality of somatosensory evoked potentials • high frequency oscillations • brain activity Technology Type(s) Electrocorticography • electrothalamography Factor Type(s) anesthesia • analgosedation •
Martin G. Frasch, Bernd Walter, Christoph Anders, Reinhard Bauer   +3 more
doaj   +1 more source

Sa12b-Modified Functional Self-Assembling Peptide Hydrogel Enhances the Biological Activity of Nucleus Pulposus Mesenchymal Stem Cells by Inhibiting Acid-Sensing Ion Channels

Frontiers in Cell and Developmental Biology, 2022
Various hydrogels have been studied for nucleus pulposus regeneration. However, they failed to overcome the changes in the acidic environment during intervertebral disc degeneration.
Letian Han, Letian Han, Ziyu Wang, Haoyu Chen, Haoyu Chen, Jie Li, Shengquan Zhang, Sumei Zhang, Shanzhong Shao, Shanzhong Shao, Yinshun Zhang, Yinshun Zhang, Cailiang Shen, Cailiang Shen, Hui Tao, Hui Tao   +15 more
doaj   +1 more source

PRIMUS: Comprehensive proteomics of mouse intervertebral discs that inform novel biology and relevance to human disease modelling

Matrix Biology Plus, 2021
Mice are commonly used to study intervertebral disc (IVD) biology and related diseases such as IVD degeneration. Discs from both the lumbar and tail regions are used.
Mateusz Kudelko, Peikai Chen, Vivian Tam, Ying Zhang, Oi-Yin Kong, Rakesh Sharma, Tiffany Y.K. Au, Michael Kai-Tsun To, Kathryn S.E. Cheah, Wilson C.W. Chan, Danny Chan   +10 more
doaj   +1 more source

Spatiotemporal and functional characterisation of transient receptor potential vanilloid 4 (TRPV4) in the murine intervertebral disc [PDF]

European Cells & Materials, 2021
The molecular regulators of mechano-transduction in intervertebral disc (IVD) cells are not well understood. The aim of the present study was to characterise the expression and function of the mechano-sensitive ion channel TRPV4 in the IVD.
MKM Kim, R Ramachandran, CA Séguin
doaj   +1 more source

Disorientation effects, circulating small ribonucleic acid, and genetic susceptibility on static postural stability

Heliyon, 2023
Background: Motion Sickness increases risk of performance deficits and safety of flight concerns. The etiology of motion sickness is poorly understood.
Ashley Turner, Michael Markey, Peter Le, Ali Reiter, Cyndy Cox, Stacy Simmons, M.B. Rao, Lorenna Altman, Kermit Davis, Dustin Huber, Jonathan S. Dufour, William Marras, Amit Bhattacharya   +12 more
doaj   +1 more source

Is Minimally Invasive Spine Surgery Also Minimally Pro-Inflammatory? Muscular Markers, Inflammatory Parameters and Cytokines to Quantify the Operative Invasiveness Assessment in Spine Fusion

European Journal of Inflammation, 2014
Over the last decades, minimally invasive surgery (MIS) techniques entered in the surgical routine due to their major advantage in reducing the unnecessary exposure of tissue and, thus, the trauma.
G. Lombardi, D. Grasso, P. Berjano, G. Banfi, C. Lamartina   +4 more
doaj   +1 more source

Gene therapy genetic aspects and possibilities for degenerative diseases of intervertebral disks treatment

Ukrainian Neurosurgical Journal, 2008
At the beginning of 90th past century, due to intensive development of molecular biology and tissue engineering, knowledge accumulation about growth factors influence on the intervertebral disc cells, became possible.
E. G. Pedachenko, K. I. Horbatyuk
doaj   +1 more source

In silico engineering and simulation of RNA interferences nanoplatforms for osteoporosis treating and bone healing promoting

Scientific Reports, 2023
Osteoporosis is a bone condition characterized by reduced bone mineral density (BMD), poor bone microarchitecture/mineralization, and/or diminished bone strength.
Aylar Imanpour, Hanieh Kolahi Azar, Dorna Makarem, Zeinab Nematollahi, Reza Nahavandi, Mohammadreza Rostami, Nima Beheshtizadeh   +6 more
doaj   +1 more source

Low back pain and osteoarthritis pain: a perspective of estrogen

Bone Research, 2023
Low back pain (LBP) is the world’s leading cause of disability and is increasing in prevalence more rapidly than any other pain condition. Intervertebral disc (IVD) degeneration and facet joint osteoarthritis (FJOA) are two common causes of LBP, and both
Huiwen Pang, Shihui Chen, David M. Klyne, David Harrich, Wenyuan Ding, Sidong Yang, Felicity Y. Han   +6 more
doaj   +1 more source