Results 51 to 60 of about 20,678 (288)
Atrazine-induced apoptosis of splenocytes in BALB/C mice [PDF]
BMC Medicine, 2011 Atrazine (2-chloro-4-ethytlamino-6-isopropylamine-1,3,5-triazine; ATR), is the most commonly applied broad-spectrum herbicide in the world. Unintentional overspray of ATR poses an immune function health hazard. The biomolecular mechanisms responsible for ATR-induced immunotoxicity, however, are little understood.
Zheng Jing +5 more
openaire +3 more sources
Effects of S. japonicum infection on splenocyte proliferation.
, 2013 S. japonicum infection inhibited splenocyte proliferation in vitro. 12 weeks after CII immunization in DBA/1 mice, splenocytes were cultured in RPMI 1640 containing 10% fetal calf serum for 72 hrs in the presence of polyclonal (ConA 5 µg/ml) or antigen ...
Xiaorong Song (104742) +8 more
core +1 more source
Advanced Science, EarlyView.Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki +7 more
wiley +1 more source
C19-Norditerpenoid Alkaloids from Aconitum szechenyianum
Molecules, 2018 Three new C19-norditerpenoid alkaloids (1–3), along with two known C19-norditerpenoid alkaloids (4,5), have been isolated from Aconitum szechenyianum.
Bei Song +8 more
doaj +1 more source
Experimental Biology and Medicine, 2001 Etiological agents of autoimmune processes that have been made nonvirulent by several treatments, i.e., mitomycin C (Mit C), can be used as a vaccine to protect against disease. In this work we studied the effects of splenocytes from diabetic mice on animals that had been injected with modified splenocytes (Mit C-treated splenocytes from multiple low ...
M, Arata +4 more
openaire +2 more sources
Distribution of injected splenocyte-derived myeloid cells in healed mouse skin.
, 2022 (A) Schematic figure of Dil-labeled or GFP-expressing mouse myeloid cell lineage tracing experiments. Splenocytes were isolated from spleens of Balb/C or C57BL/6-Tg (UBC-GFP) mice and cultured in a medium containing 5 ng/ml of M-CSF to generate myeloid ...
Yunyuan Li (321717) +3 more
core +1 more source
Advanced Science, EarlyView.Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Tolerance and cross-tolerance to splenocyte cytokine release is unaffected by blocking PD-1.
, 2015 The presented data was derived from at least 3 independent experiments, each in triplicate. Data represents splenocyte cytokine release 48 hours after successive 24-hour exposures to the ligand treatment combinations detailed on the X-axis.
Elliott D. Crouser (219388) +5 more
core +1 more source
Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery
Advanced Science, EarlyView.Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae +27 more
wiley +1 more source
Effect of CCR2 gene deletion on BPNM-induced splenocyte proliferation in vitro.
, 2014 Bar histographs depicting the mean absorbance of cultured splenocytes (optical density at 485 nm minus optical density at 595 nm; directly proportional to the number of viable cells) following treatment with bovine peripheral nerve myelin (BPNM) or ...
Nejla Yosef (535494) +6 more
core +1 more source