Results 291 to 300 of about 58,017 (329)

The green side of splicing: algal spliceosome shows remarkable structural conservation. [PDF]

EMBO J
Galej WP.
europepmc   +1 more source

A <i>Mycobacterium tuberculosis</i> secreted virulence factor Rv1435c/hsr1 disrupts host snRNP biogenesis. [PDF]

Proc Natl Acad Sci U S A
Chauhan K, Datta D, Kapoor Y, Passricha N, Dutt R, Arora N, Das M, Rao K, Singh L, Gautam A, Sharma RD, Sarkar B, Yadav M, Malakar B, Kalam H, Saini P, Mehra L, Das P, Ahuja V, Ahuja V, Singhal A, Nandicoori V, Kumar D.   +22 more
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Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder

Greene D, Mendez R, Lees J, Barbosa M, Bruselles A, Chiriatti L, Mancini C, Undiagnosed Diseases Network, Bertini ES, Bonner DE, Cassini TA, Ezell KM, Gomez-Ospina N, Rives L, Shashi V, Spillmann RC, Wafik M, Tartaglia M, Bernstein JA, Mumford AD, Wheeler MT, Turro E.   +21 more
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Identification of RNA binding proteins that mediate a quality control mechanism of splicing

Arafat M, Gotea V, Umar MI, Muharram A, Kamhi E, Agami R, Sperling J, Hafner M, Elnitski L, Sperling R.   +9 more
europepmc   +1 more source

Pervasive splicing in a plant DNA virus

Pott DM, Gao M, Shi C, Wang L, Medina-Puche L, Yagci Z, Acatay SA, Zhang J, Gonzalo L, Merchante C, Gu L, Lozano-Durán R.   +11 more
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RNA Splicing by the Spliceosome.

Annual Review of Biochemistry, 2019
The spliceosome removes introns from messenger RNA precursors (pre-mRNA). Decades of biochemistry and genetics combined with recent structural studies of the spliceosome have produced a detailed view of the mechanism of splicing.
M. E. Wilkinson, C. Charenton, K. Nagai
semanticscholar   +1 more source

Roles of minor spliceosome in intron recognition and the convergence with the better understood major spliceosome

Wiley Interdisciplinary Reviews - RNA, 2022
Catalyzed by spliceosomes in the nucleus, RNA splicing removes intronic sequences from precursor RNAs in eukaryotes to generate mature RNA, which also significantly increases proteome complexity and fine‐tunes gene expression.
Zhan Ding, Yan-Ran Meng, Yu-Jie Fan, Yong-Zhen Xu   +3 more
semanticscholar   +1 more source

Transcriptome-wide splicing network reveals specialized regulatory functions of the core spliceosome.

Science
The spliceosome is the complex molecular machinery that sequentially assembles on eukaryotic messenger RNA precursors to remove introns (pre-mRNA splicing), a physiologically regulated process altered in numerous pathologies. We report transcriptome-wide
M. Rogalska, Estefanía Mancini, Sophie Bonnal, André Gohr, Bryan M Dunyak, N. Arecco, Peter G Smith, Frédéric H. Vaillancourt, Juan Valcárcel   +8 more
semanticscholar   +1 more source