Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity
Molecules, 2023 Based on the literature data from 1973 to 2022, this work summarizes reports on spiro-flavonoids with a spiro-carbon at the center of their structure and how this affects their isolation methods, stereochemistry, and biological activity.
Łukasz Pecio +3 more
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An Efficient Synthesis and Antibacterial Activity of Some Novel 3,4–Dihydropyrimidin-2-(1H)-Ones
Chemistry Proceedings, 2021 We have efficiently synthesized mono as well as bis and spiro cyclic products of 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) by refluxing a reaction mixture of the three components in deep eutectic solvent (DES) to generating “libraries from libraries ...
Nilesh S. Pawar +2 more
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Scientific Reports, 2023 Spiro[benzo[h]quinoline-7,3′-indoline]diones and spiro[indoline-3,4′-pyrazolo[3,4-b]quinoline]diones were efficiently synthesized via one-pot multi-component reactions under ultrasound-promoted conditions.
Melek Gul +4 more
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Molecules, 2022 Spiro-fused polycyclic aromatic compounds (PACs) have received growing interest as rigid chiral scaffolds. However, furan-containing spiro-fused PACs have been quite limited.
Koji Nakano, Ko Takase, Keiichi Noguchi
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Synthesis and Characterization of a Three Rings Heterocyclic Spiro Furan and Evaluation of its Cytotoxicity Properties on G-292 Cell Lines [PDF]
شیمی کاربردی روز, 2021 Synthesis and study of the medicinal properties of new spiro compounds with various functional groups is of great interest to organic and pharmaceutical researchers because of their special structure and conformation. Multi-component reactions are one of
Mona Besharat +2 more
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A Pinacol Precursor to a Chiral Spiro Compound [PDF]
Acta Crystallographica Section C Crystal Structure Communications, 1996 The dimer of 1-indanolyl obtained from the UV photolysis of 1-indanone in 2-propanol is trans-α,α'-biindanyl-α,α'-diol, (C 9 H 9 O) 2 . There are two almost identical molecules in the asymmetric unit linked by a hydrogen-bonding system that extends along the a axis. Bond distances and angles are as expected.
Schaefer, William P. +3 more
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Synthesis and Characterization of New Spiroheterocyclic from Isatin and Evaluation of Some Their Antifungal and Antibacterial Activity [PDF]
مجلة جامعة الانبار للعلوم الصرفةSpiro compounds Spiro cycles are widely found in natural products, medicines, and functional materials[1] the spiro atom forces the planes of the two rings to almost face one another, spiro compounds are a desirable subclass of heterocyclic scaffolds. In
Zubaida Al-Heety, Ali Al-Nasseri
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Structural and stereogenic properties of spiro- and ansa-substituted 1,3-propanedioxy derivatives of a spermine-bridged cyclotriphosphazene [PDF]
, 2006 Reaction of 1,3-propanediol with the achiral spermine-bridged cyclophosphazene 1 at various molar ratios in THF gives a number of spiro-and ansa-derivatives that exhibit different stereogenic properties, viz. racemic, meso or achiral forms. As expected,
Adem Kılıç +29 more
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Competitive formation of spiro and ansa derivatives in the reactions of tetrafluorobutane-1,4-diol with hexachlorocyclotriphosphazene: a comparison with butane-1,4-diol [PDF]
, 2006 Reaction of hexachlorocyclotriphosphazene, N3P3Cl6 (1), in two stoichiometries (1:1.2 and 1:3) with the sodium derivative of the fluorinated diol, 2,2,3,3-tetrafluorobutane-1,4-diol, (2), in THF solution at room temperature afforded six products, whose ...
Beşli, S. +5 more
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Molecules, 2023 The purpose of this work was to prepare new isatin- and monothiomalondiamide-based indole derivatives, as well as to study the properties of the new compounds.
Victor V. Dotsenko +5 more
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