Advanced Synthesis &Catalysis, Volume 367, Issue 9, May 6, 2025.Abstract Spirocyclic compounds, particularly spirocyclohexadienones, are important in pharmaceuticals due to their biological activity. In this study, we develop a catalytic cascade oxidative spirocyclization of diarylamines for the rapid access to highly functionalized spirocyclohexadienones. Using commercially available recyclable heterogeneous metal
Kenji Matsumoto +7 more
wiley +1 more source
Quantum chemical and experimental studies on the mechanism of alkylation of beta-dicarbonyl compounds. The synthesis of five and six membered heterocyclic spiro derivatives [PDF]
, 2004 WOS: 000227831900003PubMed ID: 18007493The alkylation of beta-dicarbonyl compounds in a K2CO3/DMSO system was found to afford O- and C-alkylated derivatives, depending on the type of the P-dicarbonyl compound involved. The alkyl derivatives obtained were
Berber, Halil +4 more
core +1 more source
Complete lignocellulose conversion with integrated catalyst recycling yielding valuable aromatics and fuels [PDF]
, 2018 Lignocellulose, the main component of agricultural and forestry waste, harbours tremendous potential as a renewable starting material for future biorefinery practices. However, this potential remains largely unexploited due to the lack of strategies that
Afanasenko, Anastasiia +6 more
core +1 more source
Synthesis of 3-spiroannulated hexahydro-6,8a-epoxyisoquinolines
Mendeleev Communications, 2002 The title compounds were synthesised by the intramolecular [4+2]-cycloaddition of 1-N-furfurylamino-1-allylcyclanes in the presence of acetic anhydride.
Varlamov A.V. +4 more
openaire +3 more sources
メタルナイトレンを用いた quaternary 3-aminooxindole 単位の触媒的不斉構築を鍵とするchartelline類の全合成研究 [PDF]
, 2011 Tohoku ...
佐藤 茂樹
core +1 more source
Asymmetric Ugi 3CR on isatin-derived ketimine: Synthesis of chiral 3,3-disubstituted 3-aminooxindole derivatives [PDF]
, 2014 An efficient Ugi three-component reaction of a preformed chiral ketimine derived from isatin with various isonitrile and acid components has been developed.
A., Silvani +4 more
core +3 more sources
Syntheses of 1,2-annulated and 1-spiroannulated carbohydrate derivatives: Recent developments
Bioorganic & Medicinal Chemistry, 2012 A variety of different strategies has been used for the 1,2-annulation and the 1-spiroannulation of further rings to monosaccharides. This short review presents some recent methods to access such structures involving radical chemistry, cycloadditions, Michael reactions and metal-catalyzed transformations.
Awan, Shahid I., Werz, Daniel B.
openaire +3 more sources
Enantioselective α-Aminophosphonate Functionalization of Indole Ring through an Organocatalyzed Friedel-Crafts Reaction [PDF]
, 2018 Chiral phosphoric acids efficiently catalyze the asymmetric Friedel−Crafts reaction of several indoles with α-iminophosphonates to afford enantioenriched hybrid α-aminophosphonate functionalized indole derivatives.Financial support from the Ministerio
Maestro Burzaco, Aitor +3 more
core +2 more sources
Inhibition of pre-mRNA splicing by small molecules. [PDF]
, 2008 Cellular function is dependent upon the correct translation of genomic information encoded in DNA into functioning products, usually proteins. Prior to protein translation, DNA is transcribed into messenger RNA (mRNA).
core +1 more source
Synthetic approaches towards alkaloids bearing α-tertiary amines [PDF]
, 2016 Alkaloids account for some of the most beautiful and biologically active natural products. Although they are usually classified along biosynthetic criteria, they can also be categorized according to certain structural motifs.
Hager, Anastasia +4 more
core +1 more source