Results 211 to 220 of about 34,718 (253)

An SpC editor targeting pre-mRNA splicing for precise CRISPR control and enhanced antitumor efficacy. [PDF]

Nucleic Acids Res
Shi X, Hu C, Jia L, Lei Z, Guo B, Zhou J, Wang F.   +6 more
europepmc   +1 more source

Genome-wide CRISPR screen reveals an uncharacterized spliceosome regulator as new candidate immunotherapy target. [PDF]

Imeta
Shao T, Liu C, Kuang J, Xie S, Qu Y, Li Y, Zhang L, Liu F, Qi Y, Hou T, Li M, Zhang S, Liu Y, Yuan Z, Liu J, Hu Y, Wang J, Song C, Zhang S, Zhu L, Shao J, Lin A, Mao W, Wang G, Zhu L.   +24 more
europepmc   +1 more source

CDK7-CDK11 axis in spliceosome regulation and pre-mRNA splicing. [PDF]

Nucleic Acids Res
Rájecký M, Gajdušková P, Maník P, Hluchý M, Hegedűsová E, Kryštofová K, Potěšil D, Martinková P, Slabá Z, Khirsariya P, Šebesta M, Paruch K, Friedel CC, Zdráhal Z, Blazek D.   +14 more
europepmc   +1 more source

Alternative Splicing Dysregulation in Retinitis Pigmentosa: Pathogenic Mechanisms and Therapeutic Opportunities. [PDF]

Biomolecules
Jiang Y, Liu X, Fu J, Wu Y, Yu S, Yao K.
europepmc   +1 more source

A Plot Twist: When RNA Yields Unexpected Findings in Paired DNA-RNA Germline Genetic Testing. [PDF]

Genes (Basel)
Zimmermann H, Brannan T, Young C, Ramirez Castano J, Horton C, Richardson A, Molparia B, Richardson ME.   +7 more
europepmc   +1 more source

Knockdown of the fly spliceosome component Rbp1 (orthologue of SRSF1 ) extends lifespan

Hayman DJ, Simons MJP.
europepmc   +1 more source

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Architecture of the Spliceosome

Biochemistry, 2012
Precursor-mRNA splicing is catalyzed by an extraordinarily large and highly dynamic macromolecular assemblage termed the spliceosome. Detailed biochemical and structural study of the spliceosome presents a formidable challenge, but there has recently been significant progress made on this front highlighted by the crystal structure of a 10-subunit human
Clarisse, van der Feltz, Kelsey, Anthony, Axel, Brilot, Daniel A, Pomeranz Krummel   +3 more
openaire   +2 more sources