Results 1 to 10 of about 348,318 (186)

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte-Mediated Fibrosis and Protecting Nucleus Pulposus Cells. [PDF]

Adv Sci (Weinh)
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Ma F, Zhao Z, Guo C, Liu Y, Wang Y, Yao D, Lan W, Zhong D, Fan C, He Y, Zhang M, Kong Q, Lin Y.   +12 more
europepmc   +2 more sources

Nucleus Pulposus Resorption Following a Paraspinal Hook-Needle Intervention for Lumbar Disc Herniation: A Case Report. [PDF]

Clin Case Rep
Xiao M, Cai Z, Zhu H, Mou S, Zhu W.
europepmc   +1 more source

Surviving the Nucleus Pulposus Desert: Next-Generation Strategies for Intervertebral Disc Cell Therapy. [PDF]

JOR Spine
Hamidouche T, More N, Lee T, Orr M, Camus A, Purmessur D, Gulbrand SE, Chahine NO, Silverman L, Sheyn D.   +9 more
europepmc   +1 more source

Preconditioning Mesenchymal Stem Cells to Enhance Performance in the Degenerate Nucleus Pulposus. [PDF]

Tissue Eng Part B Rev
Maparu AK, Rajagopal K, Iyer K, Mauck RL, Smith LJ.   +4 more
europepmc   +1 more source

HDAC1 maintains metabolic homeostasis in nucleus pulposus cells via post-translational modification interactions with YBX1. [PDF]

Exp Mol Med
Zhou B, Xia J, Zhang Z, Xu B, Ruan Z, Gao T, You C, Ma F, Zhang Z, Yao T, Gao J, Wang J, Zhang Z, Chen J, Shi S, Cui Y, Shen P, Shen S, Ma J.   +18 more
europepmc   +1 more source

Microplastics in nucleus pulposus tissue of humans revealed by Raman mosaic imaging screening. [PDF]

Sci Rep
Zeng Z, Huang R, Song C, Xiang X, Li Z, Wang Y, Wang Y, Zhu L, Wang X, Li X, Jin S.   +10 more
europepmc   +1 more source

[Expression of Concern] Luteolin suppresses TNF-α-induced inflammatory injury and senescence of nucleus pulposus cells via the Sirt6/NF-κB pathway. [PDF]

Exp Ther Med
Xie T, Yuan J, Mei L, Li P, Pan R.
europepmc   +1 more source

Mechanical Suppression of Sonic Hedgehog Signaling by Nucleus Pulposus Cells Underlies Early Disc Degeneration in Mouse. [PDF]

Cells
Virk S, Shah V, Piprode V, Kemp CM, Alluri H, Vincent KF, Krishnan R, Hong J, Albert TJ, Dahia CL.   +9 more
europepmc   +1 more source

Resveratrol alleviates intervertebral disc degeneration by regulating ferroptosis of nucleus pulposus cells. [PDF]

NPJ Syst Biol Appl
Wang X, Lv J, Zhou D, Cai W, Song C, Fu Z, Liu Z.   +6 more
europepmc   +1 more source

Nuciferine-Loaded Lipid Nanoparticle Microneedles Alleviate Intervertebral Disc Degeneration by Restoring Nucleus Pulposus Cell Homeostasis. [PDF]

Pharmaceutics
Ding Y, Wang G, Wang Y, Tan S, Cai Y.
europepmc   +1 more source