Results 191 to 200 of about 20,678 (288)

Triiodothyronine-driven pro-inflammatory responses of dendritic cells are restrained by sphingolipid signaling. [PDF]

J Endocrinol
Negretti-Borga DM, Pires Teixeira M, Blanco A, Puentes EN, Soler MF, Alamino VA, Donadio AC, Clarke CJ, Montesinos MDM, Hannun YA, Pellizas CG.   +10 more
europepmc   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

METTL3-m⁶A-STAT1/NF-κB axis: a key switch for the immunosuppressive capacity of mesenchymal stem cells. [PDF]

Cell Mol Biol Lett
Tang K, Han H, Sun R, Xu Y, Zhang S, Lai C, Peng Y.   +6 more
europepmc   +1 more source

Endophytic Fungi Natural Factories of Novel Bioactive Compounds

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev, Jakhongir Movlanov, Liu Wei, Wei Liu, Maksud Isokov, Santosh Kumar Bose, Fazliddin Kobilov, Zamira Djumayeva, Buston Islamov, Jamila Sherkulova, Zafar Matyakubov, Muniskhon Meylieva, Munisa Ergasheva, Diyor Abduraxmanov, Guozheng Huang, Hongchen Jiang, Kakhramon Davranov, Guohui Pan, Nigora Rustamova   +18 more
wiley   +1 more source

Combination GLP-1RA and Low-Dose IL-2 Modulates Peripheral Immune Activation and Attenuates CNS Inflammatory Transcript Signatures In Vivo. [PDF]

Int J Mol Sci
Thome AD, Wang J, Faridar A, Zhao W, Saetzler V, Beers DR, Appel SH.   +6 more
europepmc   +1 more source

Herbal Extracts and Plant‐Derived Bioactives in Atopic Dermatitis: Evidence, Mechanisms, Pediatric Safety, and Translational Priorities

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Food‐derived bioactives, herbal extracts, and standardized botanical products are being investigated as adjunctive strategies for atopic dermatitis. Their biological activity is shaped not only by plant source and nominal dose, but also by fermentation, drying, heating, extraction, food‐matrix binding, gastrointestinal transformation, and formulation ...
Muhuang Zeng, Qianlan Yuan, Shuojia Huang, Xiaofei Lu   +3 more
wiley   +1 more source

Evaluation of humoral and cellular immune responses induced by a novel YidRv subunit vaccine from hypervirulent <i>Klebsiella pneumoniae</i>. [PDF]

BioTechnologia (Pozn)
Raras TYM, Ajrullah MJ, Rahma LN, Puspaningsih NNT, Nugraha RYB, Prawiro SR.   +5 more
europepmc   +1 more source

Dietary Microbial Polysaccharides in Food Systems: Production, Functional Properties, and Applications

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Microbial polysaccharides from fungi, bacteria, and microalgae exhibit diverse structures and biological activities. Their antioxidant, antimicrobial, immunomodulatory, and prebiotic properties highlight their potential as functional ingredients for food applications.
Hye‐Bin Lee, Yu‐Rim Chae, Yu Ra Lee, Yoonsook Kim, Ho‐Young Park   +4 more
wiley   +1 more source

Dual role of homocysteine in enhancing metabolic activity and suppressing inflammatory cytokines in murine immune cells. [PDF]

Korean J Physiol Pharmacol
Ho TL, Ko EJ.
europepmc   +1 more source

High‐dimensional spectral flow cytometry uncovers progressive T‐cell exhaustion and myeloid cell reprogramming in a CLL mouse model

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Chronic lymphocytic leukemia (CLL) exhibits marked clinical heterogeneity that cannot be fully explained by genetic alterations, underscoring the critical role of the tumor microenvironment in disease progression and therapeutic resistance.
Hannah Briesch, Mariana Coelho, Alessia Floerchinger, Yuliia Borysovych, Nicolas Aubert, Daniel Medina‐Gil, Manina Breitinger, Marc Zapatka, Stella E. Autenrieth, Martina Seiffert   +9 more
wiley   +1 more source