Results 1 to 10 of about 17,686 (257)

A Study on MDA5 Signaling in Splenic B Cells from an Imiquimod-Induced Lupus Mouse Model with Proteomics

open access: yesCells, 2022
Introduction: Several environmental stimuli may influence lupus, particularly viral infections. In this study, we used an imiquimod-induced lupus mouse model focused on the TLR7 pathway and proteomics analysis to determine the specific pathway related to
Yu-Jih Su   +11 more
doaj   +1 more source

Strain-Specific Identification and In Vivo Immunomodulatory Activity of Heat-Killed Latilactobacillus sakei K040706

open access: yesFoods, 2021
We previously reported that the immunostimulatory activity of heat-killed Latilactobacillus sakei K040706 in macrophages and cyclophosphamide (CTX)-treated mice. However, identification of heat-killed L. sakei K040706 (heat-killed LS06) using a validated
Kyung-Sook Chung   +11 more
doaj   +1 more source

Immunocyte Populations Observed from Birth to Weaning in Blood, Spleen and Mesenteric Lymph Nodes of Piglets

open access: yesAnimals, 2022
Susceptibility to pathogen infections and efficacy of vaccination highly depend on the immune status of the piglet. Here, we measured immunocytes in piglets from birth to weaning to elucidate how immunocyte populations change during development and are ...
Tomoko Harayama   +4 more
doaj   +1 more source

Metabolomic Profiling and Immunomodulatory Activity of a Polyherbal Combination in Cyclophosphamide-Induced Immunosuppressed Mice

open access: yesFrontiers in Pharmacology, 2022
The study was aimed to develop a characterized polyherbal combination as an immunomodulator containing Phyllanthus emblica L., Piper nigrum L., Withania somnifera (L.) Dunal, and Tinospora cordifolia (Willd.) Miers.
Sultan Zahiruddin   +9 more
doaj   +1 more source

Antioxidant and Immune-Modulating Activities of Egg Yolk Protein Extracts

open access: yesFood Science of Animal Resources, 2022
Egg yolk is widely used to extract lecithin, which is utilized in the food and cosmetics industry. After lecithin is removed, the rest of egg yolk is generated as a by-product. Thus, it is necessary to properly utilize it. In this study, egg yolk protein
Jae Hoon Lee   +3 more
doaj   +1 more source

Human Leukemia T-Cell Lines as Alternatives to Animal Use for Detecting Biologically Active Staphylococcal Enterotoxin Type B

open access: yesToxins, 2021
Staphylococcal enterotoxin type B (SEB) is associated with food poisoning. Current methods for the detection of biologically active SEB rely upon its ability to cause emesis when administered to live kittens or monkeys.
Reuven Rasooly   +3 more
doaj   +1 more source

Morphine Induces Splenocyte Trafficking into the CNS [PDF]

open access: yesJournal of Neuroimmune Pharmacology, 2011
Opioids significantly alter functional responses of lymphocytes following activation. The opiate Morphine, alters the Th1 to Th2 response and modulates functional responses such as cytolytic activity and T-cell proliferation. Although there has been extensive research involving morphine's effects on lymphocytes, little is known about the effects ...
Michael, Olin   +4 more
openaire   +2 more sources

Antiviral Resistance of Splenocytes in Aged Mice

open access: yesPolish Journal of Microbiology, 2017
Abstract We compared the susceptibility to viral infection of splenocytes, isolated from young versus old CBA mice, and evaluated the antiviral actions of lactoferrin in splenocytes infected with Encephalomyocarditis virus ( EMCV ...
Ewa Zaczyńska   +6 more
openaire   +5 more sources

Nano chloroquine delivery against Plasmodium berghei NK65 induced programmed cell death in spleen

open access: yesAsian Pacific Journal of Tropical Medicine, 2018
Objective: To compare the protective effects of chitosan-trypolyphosphate (CS-TPP) nanoparticle conjugated chloroquine(CQ) with effect of CQ alone on the reversal of splenic damages and induction of apoptosis.
Satyajit Tripathy   +4 more
doaj   +1 more source

Topical Application of KAJD Attenuates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis Symptoms Through Regulation of IgE and MAPK Pathways in BALB/C Mice and Several Immune Cell Types

open access: yesFrontiers in Pharmacology, 2019
Atopic dermatitis (AD) is a frequent skin complication that is caused by unknown reasons. KHU-ATO-JIN-D (KAJD) is a new drug aimed at AD composed of a mixture of extracts from six plants known to have anti-inflammatory and antiallergic effects.
Se Hyang Hong   +6 more
doaj   +1 more source

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