Results 41 to 50 of about 19,939 (253)

The differentiation of annulus fibrosus and nucleus pulposus.

, 2020
(a) The annulus fibrosus, (b) The nucleus pulposus.
Hongxin Zhang (551048), Qian Wang (32718), Yuedan Li (8496018), Ning Liang (3777817), Jing Li (10611), Qian Huang (127640), Tao Yang (184280), Yi Yang (116183), Wei Cao (50866), Renzhi Li (1630813)   +9 more
core   +1 more source

The Relationship between HELQ Expression and Intervertebral Disc Degeneration

Global Spine Journal, 2016
Introduction Degeneration of the intervertebral disc, mainly of nucleus pulposus, is strongly implicated as a cause of low back pain. However, the mechanism of disc degeneration is not clear.
Shanhu Huang, Yu Zhang, Zhili Liu, Jiaming Liu   +3 more
doaj   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

The expression of FOXC2 in human nucleus pulposus tissue.

, 2016
(A) The expression of FOXC2 exhibited significantly higher levels in 4 degenerative nucleus pulposus tissue compared to 4 idiopathic scoliosis nucleus pulposus tissue.
Yi Liu (36759), Zheng Wang (25883), Yong Chen (109188), Changfeng Fu (622226), Feng Xu (89016), Zhigang Qu (2174023), Zhenyu Wang (580934)   +6 more
core   +1 more source

PENETRATION OF CEFOTAXIME INTO INTERVERTEBRAL DISCS REMOVED FROM PATIENTS UNDERGOING DISCECTOMY [PDF]

Basrah Journal of Surgery, 2019
The intervertebral disc is an avascular tissue, and penetration of antibiotics occurs by passive diffusion. Cefotaxime penetration has not been well studied.
Thamer Hamdan, Mohammed hashim, Nazar Haddad, Abdullah Jawad   +3 more
doaj   +1 more source

Biomechanical Effects of Different Sitting Postures and Physiologic Movements on the Lumbar Spine: A Finite Element Study

Bioengineering, 2023
This study used the finite element method(FEM) to investigate how pressure on the lumbar spine changes during dynamic movements in different postures: standing, erect sitting on a chair, slumped sitting on a chair, and sitting on the floor.
Mingoo Cho, Jun-Sang Han, Sungwook Kang, Chang-Hwan Ahn, Dong-Hee Kim, Chul-Hyun Kim, Kyoung-Tae Kim, Ae-Ryoung Kim, Jong-Moon Hwang   +8 more
doaj   +1 more source

Measurement and evaluation of surgical models of spinal fusion in mice, rats, and rabbits

Animal Models and Experimental Medicine, EarlyView.
In this study, spinal fusion models in mice, rats and rabbits are compared and discussed. The results show that after comparing the anatomical structure and the complexity of surgical operation, among the three experimental animals in this study, the rabbit as an experimental animal is superior to the mouse and the rat in the establishment of spinal ...
Jianghong Lu, Yicun Hu, Xin Yao
wiley   +1 more source

A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement [PDF]

, 2016
Nucleus pulposus replacements have been subjected to highly controversial discussions over the last 40 years. Their use has not yet resulted in a positive outcome to treat herniated disc or degenerated disc disease.
Schmocker, Andreas, Pioletti, Dominique, Pioletti, Dominique P, Moser, Christophe, Gantenbein, Benjamin, Schizas, Constantiin, Frauchiger, Daniela Angelika, Frauchiger, Daniela A., Bourban, Pierre-Etienne, Schizas, Constantin, Khoushabi, Azadeh   +10 more
core   +1 more source

Dynamic behavior of the nucleus pulposus within the intervertebral disc loading: a systematic review and meta-analysis exploring the concept of dynamic disc model

Frontiers in Bioengineering and Biotechnology
IntroductionThe dynamic disc model (DDM) is a theoretical framework in spine mechanics that theorizes the behavior of the nucleus pulposus within the intervertebral disc under various loads.
Jean-Philippe Deneuville, Jean-Philippe Deneuville, Jean-Philippe Deneuville, Maxime Billot, Alexandra Cervantes, Sylvain Peterlongo, Martin Meyer, Mezika Kolder, Marie Escande, Mathilde Bourgeois, Adrien Pallot, Adrien Pallot, Romain David, Romain David, Romain David, Manuel Roulaud, Amine Ounajim, Mark Laslett, Mathieu Sarracanie, Najat Salameh, Arnaud Germaneau, Philippe Rigoard, Philippe Rigoard, Philippe Rigoard   +23 more
doaj   +1 more source

Retrieval Practice Through an Integrated Anatomy Laboratory Experience in a Doctor of Physical Therapy Curriculum

Clinical Anatomy, EarlyView.
ABSTRACT Gross anatomy is a foundational first‐year component of Doctor of Physical Therapy (DPT) curriculum, with limited future vertical integration. Retrieval practice and spaced learning to enhance retention are rarely embedded in second‐year DPT coursework.
Christina M. Cuka, Kellie C. Huxel Bliven, Emilio J. Puentedura   +2 more
wiley   +1 more source