Results 141 to 150 of about 17,686 (257)

Systems biology approach unveils the cellular and molecular mechanisms of formalin-inactivated whole cell vaccine-induced protective immunity against <i>Coxiella burnetii</i> infection in mice. [PDF]

Front Immunol
Kumaresan V, Wang D, Zhang Y, Xu D, Zhang G.   +4 more
europepmc   +1 more source

IL‐33/ST2 Signaling Sustains Hepato‐Intestinal Homeostasis by Orchestrating Vascular Surveillance and Immune Regulatory Circuits During Experimental Trypanosoma cruzi Infection

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Impairment of hepato‐intestinal homeostasis triggered by ST2 deficiency during T. cruzi infection. Within the splenic compartment, immune dysregulation is marked by a robust pro‐inflammatory polarization of the T‐cell landscape. In the liver, ST2 deficiency is associated with hepatocellular injury, increased parasite burden, and hyperalbuminemia ...
Marcelo Eduardo Cardozo, Tatyane Martins Cirilo, José Bryan da Rocha Rihs, Jorge Lucas Nascimento Souza, Isabela de Brito Duval, Ana Rafaela Antunes‐Porto, Luisa Vitor Braga do Amaral, Fernando Bento Rodrigues Oliveira, Mayra Fernanda Ricci, Laura Lis de Oliveira Santos, Lívia Fernanda Dias Santana, Luiza Pinheiro Silva, Chiara Cássia Oliveira Amorim, Gabriela Gomes Monteiro Lemos, Getulío Mota e Silva Junior, Izabela da Silva Oliveira, Marina Possa dos Reys, Ana Laura Grossi de Oliveira, Geovanni Dantas Cassali, Luisa Mourão Dias Magalhães, Lilian Lacerda Bueno, Fabiana Simão Machado, Ricardo Toshio Fujiwara   +22 more
wiley   +1 more source

CD32b defines distinct dendritic cell lineages generated from the culture of bone marrow with GM-CSF. [PDF]

Front Immunol
Choi W, Ryu SH, Park JS, Park DE, Chu MK, Na HY, Park CG.   +6 more
europepmc   +1 more source

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang, Mengxuan Chen, Yan Ge, William Gunning, Rujun Gong   +4 more
wiley   +1 more source

Long-Term Administration of BTH2 Hypoallergenic Vaccine Candidate Induces Hallmarks of Allergen Immunotherapy in Murine Model of <i>Blomia tropicalis</i>-Induced Asthma. [PDF]

Biomedicines
da Silva ES, Fernandes AMS, Silva RC, de Souza LM, Sousa JEA, Orrico-Ferreira CM, Alcântara-Neves NM, Pacheco LGC, Pinheiro CDS.   +8 more
europepmc   +1 more source

Freeze-Dried, Not Frozen: Lyophilized Mesenchymal Stromal Cell-Derived Extracellular Vesicles and Therapeutic Function in Neuroinflammatory Models. [PDF]

J Am Coll Surg
Ashley JR, Collier AM, Olson SD, Cox CS.
europepmc   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

Advanced Science, Volume 13, Issue 38, 9 July 2026.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang, Yuchao Chen, Chuanjian Lu, Huazhen Liu, Fenglian Qin, Sisi Dai, Feifei Qiu, Haiming Chen, Weihui Lu, Jonathan S. Bromberg, Zhenhua Dai   +10 more
wiley   +1 more source

Evaluation of Immunotoxicity Induced by Organophosphorus Pesticide Malathion. [PDF]

Toxics
Zhang W, Lou M, Yong L, Xiao X, Liang C, Wang W, Yang H, Jia X, Wang Y, Song Y.   +9 more
europepmc   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, Volume 13, Issue 40, 17 July 2026.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Intravenous immunotherapy with Der p 1-containing nanoparticles alleviates the allergic responses in a murine allergic rhinitis model. [PDF]

Hum Vaccin Immunother
Park YM, Kim H, Kim JA, Lee HJ, Chun YH.
europepmc   +1 more source