Dendritic spines as chemical and electrical compartments : a two-photon imaging study in the hippocampus of the rat [PDF]
Most excitatory synapses are located on small dendritic protrusions called spines. So far, the function of dendritic spines is not fully understood. Imaging experiments have shown that spines can compartmentalize second messengers such as Ca2+.
Müller-Grunditz, Åsa
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Study of dendritic spine compartmentalization : a correlative fluorescence light microscopy-electron microscopy approach [PDF]
Neurons communicate with each other through synapses. Most excitatory synapses contact small protrusions called dendritic spines. Spines are connected to dendrites by a very thin stalk called the “spine neck” which restricts diffusion between the spine ...
Cyprien, Vivien
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Gelsolin : a regulator of postsynaptic actin assembly and AMPA receptor expression [PDF]
Dendritic spines are the postsynaptic contact sites for the majority of excitatory synapses in the brain. Synaptic activity influences the number, shape and motility of dendritic spines and these effects are likely mediated by dynamic actin filaments,
Zhao, Pingwei
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Structure-function analysis on the level of individual synapses [PDF]
Excitatory synapses in the mammalian brain are made on small protrusions of the postsynaptic cell called dendritic spines. Dendritic spines are highly variable in their morphology and in their microanatomy (e.g. presence of subsynaptic organelles). It is
Holbro, Niklaus
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Automated analysis of spine dynamics on live CA1 pyramidal cells [PDF]
Dendritic spines may be tiny in volume, but are of major importance for neuroscience. They are the main receivers for excitatory synaptic connections, and their constant changes in number and in shape reflect the dynamic connectivity of the brain.
Vetter, Thomas +6 more
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The function of Copine 6 in the brain [PDF]
The formation of new or the remodeling of pre-existing synapses is thought to provide the cellular correlate of learning and memory processes. In the mammalian forebrain, the postsynaptic site of most excitatory synapses is located on dendritic spines ...
Reinhard, Judith
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Dendritic cable with active spines: a modeling study in the spike-diffuse-spike framework [PDF]
The spike-diffuse-spike (SDS) model describes a passive dendritic tree with active dendritic spines. Spine-head dynamics is modelled with a simple integrate-and-fire process, whilst communication between spines is mediated by the cable equation. Here we
Lord, Gabriel J. +3 more
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Spine morphology of neurons in the Avian forebrain is affected by rearing conditions [PDF]
Rollenhagen A, Bischof H-J. Spine morphology of neurons in the Avian forebrain is affected by rearing conditions. Behavioral and Neural Biology. 1994;62(2):83-89.An area of the caudal forebrain of male zebra finches, the Archi-Neostriatum caudale (ANC ...
Rollenhagen, Astrid +1 more
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Controlling liquid landscape with 3D-printed spines: A tool for micromanipulation [PDF]
Manipulation of floating objects, whether solid or liquid, spanning from microscopic to mesoscopic sizes, is crucial in various microfluidics and microfabrication applications.
Delens, Megan +2 more
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Signaling in dendritic spines and spine microdomains [PDF]
The specialized morphology of dendritic spines creates an isolated compartment that allows for localized biochemical signaling. Recent studies have revealed complexity in the function of the spine head as a signaling domain and indicate that (1) the spine is functionally subdivided into multiple independent microdomains and (2) not all biochemical ...
Yao, Chen, Bernardo L, Sabatini
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