Results 31 to 40 of about 2,990,182 (255)
RNA splicing: a split consensus reveals two major 5′ splice site classes
Open BiologyThe established consensus sequence for human 5′ splice sites masks the presence of two major splice site classes defined by preferential base-pairing potentials with either U5 snRNA loop 1 or the U6 snRNA ACAGA box.
Matthew T. Parker +2 more
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ST5 - Revised Splice of ODP Site 162-982
, 2017 ST5 - Revised Splice of ODP Site 162 ...
Drury, Anna Joy +7 more
core +1 more source
In silico prioritization and further functional characterization of SPINK1 intronic variants
Human Genomics, 2017 Background SPINK1 (serine protease inhibitor, kazal-type, 1), which encodes human pancreatic secretory trypsin inhibitor, is one of the most extensively studied genes underlying chronic pancreatitis.
Wen-Bin Zou +7 more
doaj +1 more source
New methods for splice site recognition
, 2022 S.329-336Splice sites are locations in DNA which separate protein-coding regions (exons) from noncoding regions (introns). Accurate splice site detectors thus form important components of computational gene finders.
Sonnenburg, S. +3 more
core +1 more source
International Journal of Genomics, 2022 Assessing the impact of variants of unknown significance on splicing has become a critical issue and a bottleneck, especially with the widespread implementation of whole-genome or exome sequencing.
Woori Jang +3 more
doaj +1 more source
Computational methods for splice site prediction [PDF]
, 2006 Taher L. Computational methods for splice site prediction. Bielefeld (Germany): Bielefeld University; 2006.Completing the genome sequence of a given organism is just the beginning of a series of subsequent tasks, namely, the discovery of the ...
Taher, Leila
core
Examples of splice site polymorphisms.
, 2018 The solid lines with numbers indicate splice junctions with a polymorphism in the donor or acceptor site, while the dashed lines with numbers indicate other “normal” splice junctions that share either the donor or acceptor sites with the polymorphic ...
Jinze Liu (383649) +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
BMC Plant Biology, 2023 Background Nitrogen-fixing nodules occur in ten related taxonomic lineages interspersed with lineages of non-nodulating plant species. Nodules result from an endosymbiosis between plants and diazotrophic bacteria; rhizobia in the case of legumes and ...
Sultan Alhusayni +9 more
doaj +1 more source
Splice site prediction software output.
, 2014 The scores of the preprocessing models reflect the splice site strength. Abbreviations: HSF (Human Splice Finder), SP (Splice Port) and ASSP (Alternative Splice Site Predictor).
Gloria B. Aranda (591587) +7 more
core +1 more source