Results 21 to 30 of about 20,678 (288)
Chronic stress leads to immunosuppression and induces splenocyte apoptosis. STAT3 is a transcription factor that regulates immunity and apoptosis; however, it is unclear whether the increased expression of phosphorylated STAT3 (p-STAT3) observed in ...
Manyu Song +6 more
doaj +1 more source
This study assessed the protective effects of selenium-chitosan (SC) against antioxidant and immune function-related damage induced by zearalenone (ZEN) in mice. In total, 150 female mice were allotted to five groups for a 30-day study. Control mice were
Shunyi Qin +4 more
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Staphylococcus aureus is a major bacterial cause of clinical infections and foodborne illnesses through its production of a group of enterotoxins (SEs) which cause gastroenteritis and also function as superantigens to massively activate T cells.
Reuven Rasooly +2 more
doaj +1 more source
Inhibitory Effect of Hydroxymethylfurfural in Viability of BALB/C Mice Splenocytes [PDF]
Background: This study was designed to discover if hydroxymethylfurfural (HMF) exposure modifies cell proliferation and DNA damage in BALB/c mice splenocytes.
Sevda Saleh-Ghadimi +3 more
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Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis [PDF]
In sepsis, both necrotic and apoptotic cell death can occur. Apoptotic cells induce anergy that could impair the host response, whereas necrotic cells cause immune activation that might result in enhanced antimicrobial defenses. We determined whether adoptive transfer of apoptotic or necrotic cells impacted survival in a clinically
Richard S, Hotchkiss +7 more
openaire +2 more sources
Blood form trypomastigotes of the Y strain of T. cruzi, produced a strong inhibition of the blastogenic response to T and B cell mitogens, of the C3H/He, C57BLand BALB/cJ strains of mice, while culture epimastigotes of the Y strain kept in a medium that ...
L. E. Serrano, J. A. O'Daly
doaj +1 more source
Objective: To evaluate the potential immunomodulatory effects of an aqueous extract of Sesamum indicum seeds with regard to splenocyte proliferation, Th1/Th2 balance, macrophage function, and the cytotoxic activity of natural killer (NK) cells.
Amin F Majdalawieh +2 more
doaj +1 more source
Splenocyte immunosuppression assay.
The splenocyte stimulated by LPS (A) or PMA/ionomycin (B) shows decreased proliferation rate when co-cultured with TMSC and cultured in TMSC-CM. Proliferation was significantly reduced by the number of TMSC and the concentration of TMSC-CM.
Chang Mo Moon (8066759) +6 more
core +1 more source
IntroductionSplenocytes are important for various applications in medicine and biotechnology, but isolation methods are often limited by low yield, poor viability, bias towards certain cell subtypes, and degradation of surface marker expression. Here, we
Jeremy A. Lombardo +7 more
doaj +1 more source
Alternative to Animal Use for Detecting Biologically Active Staphylococcal Enterotoxin Type A
Staphylococcal enterotoxins (SEs) are a food safety concern. Existing methods for biologically active SE detection rely on the emetic response in live kittens or monkeys.
Reuven Rasooly +3 more
doaj +1 more source

