Results 181 to 190 of about 593,852 (287)

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou   +21 more
wiley   +1 more source

Workspace and trajectory-based experimental validation of a 3-armed 6-DOF parallel robot for femoral fracture surgery. [PDF]

open access: yesFront Robot AI
Gaytan A   +5 more
europepmc   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

Amyloid‐Guided Assembly of Magnetically Recyclable Enzymatic Nanofibers Toward Sustainable Biocatalysis

open access: yesAdvanced Science, EarlyView.
A hierarchical strategy integrates linker engineering, amyloid‐guided self‐assembly, and magnetic immobilization to construct recyclable DPAO4‐DMAO7 enzymatic nanofibers. The resulting magnetic composites enable biogenic amine conversion in complex food matrices and simulated wastewater, while rapid magnetic separation supports repeated reuse. The work
Shuangping Liu   +5 more
wiley   +1 more source

Comparison of Pulmonary Nodule Morphology on Pre-Contrast and Delayed Post-Contrast Stack-of-Spirals Ultrashort Echo Time MRI. [PDF]

open access: yesDiagnostics (Basel)
Fu Q   +9 more
europepmc   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

open access: yesAdvanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo   +12 more
wiley   +1 more source

Stable Magnetic Nanodomains Engineered Via Ga+‐ion Irradiation For Deterministic Sequential Switching

open access: yesAdvanced Electronic Materials, EarlyView.
Tiny magnetic regions separated by domain walls can store data, but controlling them precisely is difficult. We use focused ion beams to create nanoscale “anisotropy wells” that pin these walls from both sides. This bidirectional pinning holds domains stable in either direction, even with no field applied.
Gijs W.A. Simons   +2 more
wiley   +1 more source

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