Fluvastatin promotes Th2‐skewed immune responses through direct effects on CD4+ T cells and, importantly, by altering dendritic cells (DCs) during differentiation. Continuous exposure at a near‐physiological concentration modifies DC phenotype and enhances their subsequent Th2‐polarizing capacity.
Satoshi Ishikawa +7 more
wiley +1 more source
Immune effects of lipids isolated from <i>Oncorhynchus mykiss</i> eggs on cyclophosphamide-induced immunosuppression in mice. [PDF]
Kim OJ +7 more
europepmc +1 more source
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo +7 more
wiley +1 more source
Deletion of <i>steD</i> gene and <i>yejAE</i> operons in LPS-deficient <i>Salmonella</i> elicits strong t cell immunity and complete protection against homologous serotypes. [PDF]
Zhou G +5 more
europepmc +1 more source
ABSTRACT Sepsis, a life‐threatening condition characterized by systemic inflammation and immune dysregulation, remains a major cause of mortality worldwide. Here, we identify a synthetic sulfonamide intermediate, 1‐[5‐(2‐fluorophenyl)furan‐2‐yl]‐N‐(4‐methylbenzyl)methanamine (FMM), as a host‐directed therapeutic candidate that enhances neutrophil ...
Ji Ye Park +10 more
wiley +1 more source
Tea saponin-soybean oil submicron emulsion promotes durable protective immunity against <i>Pasteurella multocida</i>. [PDF]
Cui X +9 more
europepmc +1 more source
Freeze-Dried, Not Frozen: Lyophilized Mesenchymal Stromal Cell-Derived Extracellular Vesicles and Therapeutic Function in Neuroinflammatory Models. [PDF]
Ashley JR, Collier AM, Olson SD, Cox CS.
europepmc +1 more source
Traditional Korean <i>Doenjang</i> Restores Splenic and NK Cell Function in Cyclophosphamide-Induced Immunosuppressed Rats. [PDF]
Lee HY +12 more
europepmc +1 more source
Stem Cell Therapy for Traumatic Brain Injury: Translational Mechanisms, Biomarkers, and Clinical Trials. [PDF]
Creel WT, Randhawa S, Hartman RE.
europepmc +1 more source
B cell CD19 is transferred between immune cells in mice and humans. [PDF]
Ochs J +9 more
europepmc +1 more source

