Results 41 to 50 of about 337 (160)
A novel [4 + 1] and [5 + 1] dearomative spiroannulation has been developed by the use of commercial naphthols and phenols with dielectrophiles. Various spirocycles, including spiro[4.5] and spiro[5.5] have been constructed successfully by employing four ...
Dongwei Zhao (14800357) +4 more
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, 2018 A palladium(0)-catalyzed dearomatizing [3+2] spiroannulation of naphthalene-based biaryls with arynes has been developed for the rapid construction of spirofluorene architectures.
Yicong Ge (3838036) +5 more
core +3 more sources
Syntheses of 1,2-annulated and 1-spiroannulated carbohydrate derivatives: Recent developments
Bioorganic & Medicinal Chemistry, 2012 A variety of different strategies has been used for the 1,2-annulation and the 1-spiroannulation of further rings to monosaccharides. This short review presents some recent methods to access such structures involving radical chemistry, cycloadditions, Michael reactions and metal-catalyzed transformations.
Awan, Shahid I., Werz, Daniel B.
openaire +3 more sources
, 2000 A Claisen rearrangement based methodology for spiroannulation of a cyclopentane ring to cyclic precursors and its application in the formal total synthesis of acorones 1 is described.
A Srikrishna +3 more
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Synthesis of Spirolactones Substituted at the Benzylic Position: Studies Toward the Formation of Manumycin Structural Analogs. [PDF]
, 2012 This study was designed to create a series of spirolactone compounds produced through an oxidative spiroannulation reaction, each with a different substituent at the benzylic position.
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, 2019 Described herein is a palladium-catalyzed dearomative annulation of alkyl bromoarenes with internal alkynes. Challenges in this spiroannulation include the chemoselectivity among [2 + 2 + 1], [2 + 2 + 2], and [3 + 2] annulations and the E/Z-selectivity ...
Deping Wang (1992346) +4 more
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, 2022 Dearomatized indole derivatives bearing a C3- or C2-stereocenter exist ubiquitously in natural products and biologically active molecules. Despite remarkable advances in their chemical synthesis, stereoselective and regio-divergent methods are still in a
Lei, Jiao, Dong, Gao
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, 2022 Presented herein is a controllable selective construction of spiro or fused heterocyclic scaffolds through the one-pot cascade reactions of 1-phenylpyrazolidinones with maleimides.
Na Li (6550) +7 more
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International Journal of Chemistry, 2011 This study was aimed at determining the effect, if any, that steric factors may have on the diastereoselectivity in the spiroannulation of simple phenols. A series of phenols bearing different size substituents ortho to the phenolic hydroxyl were synthesized and spiroannulated to the corresponding spiroethers in good to excellent yields (76-94 ...
Guy L Plourde, Lyndia M. Susag
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An expedient route to spirobenzofurans
, 1993 Synthesis of spirobenzofurans via base mediated spiroannulation is ...
Balasubramanian, K. K. +3 more
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