Results 131 to 140 of about 20,678 (288)
Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1989 To study the cell-mediated link of immune response in mice in experimental influenza, both spleen cells obtained from intact mice and infected with the virus in vitro and spleen cells obtained from infected mice on day 6 after infection may equally be used with success as target cells.
openaire +1 more source
Arthritis &Rheumatology, EarlyView.Objective CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda +5 more
wiley +1 more source
Programmable three‐state nanoreactor for spatiotemporally controlled tumor therapy
BMEMat, EarlyView.The OMVs are shielded with a biocompatible Da–Ca shell, which prolongs its circulation period and promotes intratumoral accumulation. Importantly, the biocompatible Da–Ca shell can be controllably disintegrated in tumor microenvironment by using laser irradiation, generating in situ hyperthermia and releasing Ca2+.
Guihong Lu +12 more
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Cytoflow: User‐Friendly Python Software for Computational Flow Cytometry
Cytometry Part A, EarlyView.ABSTRACT Modern flow cytometry experiments routinely measure 18 or more fluorescent markers across many samples, patients, and tissues. As these experiments' complexity increases, manual gating becomes unacceptably inefficient and can introduce operator‐to‐operator variation. Computational cytometry algorithms such as unsupervised clustering, automated
Leah Teague
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Mediators of Inflammation, 2011 The effects of dietary protein and fat on renal function-related blood and urine parameters, such as albumin, urinary protein,and inflammatory cytokines were investigated in adriamycin- (ADR) induced nephrotic syndrome rats. ADR (2 mg/kg BW) was injected
Su Yeon Kim +4 more
doaj +1 more source
Kinetics of splenocyte interleukin-4 production after injury and lethal endotoxin challenge
, 1997 Cytokine aberrations may contribute to sepsis-associated mortality after trauma. We have previously documented that IL-10 (a Th-2 cytokine) is downregulated after tissue trauma, and the administration of exogenous IL-10 improved survival and anti-IL-10 ...
Campbell, Cara +2 more
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Interdisciplinary Medicine, EarlyView.Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li +15 more
wiley +1 more source
International Journal of Food ScienceThis research demonstrates the in vivo immunomodulatory and hepatoprotective activities of the soluble melanins of the Randia echinocarpa fruit (PSM).
María del Rosario Gil-Avilés +4 more
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Phytotherapy Research, EarlyView.Overview of the antileukemic effects of Piper nigrum extract in AML. P. nigrum reduced leukemic cell proliferation and glycolytic metabolism through modulation of the PI3K/AKT/mTOR pathway. In vivo, treatment reduced leukemic burden, improved hematological parameters, prolonged survival, and modulated antitumor immune responses.
Natalia Murillo +3 more
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Phytotherapy Research, EarlyView.ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta +9 more
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