Results 11 to 20 of about 20,678 (288)

Regulation of murine splenocyte responses by heparan sulfate

The Journal of Immunology, 1991
Abstract Heparan sulfate is a biologically active glycosaminoglycan found in abundance in endothelium, epithelium, and connective tissues. Although heparan sulfate is an important part of the environment in which immune cells function, its effects on the immune system are largely unknown.
Wrenshall, Lucile E., Cerra, Frank B., Carlson, Ann, Bach, Fritz H., Platt, Jeffrey L.   +4 more
core   +6 more sources

Genipin protects against sepsis via the inhibition of endoplasmic reticulum stress to attenuate splenocyte apoptosis

生物医学转化, 2023
Objective This study is undertaken to elucidate the protective effect and molecular mechanism of genipin against cecal ligation and puncture (CLP)-induced sepsis.
Luo Ning, Chen Guibing, Zhang Teng, Zhao Jie, Fu Jingnan, Lu Ning, Ma Tao   +6 more
doaj   +2 more sources

Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures. [PDF]

PLoS ONE, 2014
The family of sphingosine-1-phosphate receptors (S1PRs) is G-protein-coupled, comprised of subtypes S1PR1-S1PR5 and activated by the endogenous ligand S1P.
Adam J Pritchard, Anis K Mir, Kumlesh K Dev   +2 more
doaj   +2 more sources

Morphine Induces Splenocyte Trafficking into the CNS [PDF]

Journal of Neuroimmune Pharmacology, 2011
Opioids significantly alter functional responses of lymphocytes following activation. The opiate Morphine, alters the Th1 to Th2 response and modulates functional responses such as cytolytic activity and T-cell proliferation. Although there has been extensive research involving morphine's effects on lymphocytes, little is known about the effects ...
Michael, Olin, Seunguk, Oh, Sabita, Roy, Phillip, Peterson, Thomas, Molitor   +4 more
openaire   +2 more sources

Cytokine levels in splenocyte supernatants.

, 2021
Cytokine levels in splenocyte supernatants. Panel A) IFN-γ levels in prophylactic co-vaccinated groups with D1(83–119), D2, B´B and B´BCOOH along IFN-γ and IL-10, PBS and mock treatment.
Flavio Sandoval-García (7359668), Minoru Satoh (23451), Fernanda Isadora Corona-Meraz (7359683), Oscar Pizano-Martinez (10684830), Trinidad García-Iglesias (4436794), Monica Vázquez-Del Mercado (11614204), Beatriz Teresita Martín-Márquez (7359692), Rogelio Hernández-Pando (60614), Erika Aurora Martínez-García (7359677), Marcelo Heron Petri (11614201)   +9 more
core   +1 more source

Collagen-Binding IL-15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self-Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity. [PDF]

Adv Sci (Weinh)
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yang Y, Liu X, Ding J, Xu J, Zhang J, Zhang H, Yang R, Li S, Zheng L, Su R, Zhao Y, Wu J, Li H, Zhan C, Gao X.   +14 more
europepmc   +2 more sources

Antiviral Resistance of Splenocytes in Aged Mice

Polish Journal of Microbiology, 2017
Abstract We compared the susceptibility to viral infection of splenocytes, isolated from young versus old CBA mice, and evaluated the antiviral actions of lactoferrin in splenocytes infected with Encephalomyocarditis virus ( EMCV ...
Ewa Zaczyńska, Jolanta Artym, Maja Kocięba, Timo Burster, Marian Kruzel, Maria Paprocka, Michał Zimecki   +6 more
openaire   +5 more sources

Estrogen selectively regulates chemokines in murine splenocytes [PDF]

Journal of Leukocyte Biology, 2006
AbstractEstrogen has striking effects on immunity and inflammatory autoimmune conditions. One potential mechanism of estrogen-induced regulation of immunity and inflammatory autoimmune conditions is by altering the secretion of chemokines by lymphocytes, an aspect not well addressed thus far. We found that estrogen has marked, but differential, effects
Andrea J, Lengi, Rebecca A, Phillips, Ebru, Karpuzoglu, S Ansar, Ahmed   +3 more
openaire   +2 more sources

L-arginine: A unique amino acid for improving depressed wound immune function following hemorrhage [PDF]

, 2002
Objective: To determine whether L-arginine has any salutary effects on wound immune cell function following trauma-hemorrhage. Background. Depressed wound immune function contributes to an increased incidence of wound infections following hemorrhage ...
Hatz, Rudolf A., Chaudry, Irshad H., Nitsch, Stefan M., Rudolf A. Hatz, Peter Angele, Mathias W. Wichmann, Angele, Peter, Irshad H. Chaudry, Wichmann, Mathias W., Thomas Hernandez-Richter, Schildberg, Friedrich Wilhelm, Martin K. Angele, Stefan M. Nitsch, Schildberg, Friedrich W., Angele, Martin K., Hernandez-Richter, Thomas, Friedrich W. Schildberg   +16 more
core   +1 more source

Splenocyte transfer eliminates premenopausal female protection from Ang II induced hypertension (Supplemental Figures)

, 2022
Supplemental Figure 1: Post-transfer Blood PressuresSupplemental Figure 2: Male Blood PressuresSupplemental Figure 3: CD3+ T cell FrequenciesSupplemental Figure 4: NT T cell transfer F480 IHCSupplemental Figure 5: Splenocyte Transfer F480 and ...
Heddwen Brooks (11404046), Megan Sylvester (11404076)   +1 more
core   +1 more source