Results 81 to 90 of about 3,002 (191)

Interaction of Dihydroxy-2-Aminotetralin Derivatives at Sites Labelled With [\u3csup\u3e3\u3c/sup\u3eH]Clonidine, [\u3csup\u3e3\u3c/sup\u3eH]Prazosin and [\u3csup\u3e3\u3c/sup\u3eH]Spiperone in Rat Brain Membranes

, 1984
The interactions of 5,6- and 6,7-dihydroxy derivatives of 2-aminotetralin with [3H]clonidine and [3H]clonidine and [3H]prazosin as well as with [3H]spiperone binding sites in rat cerebral cortex membrane preparations were investigated.
Long, John P., Bhatnagar, Ranbir K., Chatterjee, Tapan K., Cannon, Joseph G.   +3 more
core   +1 more source

Characterization of recombinant human serotonin 5HT1A receptors expressed in Chinese hamster ovary cells. [3H]spiperone discriminates between the G-protein-coupled and -uncoupled forms.

, 1993
5HT1A serotonin (5-hydroxytryptamine) receptors have been characterized by ligand binding in a recombinant Chinese Hamster Ovary cell line expressing the human receptor gene.
Strange, Philip G., Sundaram, H., Newman-Tancredi, A.   +2 more
core  

Pergolide elevation of MHPG sulphate concentration in rat hypothalamus blocked by spiperone and mimicked by other dopamine agonists

, 1985
Pergolide increased the concentration of MHPG sulphate (3-methoxy-4-hydroxy-phenylethylene glycol sulphate) in rat hypothalamus, and the increase was prevented by pretreatment with spiperone, a dopamine antagonist.
Susan K Hemrick-Luecke, Kenneth W Perry, Ray W Fuller, Richard E Toomey   +3 more
core   +1 more source

Specific [³H]spiperone binding sites in the pituitary of rainbow trout (Oncorhynchus mykiss) and goldfish (Carassius auratus)

, 1995
Dopamine, a catecholamine neurohormone, modulates pituitary hormone release in teleost fishes and other vertebrates. The existence and binding parameters of a pituitary dopamine–neuroleptic receptor from trout were examined and compared with those from ...
Robert J. Omeljaniuk
core   +1 more source

Coronal view of peak [¹⁸F]spiperone binding in striatum in cranial and hand dystonia.

, 2014
The location of peak [18F]spiperone binding in striatum is plotted for each dystonic subject by atlas |x| and z coordinates according to which part of the body is affected by dystonia. On average, the peak was 2.1 mm more superior in the hand cramp group
Fredy J. Revilla (521411), Stephen M. Moerlein (521412), Kevin J. Black (3214194), Veeral N. Tolia (521410), Joel S. Perlmutter (279777), Jonathan W. Mink (521409), Abraham Z. Snyder (28745)   +6 more
core   +1 more source

[H-3] Nemonapride And [H-3] Spiperone Label Equivalent Numbers Of D-2 And D-3 Dopamine-Receptors In A Range Of Tissues And Under Different Conditions

, 1995
[H-3]Nemonapride and [H-3]spiperone are very widely used to study dopaminergic systems in vitro and in vivo, but it has been reported that [H-3] nemonapride and [H-3]spiperone give markedly different B-max values for preparations of D-2 dopamine ...
Strange, Philip G., Vile, J.M., Dsouza, U.M.   +2 more
core  

INVIVO BINDING OF SPIPERONE AND N-METHYLSPIPERONE TO DOPAMINERGIC AND SEROTONERGIC SITES IN THE RAT-BRAIN - MULTIPLE MODELING AND IMPLICATIONS FOR PET SCANNING

, 1990
Equilibrium models are derived and applied to in vivo binding of spiperone in the rat brain. The models express the concentration of the ligand in the striatum and frontal cortex as a function of the accumulation in the cerebellum. The models differ with
Swart, J.A.A., Wiegman, T., Vaalburg, W., PAANS, AMJ, Korf, J., SWART, JAA, KORF, J, WIEGMAN, T, VAALBURG, W, Paans, A.M.J., VANDERWERF, JF, Van der Werf, J.F.   +11 more
core  

In vivo binding of spiperone and N-methylspirerone to dopaminergic and serotonergic sites in the rat brain: Multiple modeling and implications for PET scanning

, 1990
Equilibrium models are derived and applied to in vivo binding of spiperone in the rat brain. The models express the concentration of the ligand in the striatum and frontal cortex as a function of the accumulation in the cerebellum. The models differ with
Swart, J.A.A., Wiegman, T., Vaalburg, W., Korf, J., Paans, A.M.J., Van der Werf, J.F.   +5 more
core  

Development of Fluorine-18 Halofluorination and Fluorine-18 Fluoride Ion Displacement Reactions for the Synthesis of Fluorine-18 Labeled Radiopharmaceuticals (Spiperone, Spiroperidol, N-Alkylation, Radioactivity)

, 1986
Two fluorine-18 labeling methods, ('18)F halofluorination and ('18)F fluoride ion displacement reactions, have been developed to assess their potential for labeling molecules with the positron-emitting radionuclide fluorine-18 at the no-carrier-added ...
Chi, Dae Yoon
core  

Studies on the interactions of retinal dopamine with choroidal thickness in the chicken. [PDF]

Graefes Arch Clin Exp Ophthalmol, 2023
Mathis U, Feldkaemper M, Liu H, Schaeffel F.   +3 more
europepmc   +1 more source