Results 21 to 30 of about 11,791 (282)

Novel Rearrangements in the Reactions Directed Toward Preparation of Spiro-N,N-ketals: Reactions of Naphthalene-1,8-diamine with Ninhydrin and Isatin

Molecules, 2012
Spiro-N,N-ketal 5, consisting of a phthaloperine heterocyclic ring and a naphtha[1,8-ef][1,4]diazepine ring, was obtained along with spiro-N,N-ketal 2 via 2,2-condensation in the reaction of ninhydrin with naphthalene-1,8-diamine.
Keiji Kobayashi, Junko Kimura, Reiko Aoyama, Hideyuki Seto, Motoko Akita   +4 more
doaj   +1 more source

The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles

Molecules, 2005
The tert-amino reaction effect was examined. A new method to synthesize spiro heterocycles is presented. It was shown that the “tert-amino effect” could be applied to the formation of spiro-fused heterocycles.
Y. Morzherin, O. Eltsov, L. Dyudya, T. Glukhareva, E. D’yachenko   +4 more
doaj   +1 more source

Synthesis and evaluation of the antioxidant activity of new spiro-1,2,4-triazine derivatives applying Ag/Fe3O4/CdO@MWCNT MNCs as efficient organometallic nanocatalysts

Frontiers in Chemistry, 2022
We applied the Petasites hybridus rhizome water extract as green media so that Ag/Fe3O4/CdO@ multi-walled carbon nanotubes magnetic nanocomposites (Ag/Fe3O4/CdO@MWCNTs MNCs) could be prepared.
Elham Ezzatzadeh, Somayeh Soleimani-Amiri, Zinatossadat Hossaini, Khatereh Khandan Barani   +3 more
doaj   +1 more source

Spiro heterocyclic compounds. III. Synthesis of spiro[oxindole-3,4'-(4'H-pyran)] compounds.

Chemical and Pharmaceutical Bulletin, 1980
Die Michaeladdition von CH-aciden Verbindungen (II) bzw. (IV) an die Oxindole (I) fuhrt in einer mehrstufigen Reaktion zu den Spiroverbindungen (III) bzw. (V).
KIMIO HIGASHIYAMA, HIROTAKA OTOMASU
openaire   +2 more sources

Simple approach to thieno[3,2-d]pyrimidines as new scaffolds of antimicrobial activities

Acta Pharmaceutica, 2016
6ʹ-(4-Chlorophenyl)-spiro[cyclohexane-1,2ʹ-thieno[3,2-d][1,3] oxazin]-4ʹ(1ʹH)-one (1) was synthesized and used as a starting material for the synthesis of a novel series of spiro compounds having biologically active sulfonamide 2a-e and 3ʹ-(4 ...
Hafez Hend N., El-Gazzar Abdel-Rhman B. A., Zaki Magdi E. A.   +2 more
doaj   +1 more source

Desing, synthesis and anti-inflammatory activity of dirivatives 10-R-3-aryl-6,7-dihydro-2H-[1,2,4]triazino[2,3-c]quinazolin-2-ones of spiro-fused cyclic frameworks

Acta Chimica Slovenica, 2017
Present work is devoted to the purposeful search of novel promising anti-inflammatory agents among the insufficiently known 3'-R-10'-R1-spiro[hetaryl-3(4),6'-[1,2,4]triazino[2,3-c]quinazolin]-2'(7'H)-ones.
Oleksandra Kolomoets, Oleksii Voskoboynik, Oleksii Antypenko, Galyna Berest, Inna Nosulenko, Vitaliy Palchikov, Olexandr Karpenko, Sergiy Kovalenko   +7 more
doaj   +1 more source

Microbial Transformation of neo-Clerodane Diterpenoid, Scutebarbatine F, by Streptomyces sp. CPCC 205437

Frontiers in Microbiology, 2021
Biotransformation of the neo-clerodane diterpene, scutebarbatine F (1), by Streptomyces sp. CPCC 205437 was investigated for the first time, which led to the isolation of nine new metabolites, scutebarbatine F1–F9 (2–10). Their structures were determined
Dewu Zhang, Xiaoyu Tao, Guowei Gu, Yujia Wang, Wenxia Zhao, Wuli Zhao, Yan Ren, Shengjun Dai, Liyan Yu   +8 more
doaj   +1 more source

Synthesis of spiro quasi[1]catenanes and quasi[1]rotaxanes via a templated backfolding strategy

Nature Communications, 2017
Spiro compounds contain two or more rings linked together through one common atom. Here the authors provide a method to backfold both rings, producing spiro quasi[1]catenanes, via a strategy of temporarily linking the linear intermediates with covalent ...
Luuk Steemers, Martin J. Wanner, Martin Lutz, Henk Hiemstra, Jan H. van Maarseveen   +4 more
doaj   +1 more source

(±)-Peniorthoesters A and B, Two Pairs of Novel Spiro-Orthoester en-antiomers With an Unusual 1,4,6-Trioxaspi-ro[4.5]decane-7-One Unit From Penicillium minioluteum

Frontiers in Chemistry, 2018
(±)-Peniorthoesters A and B (±1 and ±2), two pairs of unprecedented spiro-orthoester enantiomers with a 1,4,6-trioxaspiro[4. 5]decane-7-one unit, were obtained from Penicillium minioluteum. Their structures were determined by spectroscopic methods, X-ray
Xiaorui Liu, Chunmei Chen, Yinyu Zheng, Mi Zhang, Qingyi Tong, Junjun Liu, Qun Zhou, Jianping Wang, Zengwei Luo, Hucheng Zhu, Yonghui Zhang   +10 more
doaj   +1 more source

Spiro Cyclohexadienones from the Reaction of Phenolic Enaminone Derivatives with Hypervalent Iodine Reagents

Molecules, 2000
Phenolic enamino compounds, prepared from 2-(4-hydroxyphenyl)-ethylamine and the corresponding β-keto carbonyl compounds, afford spiro cyclohexadienone derivatives on reaction with hypervalent iodine reagents.
Anastasios Varvoglis, Spyros Spyroudis, Ioannis Papoutsis, Anna Asmanidou   +3 more
doaj   +1 more source