Results 131 to 140 of about 17,686 (257)

From Parasite to Therapy: Immunomodulatory Effects of a Trichuris trichiura Derived Recombinant Protein in Allergic Airway Disease

Clinical &Experimental Allergy, EarlyView.
Jessica Cristiane da Conceição de Andrade, Eduardo Santos da Silva, Jennifer Emily Anunciação Sousa, Jade Liz Ferreira Mendes Souza, Carolina Melo Orrico‐Ferreira, Lorena Miranda Souza, Raphael Chagas Silva, Silvia Letícia Bispo dos Santos, Antônio Márcio Santana Fernandes, João Vitor Borges Rios, Paulo Emílio Oliveira Cruz, Vítor Lima Miranda Melo, Emília Maria Medeiros de Andrade Belitardo, Luís Gustavo Carvalho Pacheco, Carina Silva Pinheiro   +14 more
wiley   +1 more source

Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress

British Journal of Pharmacology, Volume 183, Issue 16, Page 5102-5119, August 2026.
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan, Rongfang Feng, Mai Luo, Yaqi Wang, Min Gao, Qin Chen, Yufei Zhang, Yale Liu, Yumin Xia   +8 more
wiley   +1 more source

Triiodothyronine-driven pro-inflammatory responses of dendritic cells are restrained by sphingolipid signaling. [PDF]

J Endocrinol
Negretti-Borga DM, Pires Teixeira M, Blanco A, Puentes EN, Soler MF, Alamino VA, Donadio AC, Clarke CJ, Montesinos MDM, Hannun YA, Pellizas CG.   +10 more
europepmc   +1 more source

Experimental Models of Autoimmune Hepatitis: Disease Fidelity and Translational Relevance

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Autoimmune hepatitis (AIH) remains difficult to study mechanistically in patients because disease initiation is rarely observed directly, the relevant autoantigens differ across subsets, and clinically meaningful outcomes such as chronic inflammation, fibrosis, relapse, and treatment response evolve over time.
Laura Elisa Buitrago‐Molina, Matthias Hardtke‐Wolenski   +1 more
wiley   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie, Volume 138, Issue 28, 6 July 2026.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +2 more sources

METTL3-m⁶A-STAT1/NF-κB axis: a key switch for the immunosuppressive capacity of mesenchymal stem cells. [PDF]

Cell Mol Biol Lett
Tang K, Han H, Sun R, Xu Y, Zhang S, Lai C, Peng Y.   +6 more
europepmc   +1 more source

Splenic B Cells Accumulate and Adopt a Pro‐Inflammatory Phenotype to Accelerate Fibrosis in a CCl4‐Induced Liver Fibrosis Model

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Splenic B cells accumulate and adopt pro‐inflammatory phenotype via activation of p38 MAPK/NF‐κB pathway, thereby accelerating CCl₄‐induced hepatic fibrosis. ABSTRACT The spleen plays a significant role in hepatic fibrosis progression. B cells are the main splenic lymphocytes, but their specific contributions and underlying mechanisms remain unclear ...
Keping Feng, Qiaoman Fei, Chongyu Zhang, Junqiao Feng, Ke Du, Na Huang, Xurui Zhang, Zhe Zhou, Chengbo Zhang, Shaoying Zhang, Shemin Lu, Yanying Dong, Guangyao Kong   +12 more
wiley   +1 more source

Immunosuppressive impact of <i>Aedes triseriatus</i> salivary gland extract on lymphocyte biology. [PDF]

Front Immunol
Ring M, Valenzuela Leon PC, Bonilla B, Wu J, Percopo C, Su XZ, Calvo E.   +6 more
europepmc   +1 more source

A First‐In‐Class Antibody Enabling Detection of Altered Peripheral Non‐Phosphorylated Clusterin With Translational Potential in Dementia

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Non‐phosphorylated clusterin is decreased in the serum of dementia patients but not in Parkinson's disease, and phosphorylated clusterin in serum does not originate from the brain. 3D3F10, a monoclonal antibody specific to non‐phosphorylated clusterin, enables modification‐specific detection with diagnostic potential for dementia.
Hejie Li, Yu Li, Wenping Liang, Liyong Wu, Chao Han, Qianxu Ren, Xi Liu, Yanning Cai, Zhe Wang   +8 more
wiley   +1 more source

Isolation and Ex Vivo Testing of CD8⁺ T-Cell Division and Activation Using Mouse Splenocytes. [PDF]

Bio Protoc
Dolan M, Shi Y, McKenery A, Tzetzo S, Chida K, Takabe K, Abrams SI, Ebos JML.   +7 more
europepmc   +1 more source