Results 111 to 120 of about 20,678 (288)

Intracellular Staining for Phosphorylated STAT4 and STAT5 in Mouse Splenocytes

open access: yesBio-Protocol, 2014
The Stat (Signal Transducer and Activator of Transcription) family of proteins are critical signal transducers involved in fundamental cellular processes, including cell growth and differentiation, development, apoptosis, immune responses and ...
Ana Villegas-Mendez   +8 more
doaj   +1 more source

Effects of Estrogenic Compounds on Immunoglobulin Production by Mouse Splenocytes.

open access: yesBiological and Pharmaceutical Bulletin, 2002
The effects of culture medium and serum components on immunoglobulin (Ig) production by mouse splenocytes were examined. In this study, we showed that culture medium containing charcoal-dextran-treated fetal bovine serum (CDFBS) supported Ig production more efficiently than culture medium containing FBS.
Han, Dalho   +3 more
openaire   +3 more sources

Cytokine production in splenocyte co-cultures.

open access: yes, 2014
Spleen cells were stimulated with LPS in the presence of LET cells and/or retinol. Culture components are indicated below each bar. Cytokines that were reproducibly elevated in the presence of LET cells and retinol are shown, including GM-CSF (Panel A ...
Julia L. Hurwitz (214689)   +5 more
core   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang   +11 more
wiley   +1 more source

Effect of chronic exercise on splenocyte proliferation.

open access: yes, 2019
(A) Representative histograms of cytometric analysis of dividing cells. Two parameters were considered to assess the proliferative capacity of splenocytes: (B) the proliferation index, which did not change due to chronic exercise and (C) the proportion ...
Karen Elizabeth Nava-Castro (6940340)   +5 more
core   +1 more source

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas   +4 more
wiley   +1 more source

Yolkin Ameliorates Effects of the Psychic Stress on the Contact Sensitivity, Cell Proliferation, and Cytokine Production in Mice

open access: yesFrontiers in Bioscience-Landmark
Background: Prolonged psychic stress leads to immune suppression, which preferentially affects the cellular immune response. Yolkin is an egg-derived protein with firmly established immunoregulatory activities in rodent models.
Michał Zimecki   +8 more
doaj   +1 more source

Effect of murine exposure to gamma rays on the interplay between Th1 and Th2 lymphocytes

open access: yesFrontiers in Pharmacology, 2015
Background: Gamma radiation or radiotherapy is one of the most widely used treatments for cancer. There is accumulating evidence that adaptive immunity significantly contributes to the efficacy of radiotherapy.
Amany Abd-Elkader Ghazy   +4 more
doaj   +1 more source

IL-6 supplementation diminishes Tregs in TFA-S100 – immunized male and female splenocyte cultures in vitro.

open access: yes, 2013
IL-6 supplementation (25 ng/mL) of in vitro splenocyte cultures from female (A) and male (B) TFA-S100-immunized BALB/c mice diminished Tregs in both groups.
Joonhee Cho (399792)   +5 more
core   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

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